scholarly journals Energy dissipation of flow over the type-B Piano Key Weir

Author(s):  
Deepak Singh ◽  
Munendra Kumar
Water ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1253
Author(s):  
Kam R. Eslinger ◽  
Brian M. Crookston

A Piano Key weir (PK weir) is a nonlinear, labyrinth-type weir well suited for rehabilitation projects due to a relatively small footprint and the ability to pass large discharges for lesser upstream-head values when compared with other weir types. A critical component of a hydraulic structure is the energy-dissipative properties. Currently, information and guidance is limited, with previous energy dissipation studies of PK weirs primarily of specific projects. Therefore, to document and quantify energy dissipation, four laboratory-scale Type A PK weir models with different width ratios (Wi/Wo) were studied, with 255 tests comprising this new dataset, along with detailed observations of the flow field. Results were compared to existing published data regarding energy dissipation downstream of trapezoidal and rectangular labyrinth weirs. To support design efforts, two equations, both functions of head-water ratio (H/P) and Wi/Wo, are proposed to predict the relative residual energy downstream of PK weirs. The energy dissipation of PK weirs is largest at low flows and decreases in a logarithmic-like manner as flow increases. PK weirs with increased hydraulic efficiency, caused by an increase in Wi/Wo, resulted in slightly smaller energy dissipation values within the range 0.2 ≤ H/P ≤ 0.8. The energy dissipation of PK weirs was found to be relatively constant, independent of Wi/Wo, and in the ranges 0.07 ≤ H/P ≤ 0.2 and 0.8 ≤ H/P ≤ 0.95.


2013 ◽  
pp. 111-120 ◽  
Author(s):  
A Silvestri ◽  
P Archambeau ◽  
M Pirotton ◽  
B Dewals ◽  
S Erpicum

Author(s):  
S. Fujinaga ◽  
K. Maruyama ◽  
C.W. Williams ◽  
K. Sekhri ◽  
L. Dmochowski

Yumoto and Dmochowski (Cancer Res.27, 2098 (1967)) reported the presence of mature and immature type C leukemia virus particles in leukemic organs and tissues such as lymph nodes, spleen, thymus, liver, and kidneys of SJL/J strain mice with Hodgki's-like disease or reticulum cell neoplasm (type B). In an attempt to ascertain the possibility that this neoplasia may be of viral origin, experiments with induction and transmission of this neoplasm were carried out using cell-free extracts of leukemic organs from an SJL/J strain mouse with spontaneous disease.It has been possible to induce the disease in low-leukemia BALB/c and C3HZB strain mice and serially transfer the neoplasia by cell-free extracts of leukemic organs of these mice. Histological examination revealed the neoplasia to be of either reticulum cell-type A or type B. Serial transfer is now in its fifth passage. In addition leukemic spleen from another SJL/J strain mouse with spontaneous reticulum cell neoplasm (type A) was set up in tissue culture and is now in its 141st serial passage in vitro. Preliminary results indicate that cell-free material of 39th tissue culture passage can reproduce neoplasia in BALB/c mice.


Author(s):  
P. F. Flicker ◽  
V.S. Kulkarni ◽  
J. P. Robinson ◽  
G. Stubbs ◽  
B. R. DasGupta

Botulinum toxin is a potent neurotoxin produced by Clostridium botulinum. The toxin inhibits release of neurotransmitter, causing muscle paralysis. There are several serotypes, A to G, all of molecular weight about 150,000. The protein exists as a single chain or or as two chains, with two disulfide linkages. In a recent investigation on intracellular action of neurotoxins it was reported that type B neurotoxin can inhibit the release of Ca++-activated [3H] norepinephrine only if the disulfide bonds are reduced. In order to investigate possible structural changes in the toxin upon reduction of the disulfide bonds, we have prepared two-dimensional crystals of reduced type B neurotoxin. These two-dimensional crystals will be compared with those of the native (unreduced) type B toxin.


2004 ◽  
Vol 10 ◽  
pp. 37-38
Author(s):  
Lisa C. Moore ◽  
Archana Sadhu ◽  
Dorothy Martinez ◽  
Robin Kate Kelley
Keyword(s):  

2017 ◽  
Vol 23 ◽  
pp. 38-39
Author(s):  
Sheetal Malhotra ◽  
Shanaz Sikder ◽  
Elaine Cochran ◽  
Mattingly Megan ◽  
Gorden Phillip ◽  
...  

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