Chronic cocaine administration modulates the expression of transcription factors involved in midbrain dopaminergic neuron function

2007 ◽  
Vol 203 (2) ◽  
pp. 472-480 ◽  
Author(s):  
D. Leo ◽  
U. di Porzio ◽  
G. Racagni ◽  
M.A. Riva ◽  
F. Fumagalli ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Dopaminergic Neuron ◽  
Cocaine Administration ◽  
Midbrain Dopaminergic Neuron ◽  
Chronic Cocaine ◽  
Neuron Function

scholarly journals Postnatal signalling with homeoprotein transcription factors

2014 ◽  
Vol 369 (1652) ◽  
pp. 20130518 ◽  
Author(s):  
Alain Prochiantz ◽  
Julia Fuchs ◽  
Ariel A. Di Nardo
Keyword(s):  
Transcription Factors ◽  
Visual Cortex ◽  
Choroid Plexus ◽  
Dopaminergic Neuron ◽  
Therapeutic Strategies ◽  
Embryonic Cell ◽  
Genetic Pathways ◽  
Physiological Functions ◽  
Autonomous Regulation ◽  
Midbrain Dopaminergic Neuron

Homeoprotein (HP) transcription factors were originally identified for their embryonic cell-autonomous developmental functions. In this review, we discuss their postnatal and adult physiological functions based on the study of Otx2, Engrailed-1 and Engrailed-2 (collectively Engrailed). For Engrailed, we discuss its function in the cell-autonomous regulation of ventral midbrain dopaminergic neuron survival and physiology and in the non-cell-autonomous maintenance of axons. For Otx2, we describe how the protein is expressed in the choroid plexus and transported into cortical parvalbumin cells where it regulates plasticity in the visual cortex. These two examples illustrate how the understanding of HP postnatal and adult functions, including signalling functions, may lead to the identification of disease-associated genetic pathways and to the development of original therapeutic strategies.

Cardiovascular Effects of Acute and Chronic Cocaine Administration in Pregnant and Nonpregnant Rabbits

1999 ◽  
Vol 158 (3) ◽  
pp. 278-287 ◽  
Author(s):  
Roy L. Sutliff ◽  
Pamela A. Gayheart-Walsten ◽  
David L. Snyder ◽  
Jay Roberts ◽  
Mark D. Johnson
Keyword(s):  
Cardiovascular Effects ◽  
Cocaine Administration ◽  
Chronic Cocaine

scholarly journals Regulation of firing frequency in a computational model of a midbrain dopaminergic neuron

2010 ◽  
Vol 28 (3) ◽  
pp. 389-403 ◽  
Author(s):  
Anna Y. Kuznetsova ◽  
Marco A. Huertas ◽  
Alexey S. Kuznetsov ◽  
Carlos A. Paladini ◽  
Carmen C. Canavier
Keyword(s):  
Computational Model ◽  
Dopaminergic Neuron ◽  
Firing Frequency ◽  
Midbrain Dopaminergic Neuron

Anxiogenic effects of acute and chronic cocaine administration: Neurochemical and behavioral studies

1992 ◽  
Vol 41 (3) ◽  
pp. 643-650 ◽  
Author(s):  
Xiao-Min Yang ◽  
A.Laurel Gorman ◽  
Adrian J. Dunn ◽  
Nick E. Goeders
Keyword(s):  
Cocaine Administration ◽  
Behavioral Studies ◽  
Chronic Cocaine

Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP

2017 ◽  
Vol 10 (493) ◽  
pp. eaal4165 ◽  
Author(s):  
Dawei Zhang ◽  
Shanzheng Yang ◽  
Enrique M. Toledo ◽  
Daniel Gyllborg ◽  
Carmen Saltó ◽  
...  
Keyword(s):  
Dopaminergic Neuron ◽  
Neuron Survival ◽  
Midbrain Dopaminergic Neuron
Sign in / Sign up

Export Citation Format

Share Document