A Long-Term, Multicenter, Double-Blind Study of an Escherichia Coli Extract (OM-89) in Female Patients with Recurrent Urinary Tract Infections

2005 ◽  
Vol 47 (4) ◽  
pp. 542-548 ◽  
Author(s):  
Hartwig W. Bauer ◽  
Schanaz Alloussi ◽  
Günther Egger ◽  
Hans-Martin Blümlein ◽  
Gabriel Cozma ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Female Patients ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections

Chronic Urinary Tract Infections in Children: A Double-Blind Study of Medical Management

PEDIATRICS ◽  
1970 ◽  
Vol 45 (3) ◽  
pp. 456-461
Author(s):  
C. George RAY ◽  
Yi-Chuan Ching ◽  
David B. Shurtleff ◽  
Margaret L. Hill ◽  
Julian S. Ansell ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Medical Management ◽  
Asymptomatic Bacteriuria ◽  
Double Blind Study ◽  
Careful Evaluation ◽  
Double Blind ◽  
Continuous Therapy ◽  
Tract Infections

Nine children with nonobstructive urinary tract infections, 10 children with neurogenic bladders secondary to meningomyeloceles, and 2 children with ileal bladders have been studied in a double-blind program of medical management for recurrent urinary tract infections. Observations indicate that some patients with nonobstructive recurrent UTI's may benefit from long-term chemoprophylaxis; however, the effective drug may vary from patient to patient. Furthermore, not all patients need continuous therapy, although initial clinical differentiation is not currently possible. In all patients, the essence of management consists of frequent, careful evaluation, with periodic assessment of anatomic and functional status of the urinary tract. Among children with anatomic and physiologic abnormalities of the urinary tract, neither continuous chemotherapy nor therapy of asymptomatic bacteriuria appears beneficial.

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