Research progress on Cordyceps militaris polysaccharides

2021 ◽  
pp. 101503
Author(s):  
Chunmei Gu ◽  
Debin Zhang ◽  
Wenjiao Zhai ◽  
Huipeng Zhang ◽  
Sida Wang ◽  
...  
Keyword(s):  
Cordyceps Militaris ◽  
Research Progress

scholarly journals New Insights Into the Biosynthesis of Typical Bioactive Components in the Traditional Chinese Medicinal Fungus Cordyceps militaris

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiuyun Wu ◽  
Tao Wu ◽  
Ailin Huang ◽  
Yuanyuan Shen ◽  
Xuanyu Zhang ◽  
...  
Keyword(s):  
Low Cost ◽  
Gene Clusters ◽  
Cordyceps Militaris ◽  
Research Progress ◽  
Microbial Cell Factories ◽  
Medicinal Fungus ◽  
Cell Factories ◽  
Wide Range ◽  
History Of ◽  
Bioactive Ingredients

Cordyceps militaris, a traditional medicinal ingredient with a long history of application in China, is regarded as a high-value fungus due to its production of various bioactive ingredients with a wide range of pharmacological effects in clinical treatment. Several typical bioactive ingredients, such as cordycepin, D-mannitol, cordyceps polysaccharides, and N6-(2-hydroxyethyl)-adenosine (HEA), have received increasing attention due to their antitumor, antioxidant, antidiabetic, radioprotective, antiviral and immunomodulatory activities. Here, we systematically sorted out the latest research progress on the chemical characteristics, biosynthetic gene clusters and pathways of these four typical bioactive ingredients. This summary will lay a foundation for obtaining low-cost and high-quality bioactive ingredients in large amounts using microbial cell factories in the future.

Which Data to Meta-Analyze, and How?

2019 ◽  
Vol 227 (1) ◽  
pp. 64-82 ◽  
Author(s):  
Martin Voracek ◽  
Michael Kossmeier ◽  
Ulrich S. Tran
Keyword(s):  
Empirical Research ◽  
Meta Analysis ◽  
Curve Analysis ◽  
Research Progress ◽  
Primary Data ◽  
Statistical Procedures ◽  
Graphical Displays ◽  
Primary Data Analysis ◽  
Meta Analyses ◽  
Data Analytic

Abstract. Which data to analyze, and how, are fundamental questions of all empirical research. As there are always numerous flexibilities in data-analytic decisions (a “garden of forking paths”), this poses perennial problems to all empirical research. Specification-curve analysis and multiverse analysis have recently been proposed as solutions to these issues. Building on the structural analogies between primary data analysis and meta-analysis, we transform and adapt these approaches to the meta-analytic level, in tandem with combinatorial meta-analysis. We explain the rationale of this idea, suggest descriptive and inferential statistical procedures, as well as graphical displays, provide code for meta-analytic practitioners to generate and use these, and present a fully worked real example from digit ratio (2D:4D) research, totaling 1,592 meta-analytic specifications. Specification-curve and multiverse meta-analysis holds promise to resolve conflicting meta-analyses, contested evidence, controversial empirical literatures, and polarized research, and to mitigate the associated detrimental effects of these phenomena on research progress.

Psychoanalytic Research: Progress and Process

2002 ◽  
Author(s):  
Raymond A. Levy ◽  
Stuart Ablon
Keyword(s):  
Research Progress
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