Lower Bone Density on Preoperative Computed Tomography Predicts Periprosthetic Fracture Risk in Total Ankle Arthroplasty

2019 ◽  
Vol 17 (2) ◽  
pp. 113-114
2018 ◽  
Vol 40 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Elizabeth A. Cody ◽  
James R. Lachman ◽  
Elizabeth B. Gausden ◽  
James A. Nunley ◽  
Mark E. Easley

Background: The effect of bone mineral density (BMD) on outcomes from total ankle arthroplasty (TAA) has not been studied. BMD can be estimated by measuring Hounsfield units (HU) on standard computed tomography (CT), which is frequently performed prior to TAA. We aimed to identify whether tibial and talar HU measured from preoperative CT scans were associated with periprosthetic fracture or revision risk in patients undergoing TAA. Methods: A prospectively collected database was used to retrospectively screen all patients undergoing primary TAA. Only patients with a preoperative CT within 1 year of surgery were included. Primary outcomes were periprosthetic fracture and prosthetic revision. HU were measured on axial CT cuts in the distal tibia and talus. Additional patient factors analyzed included age, sex, weight, body mass index (BMI), tobacco use, presence of rheumatoid arthritis, and preoperative deformity. A total of 198 ankles were included, with a mean 2.4 years of follow-up. Results: There were 7 intraoperative and 9 postoperative periprosthetic fractures (3.5% and 4.5%, respectively). Seven patients (3.5%) underwent prosthetic removal or revision. Lower tibial and talar HU, lower weight, and lower BMI were associated with periprosthetic fractures ( P < .05). After controlling for age, sex, and weight, only tibial HU was significantly associated with periprosthetic fracture ( P = .018). All intraoperative fractures occurred in patients with tibial HU less than 200. None of the patient factors analyzed were associated with revision. Conclusions: Lower tibial HU on preoperative CT was strongly associated with periprosthetic fracture risk with TAA. In patients with tibial HU less than 200, surgeons may consider prophylactic internal fixation of the medial malleolus. Level of Evidence: Level III, retrospective cohort study.


2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0003
Author(s):  
Elizabeth Cody ◽  
James Lachman ◽  
Elizabeth Gausden ◽  
James Nunley ◽  
Mark Easley

Category: Ankle Arthritis Introduction/Purpose: Bone density is a modifiable factor which can be addressed prior to elective surgery if necessary. However, its role pertaining to complications of total ankle arthroplasty (TAA) has not been studied. Hounsfield units (HU) can be measured on standard computed tomography (CT) imaging, and have been shown to correlate with bone mineral density measures from dual-energy X-ray absorptiometry (DEXA). There is a precedent for these measurements in the orthopedic literature: different authors have shown that patients with higher vertebral bone density on CT are at lower risk for pedicle screw loosening. We hypothesized that patients with lower bone density, as measured by HU on preoperative CT, or with large preoperative cysts, would be at greater risk for revision and periprosthetic fractures following TAA. Methods: An existing database at the authors’ institution was used to screen all patients who underwent primary TAA. Inclusion criteria included a CT scan within one year prior to surgery. Exclusion criteria included tibial or talar hardware and nonweightbearing status at the time of the CT scan. The primary outcomes were prosthetic revision and periprosthetic fracture. HU were measured on axial CT cuts at 10 mm above the tibial plafond and at 5 mm below the talar dome to approximate the location of bone cuts. HU measurements for 30 patients were made independently by two reviewers in order to establish interrater reliability. Subchondral cysts at least 5 mm in diameter were counted. Additional patient factors analyzed included age, sex, weight, body mass index (BMI), tobacco use, presence of rheumatoid arthritis, preoperative deformity =15°, and pain visual analog scale scores. Results: 198 patients with a mean 2.4 years of follow-up met the inclusion criteria. The intraclass correlation coefficients for tibial and talar HU measurements were both 0.95. Seven patients (3.5%) underwent revision, four for infection, at a mean 1.2 years postoperatively. There were seven intraoperative and nine postoperative periprosthetic fractures (3.5% and 4.5%, respectively). Neither bone density nor cysts were associated with revision (p>.05). Lower tibial and talar HU, lower weight, and lower BMI were all associated with periprosthetic fracture (Table). After controlling for age, sex, and weight, only tibial HU was significantly associated with periprosthetic fractures (p=0.018). All intraoperative fractures occurred in patients with tibial HU <200. Of patients with tibial HU <200, 10 (22%) sustained an intra- or postoperative periprosthetic fracture. Conclusion: Lower tibial and talar bone density on preoperative CT of the ankle was strongly associated with periprosthetic fracture. The low incidence of revision during the relatively short study period limited our ability to analyze effects on revision rates. In patients who have had a preoperative CT, measuring HU represents a quick, simple method of assessing bone density with excellent inter-rater reliability. In patients with tibial HU <200, surgeons may wish to consider prophylactic internal fixation of the medial malleolus.


2020 ◽  
Vol 18 (6) ◽  
pp. 803-810
Author(s):  
Ruth Durdin ◽  
Camille M Parsons ◽  
Elaine Dennison ◽  
Nicholas C Harvey ◽  
Cyrus Cooper ◽  
...  

Abstract Purpose of the Review The aim of this review is to briefly introduce updates in global fracture epidemiology and then to highlight recent contributions to understanding ethnic differences in bone density, geometry and microarchitecture and consider how these might contribute to differences in fracture risk. The review focuses on studies using peripheral quantitative computed tomography techniques. Recent Findings Recent studies have contributed to our understanding of the differences in fracture incidence both between countries, as well as between ethnic groups living within the same country. In terms of understanding the reasons for ethnic differences in fracture incidence, advanced imaging techniques continue to increase our understanding, though there remain relatively few studies. Summary It is a priority to continue to understand the epidemiology, and changes in the patterns of, fracture, as well as the underlying phenotypic and biological reasons for the ethnic differences which are observed.


2020 ◽  
pp. 107110072097609
Author(s):  
Gun-Woo Lee ◽  
Hyoung-Yeon Seo ◽  
Dong-Min Jung ◽  
Keun-Bae Lee

Background: Modern total ankle arthroplasty (TAA) prostheses are uncemented press-fit designs whose stability is dependent on bone ingrowth. Preoperative insufficient bone density reduces initial local stability at the bone-implant interface, and we hypothesized that this may play a role in periprosthetic osteolysis. We aimed to investigate the preoperative bone density of the distal tibia and talus and compare these in patients with and without osteolysis. Methods: We enrolled 209 patients (218 ankles) who underwent primary TAA using the HINTEGRA prosthesis. The overall mean follow-up duration was 66 (range, 24-161) months. The patients were allocated into 2 groups according to the presence of periprosthetic osteolysis: the osteolysis group (64 patients, 65 ankles) and nonosteolysis group (145 patients, 153 ankles). Between the 2 groups, we investigated and compared the radiographic outcomes, including the Hounsfield unit (HU) value around the ankle joint and the coronal plane alignment. Results: HU values of the tibia and talus measured at 5 mm from the reference points were higher than those at 10 mm in each group. However, comparing the osteolysis and nonosteolysis groups, we found no significant intergroup difference in HU value at every measured level in the tibia and talus ( P > .05). Concerning the coronal plane alignment, there were no significant between-group differences in the tibiotalar and talar tilt angles ( P > .05). Conclusions: Patients with osteolysis showed similar preoperative bone density of the distal tibia and talus compared with patients without osteolysis. Our results suggest that low bone density around the ankle joint may not be associated with increased development of osteolysis. Level of Evidence: Level III, retrospective cohort study.


2020 ◽  
Vol 5 (4) ◽  
pp. 2473011420S0041
Author(s):  
Bailey J. Ross ◽  
Ian Savage-Elliott ◽  
Victor Wu ◽  
Ramon F. Rodriguez

Category: Ankle Arthritis; Ankle Introduction/Purpose: Ankle arthrodesis (AA) has historically been the gold standard for operative management of end-stage ankle osteoarthritis (OA). Recent increases in utilization of total ankle arthroplasty (TAR) have been observed secondary to new implant designs, improved surgical technique, and favorable functional outcomes. However, there is minimal data comparing clinical complications between the two procedures. The purpose of this study was to compare incidences of postoperative joint and systemic complications for patients that received primary AA vs. TAR for primary ankle osteoarthritis between 2007-2017 using a comprehensive Medicare database. Methods: A retrospective review of patients that received primary AA or TAR was performed using the PearlDiver database (Fort Wayne, IN). All patients and associated complications were identified using ICD-9/ICD-10 and CPT codes. Patients with a history of ankle fracture, prior AA/TAR, or active ankle infection during the index procedure were excluded. Demographic data and overall joint complication rates were compared at 90-days, 1-year, and 2-years postoperatively using a Chi-Square test. Postoperative rates of subtalar fusion, prosthetic joint infection, hardware removal, periprosthetic fracture, and systemic complications were compared using logistic regression. Statistical significance was set at p < 0.05. Results: A total of 1,580 patients received operative management of primary ankle OA: 1,100 (70%) patients received AA and 480 (30%) patients received TAR. The overall joint complication rate was higher in the AA group at 90-days (30% vs. 17%, p < 0.001), 1-year (36% vs. 21%, p < 0.001), and 2-years (38% vs. 22%, p < 0.001) post-discharge. AA patients were more likely to have a subsequent subtalar fusion at 90-days (OR 4.49), 1-year (OR 5.10), and 2-years (OR 5.36) post-discharge, as well as periprosthetic fracture at 1-year (OR 1.69) and 2-years (OR 1.77). Hardware removal was less likely for AA patients at 90-days (OR 0.43), 1-year (OR 0.41), and 2-years (OR 0.43). Neither group was more likely to develop systemic complications postoperatively. Conclusion: The present study found that AA patients have higher incidences of major joint complications in both the short- term and mid-term. Patients that received AA were more likely to have a subsequent subtalar fusion and sustain a periprosthetic fracture. Relative to TAR patients, a greater proportion of these patients were under the age of 65, obese, had diabetes, and used tobacco. TAR patients were more likely to have hardware removal post-discharge. Further study is warranted to better quantify patient selection for AA vs. TAR and trend the long-term complications of these procedures.


2013 ◽  
Vol 42 (11) ◽  
pp. 1507-1513 ◽  
Author(s):  
Ia Kohonen ◽  
Helka Koivu ◽  
Tero Vahlberg ◽  
Heli Larjava ◽  
Kimmo Mattila

2005 ◽  
Vol 38 (10) ◽  
pp. 36-37
Author(s):  
KERRI WACHTER
Keyword(s):  

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