scholarly journals The impact of burial period on compact bone microstructure: Histological analysis of matrix loss and cell integrity in human bones exhumed from tropical soil

2019 ◽  
Vol 298 ◽  
pp. 384-392 ◽  
Author(s):  
Rafael Dias Astolphi ◽  
Maria Teresa de Seixas Alves ◽  
Martin Paul Evison ◽  
Raffaela Arrabaça Francisco ◽  
Marco Aurelio Guimarães ◽  
...  
Biologia ◽  
2019 ◽  
Vol 75 (7) ◽  
pp. 935-941
Author(s):  
Ramona Babosova ◽  
Vladimira Mondockova ◽  
Radoslav Omelka ◽  
Maria Bauerova ◽  
Drahomir Galbavy ◽  
...  

2009 ◽  
Vol 91 (3) ◽  
pp. 195-200 ◽  
Author(s):  
K Sillah ◽  
EA Griffiths ◽  
SA Pritchard ◽  
R Swindell ◽  
CM West ◽  
...  

INTRODUCTION Published colorectal cancer surgery data suggest no role for the analysis of the anastomotic doughnuts following anterior resection. The usefulness of routine histological analysis of the upper gastrointestinal doughnut is not clear. Our study assessed the impact of cancer involvement of the doughnut on clinical practice. Factors associated with doughnut involvement and the effect on patients' survival were also analysed. PATIENTS AND METHODS The clinicopathological details of 462 patients who underwent potentially curative oesophagogastrectomy for cancer with a stapled anastomosis between 1994 and 2006 in two specialist centres were retrospectively analysed. Univariate, multivariate and survival analyses were carried out. RESULTS Approximately 5% of doughnuts (22 of 462) were histologically involved with cancer. Microscopic involvement of the proximal resection margin, local lymph node metastasis and lymphatic invasion within the main resected specimen were independently associated with doughnut involvement (all P < 0.05). However, these three factors taken together failed to predict doughnut involvement. Doughnut involvement was an independent adverse prognostic factor for overall survival (P = 0.0013). CONCLUSIONS In contrast to findings in colorectal surgery, doughnut involvement with cancer appears to have useful prognostic information following oesophagogastrectomy. Routine histological analysis of upper gastrointestinal doughnuts is justified. Doughnut involvement could potentially strengthen the indications for adjuvant therapy in the future.


2019 ◽  
Vol 109 ◽  
pp. 104989 ◽  
Author(s):  
Alisa Kazarina ◽  
Guntis Gerhards ◽  
Elina Petersone-Gordina ◽  
Janis Kimsis ◽  
Ilva Pole ◽  
...  

2002 ◽  
pp. 61-67 ◽  
Author(s):  
L. A. Denisova ◽  
R. G. Maev ◽  
I. V. Matveichuk ◽  
Yu. I. Denisov-Nikolsky ◽  
A. A. Denisov ◽  
...  

2005 ◽  
Vol 26 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Edna S. Miazato Iwamura ◽  
Claudia Regina G.C.M. Oliveira ◽  
Jos?? Arnaldo Soares-Vieira ◽  
Sergio A.B. Nascimento ◽  
Daniel R. Mu??oz

2007 ◽  
Vol 69 (4) ◽  
pp. 409-411 ◽  
Author(s):  
Monika MARTINIAKOVÁ ◽  
Birgit GROSSKOPF ◽  
Radoslav OMELKA ◽  
Mária VONDRÁKOVÁ ◽  
Mária BAUEROVÁ

2014 ◽  
Vol 56 (1) ◽  
Author(s):  
Hana Duranova ◽  
Monika Martiniakova ◽  
Radoslav Omelka ◽  
Birgit Grosskopf ◽  
Ivana Bobonova ◽  
...  

2020 ◽  
Vol 9 ◽  
pp. 342
Author(s):  
K. C. Stamoulis ◽  
P. A. Assimakopoulos ◽  
K. G. Ioannides

Strontium-90 concentration in human bones and teeth, collected in Greece during the period 1992-1996, was measured. One hundred and five bone samples, mainly cancelous (spongy) bone, and 108 samples, involving a total of 896 individual teeth, were processed. Samples were classified according to age and sex of the donors. Radiostrontium concentration in bone samples showed small variations with regard to age or sex, yielding an average value of 30 mBq concentration measurements in teeth evinced a pronounced structure, which clearly reflects contamination from the 1960s atmospheric nuclear weapons tests and the more recent Chernobyl accident. This difference is attributed to the different bone texture of skeletal bones and teeth, the later consisting mainly of compact bone.An age-dependent model for radiostrontium concentration in human bones and teeth was developed, which was able to successfully reproduce the experimental data. Through a fitting process, the model also yielded calcium turnover rates for compact bone as a function of age, as well as an estimate of radiostrontium con- tamination of foodstaffs in Greece for the past four decades.


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