Determinants of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Beyond Pulmonary Vascular Resistance

2019 ◽  
Vol 38 (4) ◽  
pp. S485
Author(s):  
A. Chaturvedi ◽  
M. Naik ◽  
A.A. Joshi ◽  
J. PO ◽  
T. Meeran ◽  
...  
2020 ◽  
Vol 10 (5) ◽  
pp. 1659-1674
Author(s):  
Chakradhari Inampudi ◽  
Ryan J. Tedford ◽  
Anna R. Hemnes ◽  
Georg Hansmann ◽  
Harm-Jan Bogaard ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Marc A. Simon ◽  
Michael R. Pinsky

Right ventricular (RV) dysfunction is the main cause of death in pulmonary arterial hypertension (PAH). Our understanding of the pathophysiology of RV dysfunction is limited but improving. Methods to better diagnose RV dysfunction earlier and treatments specifically designed to minimize or reverse the remodeling process are likely to improve outcomes. We review the current understanding of RV dysfunction in chronic pressure overload and introduce some novel insights based on recent investigations into pathophysiology, diagnosis, and treatment.


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