Mechanisms of detoxification of high manganese concentrations by the microalga Chlorella sorokiniana

2021 ◽  
Vol 177 ◽  
pp. S102
Author(s):  
Snežana Vojvodić ◽  
Marina Stanić ◽  
Bernd Zechmann ◽  
Milena Dimitrijević ◽  
Miloš Opačić ◽  
...  
2008 ◽  
Vol 76 (6) ◽  
pp. 2767-2776 ◽  
Author(s):  
David T. Glover ◽  
Susan K. Hollingshead ◽  
David E. Briles

ABSTRACTPrevious studies have suggested that pneumococcal choline binding protein A (PcpA) is important for the full virulence ofStreptococcus pneumoniae, and its amino acid sequence suggests that it may play a role in cellular adherence. PcpA is under the control of a manganese-dependent regulator and is only expressed at low manganese concentrations, similar to those found in the blood and lungs. PcpA expression is repressed under high manganese concentrations, similar to those found in secretions. In this study, we have demonstrated that PcpA elicits statistically significant protection in murine models of pneumonia and sepsis. In the model of pneumonia with each of four challenge strains, statistically fewerS. pneumoniaecells were recovered from the lungs of mice immunized with PcpA and alum versus mice immunized with alum only. The immunizations reduced the median CFU by 4- to 400-fold (average of 28-fold). In the model of sepsis using strain TIGR4, PcpA expression resulted in shorter times to become moribund and subcutaneous immunization with PcpA increased survival times of mice infected with wild-type PcpA-expressing pneumococci.


2014 ◽  
Vol 41 (16) ◽  
pp. 5755-5763 ◽  
Author(s):  
Nina L. Lanza ◽  
Woodward W. Fischer ◽  
Roger C. Wiens ◽  
John Grotzinger ◽  
Ann M. Ollila ◽  
...  

1988 ◽  
Vol 74 (9) ◽  
pp. 1778-1784
Author(s):  
Kyoji KUNISADA ◽  
Hikoya IWAI
Keyword(s):  

Alloy Digest ◽  
2011 ◽  
Vol 60 (8) ◽  

Abstract Wieland-FX9 is a high-manganese bronze alloy that has good strength and is available in numerous cold work tempers related to its minimum tensile strength. This datasheet provides information on composition, physical properties, hardness, elasticity, and tensile properties. It also includes information on corrosion resistance as well as forming, heat treating, and joining. Filing Code: Cu-801. Producer or source: Wieland Metals Inc..


Alloy Digest ◽  
1988 ◽  
Vol 37 (9) ◽  

Abstract UNS G10210 is a carbon steel of relatively high manganese content which increases hardenability and hardness over that of carbon steels of lower manganese. It combines good machinability, good workability (hot or cold) and good weldability. It is used in the annealed, hot-worked, normalized, cold-worked or water-quenched-and-tempered condition for many applications. It may be used in uncarburized applications and for components case-hardened by carburizing. This datasheet provides information on composition, physical properties, hardness, elasticity, and tensile properties as well as fracture toughness. It also includes information on corrosion resistance as well as forming, heat treating, machining, joining, and surface treatment. Filing Code: CS-122. Producer or source: Carbon steel mills.


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