Soluble Epoxide Hydrolase Inhibitors Attenuate Cardiomyocyte Hypertrophy and Cardiofibroblast Collagen Synthesis via JNK and NFκB Pathway

Cardiomyocyte Hypertrophy ◽

Nfκb Pathway

Faculty Opinions recommendation of Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1046256.496189 ◽

2006 ◽

Author(s):

Deanna Kroetz

Keyword(s):

Epoxide Hydrolase ◽

Inflammatory Drugs ◽

Anti Inflammatory

Synthesis and Properties of N-[R-Adamantan-1(2)-yl]-N′-(2-fluorophenyl)ureas—Target-Oriented Soluble Epoxide Hydrolase Inhibitors

Russian Journal of Organic Chemistry ◽

10.1134/s1070428018090063 ◽

2018 ◽

Vol 54 (9) ◽

pp. 1307-1312 ◽

Cited By ~ 3

Author(s):

V. V. Burmistrov ◽

G. M. Butov

Keyword(s):

Epoxide Hydrolase ◽

Dietary soluble epoxide hydrolase inhibitors effect on hepatic gene expression of lipid metabolism in hamsters

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.479.53 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Glenn Bartley ◽

Hsing‐Ju Tsai ◽

Yun‐Jeong Hong ◽

Bruce Hammock ◽

Wallace Yokoyama

Keyword(s):

Gene Expression ◽

Lipid Metabolism ◽

Epoxide Hydrolase ◽

Hepatic Gene Expression ◽

Identifying Simultaneous Matrix Metalloproteinases/Soluble Epoxide Hydrolase Inhibitors

The FASEB Journal ◽

10.1096/fasebj.29.1_supplement.781.1 ◽

2015 ◽

Vol 29 (S1) ◽

Author(s):

Ahmed El‐Sherbeni ◽

Rabia Bhatti ◽

Ayman El‐Kadi

Keyword(s):

Matrix Metalloproteinases ◽

Epoxide Hydrolase ◽

A high‐throughput fluorescence polarization assay for the determination of Kd for soluble epoxide hydrolase inhibitors

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.479.21 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Richard H. Ingraham ◽

Rachel R. Kroe ◽

Maurice M. Morelock ◽

John R. Proudfoot ◽

Anne B. Eldrup ◽

...

Keyword(s):

High Throughput ◽

Fluorescence Polarization ◽

Epoxide Hydrolase ◽

Fluorescence Polarization Assay

Synthesis and properties of 1-(R-adamant-1-yl)-3-(1-propionylpiperidin-4-yl)ureas and 4-({4-[3-(R-adamant-1-yl)ureido]cyclohexyl}oxy)benzoic acids, efficient target-oriented human soluble epoxide hydrolase inhibitors

Russian Chemical Bulletin ◽

10.1007/s11172-017-1961-y ◽

2017 ◽

Vol 66 (10) ◽

pp. 1876-1880 ◽

Cited By ~ 5

Author(s):

G. M. Butov ◽

V. V. Burmistrov ◽

D. V. Danilov

Keyword(s):

Epoxide Hydrolase ◽

Benzoic Acids ◽

In vitro and in silico investigation of anthocyanin derivatives as soluble epoxide hydrolase inhibitors

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2018.02.061 ◽

2018 ◽

Vol 112 ◽

pp. 961-967 ◽

Cited By ~ 5

Author(s):

Jang Hoon Kim ◽

In Sook Cho ◽

Jaihyuk Ryu ◽

Ji Sun Lee ◽

Jong Seong Kang ◽

...

Keyword(s):

In Silico ◽

Epoxide Hydrolase ◽

Discovery of Novel Soluble Epoxide Hydrolase Inhibitors as Potent Vasodilators

Scientific Reports ◽

10.1038/s41598-018-32449-4 ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 7

Author(s):

Neetika Tripathi ◽

Sarvesh Paliwal ◽

Swapnil Sharma ◽

Kanika Verma ◽

Ritika Gururani ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Quantitative Structure Activity Relationships Study of Soluble Epoxide Hydrolase Inhibitors Using MLR, ANN, CoMFA and CoMSIA Methods

ChemistrySelect ◽

10.1002/slct.201900471 ◽

2019 ◽

Vol 4 (20) ◽

pp. 6348-6353

Author(s):

Maryam Nazari ◽

Sayyed Abbas Tabatabai ◽

Elham Rezaee

Keyword(s):

Epoxide Hydrolase ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.08.054 ◽

2013 ◽

Vol 23 (21) ◽

pp. 5975-5979 ◽

Cited By ~ 7

Author(s):

Yuko Kato ◽

Nobuhiro Fuchi ◽

Hajime Saburi ◽

Yutaka Nishimura ◽

Ayano Watanabe ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Active Drug ◽

Urea Derivatives ◽

Drug Candidates ◽

Orally Active