intracellular acid
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Polyprodrug with ultra-high drug content for tumor intracellular acid-triggered degradation and drug delivery

2021 ◽  
pp. 110820
Author(s):  
Xinming Li ◽  
Xiaomei Zhao ◽  
Peng Liu
Keyword(s):  
Drug Delivery ◽  
High Drug ◽  
Drug Content ◽  
Intracellular Acid

Comparative physiology investigations support a role for histidine-containing dipeptides in intracellular acid–base regulation of skeletal muscle

2019 ◽  
Vol 234 ◽  
pp. 77-86 ◽  
Author(s):  
Eimear Dolan ◽  
Bryan Saunders ◽  
Roger Charles Harris ◽  
Jose Eduardo Pereira Wilken Bicudo ◽  
David John Bishop ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Comparative Physiology ◽  
Acid Base ◽  
Intracellular Acid

Design, postpolymerization conjugation and self-assembly of a di-block copolymer-based prodrug for tumor intracellular acid-triggered DOX release

2019 ◽  
Vol 7 (37) ◽  
pp. 5640-5647 ◽  
Author(s):  
Yuman Dong ◽  
Pengcheng Du ◽  
Mingliang Pei ◽  
Peng Liu
Keyword(s):  
Polyethylene Glycol ◽  
Block Copolymer ◽  
Atom Transfer Radical Polymerization ◽  
Radical Polymerization ◽  
Self Assembly ◽  
Glycidyl Methacrylate ◽  
Atom Transfer ◽  
Imine Bond ◽  
Acid Labile ◽  
Intracellular Acid

A novel di-block copolymer-based prodrug was designed by atom transfer radical polymerization (ATRP) of glycidyl methacrylate (GMA) with a polyethylene glycol-based initiator (PEG-Br), postpolymerization aldehyde-modification, and doxorubicin (DOX) conjugation via an acid-labile imine bond.

scholarly journals Tumor-targeted biopolymer capped mesoporous silica nanocarriers for intracellular acid-triggered drug release

2016 ◽  
Vol 4 ◽  
Author(s):  
Mart�nez-Carmona Marina ◽  
Colilla Montserrat ◽  
Lozano Daniel ◽  
Vallet-Reg� Mar�a
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Triggered Drug Release ◽  
Intracellular Acid

Construction and evaluation of PAMAM–DOX conjugates with superior tumor recognition and intracellular acid-triggered drug release properties

2015 ◽  
Vol 136 ◽  
pp. 37-45 ◽  
Author(s):  
Lifang Cheng ◽  
Qing Hu ◽  
Liang Cheng ◽  
Wen Hu ◽  
Ming Xu ◽  
...  
Keyword(s):  
Drug Release ◽  
Tumor Recognition ◽  
Triggered Drug Release ◽  
Intracellular Acid

Loading of Cells with Fluorescent Probe to Study Intracellular Acid-base Homeostasis in Lactic Acid Bacteria

BIO-PROTOCOL ◽  
2015 ◽  
Vol 5 (2) ◽  
Author(s):  
Pablo Mortera ◽  
Federico Zuljan ◽  
Christian Magni ◽  
Sergio Alarc�n
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Fluorescent Probe ◽  
Acid Base ◽  
Intracellular Acid

scholarly journals Innentitelbild: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. 2/2015)

2014 ◽  
Vol 127 (2) ◽  
pp. 374-374
Author(s):  
Daniela Pizzirani ◽  
Anders Bach ◽  
Natalia Realini ◽  
Andrea Armirotti ◽  
Luisa Mengatto ◽  
...  
Keyword(s):  
Acid Ceramidase ◽  
Intracellular Acid

scholarly journals Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Daniela Pizzirani ◽  
Anders Bach ◽  
Natalia Realini ◽  
Andrea Armirotti ◽  
Luisa Mengatto ◽  
...  
Keyword(s):  
Acid Ceramidase ◽  
Intracellular Acid
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