scholarly journals Corrigendum to “In silico and in vitro analysis of cation-activated potassium channels in human corneal endothelial cells” [Experimental Eye Research (Aug; 2020) 197:108114]

2021 ◽  
Vol 211 ◽  
pp. 108757
Author(s):  
Diana Amador-Muñoz ◽  
Angela María Gutiérrez ◽  
César Payán Gómez ◽  
Luisa Marina Matheus
Keyword(s):  
Endothelial Cells ◽  
Potassium Channels ◽  
In Silico ◽  
Corneal Endothelial Cells ◽  
Human Corneal Endothelial Cells ◽  
Vitro Analysis ◽  
In Vitro Analysis

In silico and in vitro analysis of cation-activated potassium channels in human corneal endothelial cells

2020 ◽  
Vol 197 ◽  
pp. 108114
Author(s):  
Diana Amador-Muñoz ◽  
Ángela María Gutiérrez ◽  
César Payán-Gómez ◽  
Luisa Marina Matheus
Keyword(s):  
Endothelial Cells ◽  
Potassium Channels ◽  
In Silico ◽  
Corneal Endothelial Cells ◽  
Human Corneal Endothelial Cells ◽  
Vitro Analysis ◽  
In Vitro Analysis

scholarly journals Human Corneal Endothelial Cells Expanded In Vitro Are a Powerful Resource for Tissue Engineering

2017 ◽  
Vol 14 (2) ◽  
pp. 128-135 ◽  
Author(s):  
Yongsong Liu ◽  
Hong Sun ◽  
Min Hu ◽  
Min Zhu ◽  
Sean Tighe ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Endothelial Cells ◽  
Corneal Endothelial Cells ◽  
Human Corneal Endothelial Cells

In silico Repurposing of Anticancer Drug (5-Fluorouracil) as an Antibacterial Agent against Klebsiella pneumoniae

2021 ◽  
Vol 18 ◽  
Author(s):  
Amey Sharma ◽  
Apoorva Rana ◽  
Lakshya Mangtani ◽  
Aakanksha Kalra ◽  
Ravi Ranjan Kumar Niraj
Keyword(s):  
Molecular Docking ◽  
Klebsiella Pneumoniae ◽  
Thymidylate Synthase ◽  
In Silico ◽  
Homology Modelling ◽  
Klebsiella Pneumonia ◽  
Drug Resistant ◽  
Vitro Analysis ◽  
In Vitro Analysis

Background: Infections caused by drug resistant microorganisms have been increasing worldwide thereby being one of the major causes of morbidity in the 21st century. Klebsiella pneumoniae is one such bacteria causing lung inflammation, lung injury and death. Emergence of hyper-virulent and drug resistant species such as ESBL and CRKP has made this microbe a serious and urgent threat. The pace of emergence of these species is outgrowing the development of novel drug and vaccine candidates thereby focusing on drug repurposing approach. Objective: 1. Homology Modelling of Thymidylate Synthase. 2. Verification of Modelled Structure. 3. Molecular Docking. 4. Molecular Dynamic Simulation of Docked Complex. 5. In vitro analysis of 5-FU activity against Klebsiella pneumonia. Method: The 3-D structure of Thymidylate Synthase was predicted using Swiss-Model server and validated by in silico approaches. - Determination protein-protein interactions using STRING database. - Molecular docking. - MD simulations of 5-FU with predicted structure of thymidylate synthase. - In vitro antimicrobial drug sensitivity assay at different concentrations. Result: Hydrogen bond was observed in Molecular Docking - Protein-ligand complex remains stable during simulation. - 5-FU shows antimicrobial activity against Klebsiella pneumonia during In vitro study. Conclusion: Both In silico as well as in vitro analysis have indicated that 5-FU can potentially be developed as an antimicrobial agent towards Klebsiella pneumonia

scholarly journals Novel Promoters Derived from Chinese Hamster Ovary Cells via In Silico and In Vitro Analysis

2019 ◽  
Vol 14 (11) ◽  
pp. 1900125 ◽  
Author(s):  
Ly N. Nguyen ◽  
Martina Baumann ◽  
Heena Dhiman ◽  
Nicolas Marx ◽  
Valerie Schmieder ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
In Silico ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Vitro Analysis ◽  
In Vitro Analysis

In vitro analysis of the trajectories of adhesive microbubbles approaching endothelial cells

2020 ◽  
Vol 578 ◽  
pp. 758-767
Author(s):  
Barbara Cerroni ◽  
Flavia Righi Riva ◽  
Letizia Oddo ◽  
Fabio Domenici ◽  
Elisabetta Tortorella ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Vitro Analysis ◽  
In Vitro Analysis

Role of Human Corneal Endothelial Cells in T-Cell–Mediated Alloimmune Attack In Vitro

2014 ◽  
Vol 55 (3) ◽  
pp. 1213 ◽  
Author(s):  
Imad Lahdou ◽  
Christoph Engler ◽  
Stefan Mehrle ◽  
Volker Daniel ◽  
Mahmoud Sadeghi ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
T Cell ◽  
Corneal Endothelial Cells ◽  
Human Corneal Endothelial Cells
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