809 Long-term, multicenter, double-blind study of prophylactic treatment of recurrent urinary tract infections in female patients using an escherichia coli extract (OM-89)

2004 ◽  
Vol 3 (2) ◽  
pp. 205
Author(s):  
C. Schulman ◽  
M. Vanden Bossche ◽  
S. Alloussi ◽  
G. Cozma
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Prophylactic Treatment ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections

Chronic Urinary Tract Infections in Children: A Double-Blind Study of Medical Management

PEDIATRICS ◽  
1970 ◽  
Vol 45 (3) ◽  
pp. 456-461
Author(s):  
C. George RAY ◽  
Yi-Chuan Ching ◽  
David B. Shurtleff ◽  
Margaret L. Hill ◽  
Julian S. Ansell ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Medical Management ◽  
Asymptomatic Bacteriuria ◽  
Double Blind Study ◽  
Careful Evaluation ◽  
Double Blind ◽  
Continuous Therapy ◽  
Tract Infections

Nine children with nonobstructive urinary tract infections, 10 children with neurogenic bladders secondary to meningomyeloceles, and 2 children with ileal bladders have been studied in a double-blind program of medical management for recurrent urinary tract infections. Observations indicate that some patients with nonobstructive recurrent UTI's may benefit from long-term chemoprophylaxis; however, the effective drug may vary from patient to patient. Furthermore, not all patients need continuous therapy, although initial clinical differentiation is not currently possible. In all patients, the essence of management consists of frequent, careful evaluation, with periodic assessment of anatomic and functional status of the urinary tract. Among children with anatomic and physiologic abnormalities of the urinary tract, neither continuous chemotherapy nor therapy of asymptomatic bacteriuria appears beneficial.

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