scholarly journals Molecular characterization of the human lens epithelium-derived cell line SRA01/04

2019 ◽  
Vol 188 ◽  
pp. 107787 ◽  
Author(s):  
Bailey A.T. Weatherbee ◽  
Joshua R. Barton ◽  
Archana D. Siddam ◽  
Deepti Anand ◽  
Salil A. Lachke
1999 ◽  
Vol 277 (3) ◽  
pp. C412-C424 ◽  
Author(s):  
Allan R. Shepard ◽  
James L. Rae

We describe the cloning and characterization of the first human members, hKv9.1 and hKv9.3, of the electrically silent delayed-rectifying-like K+channel subfamily. Their modulatory effects on the electrically active subfamily member hKv2.1 are also quantified. The hKv9 K+channels were isolated from a human lens epithelium cDNA library, but both hKv9.1 mRNA and hKv9.3 mRNA were found to coexist with the mRNA for hKv2.1 in a large number of human tissues. The hKv9.1 gene is composed of a minimum of five exons, with at least two alternatively spliced exons in the 5′-untranslated region (UTR). In contrast, the hKv9.3 gene is intronless across the coding region, 3′-UTR, and all of the analyzed 5′-UTR. Radiation hybrid mapping localized the hKv9.1 gene to 20q12 and the hKv9.3 gene to 2p24. Each electrically silent subunit, when coexpressed with hKv2.l, slows deactivation and inactivation compared with hKv2.1 expressed alone. In addition, each results in an increment in the single channel conductance.


2003 ◽  
Vol 95 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Mauro Mandrioli ◽  
Silvia Bugli ◽  
Sabrina Saltini ◽  
Susanna Genedani ◽  
Enzo Ottaviani

2016 ◽  
Vol 57 (10) ◽  
pp. 4063 ◽  
Author(s):  
Rosana Mesa ◽  
Manoj Tyagi ◽  
George Harocopos ◽  
David Vollman ◽  
Steven Bassnett

1990 ◽  
Vol 2 (1) ◽  
pp. 71-73 ◽  
Author(s):  
Margaret J. Jeffrey ◽  
W.T. Green ◽  
D.L. Boase ◽  
M.N. Jeffrey

RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16596-16605 ◽  
Author(s):  
Belal I. Hanafy ◽  
Gareth W. V. Cave ◽  
Yvonne Barnett ◽  
Barbara Pierscionek

Nanoceria (<5 nm), stabilised with ethylene glycol, protects human lens epithelium from oxidative stress and exhibits multicoloured photoluminescence.


1991 ◽  
Vol 86 (6) ◽  
Author(s):  
G�nter Rudolph ◽  
Karin Schilbach-St�ckle ◽  
Rupert Handgretinger ◽  
Peter Kaiser ◽  
Horst Hameister

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