scholarly journals Risk factors of recurrent acute pancreatitis and progression to chronic pancreatitis after the first attack of acute pancreatitis

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S523-S524
Author(s):  
J.H. Cho ◽  
E.J. Kim ◽  
Y.J. Kim ◽  
Y.S. Kim
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Chronic Pancreatitis ◽  
Recurrent Acute Pancreatitis

Mo1253 - Risk Factors of Recurrent Acute Pancreatitis and Progression to Chronic Pancreatitis after the first Attack of Acute Pancreatitis

2018 ◽  
Vol 154 (6) ◽  
pp. S-721-S-722
Author(s):  
Joonhwan Kim ◽  
Jae Hee Cho ◽  
Eui Joo Kim ◽  
YeonSuk Kim ◽  
Hee Man Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Chronic Pancreatitis ◽  
Recurrent Acute Pancreatitis

scholarly journals Physician-Controlled Wire-Guided Cannulation of the Minor Papilla

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
John T. Maple ◽  
Lilah Mansour ◽  
Tarek Ammar ◽  
Michael Ansstas ◽  
Gregory A. Coté ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Chronic Pancreatitis ◽  
Stent Placement ◽  
Case Series ◽  
Pancreatic Stent ◽  
Tertiary Referral ◽  
Recurrent Acute Pancreatitis ◽  
Minor Papilla ◽  
Safe Technique

Background. Minor papilla (MiP) cannulation is frequently performed using specialized small-caliber accessories. Outcomes data for MiP cannulation with standard-sized accessories are lacking. Methods. This is a case series describing MiP cannulation outcomes in consecutive patients treated by two endoscopists between July 2005 and November 2008 at two tertiary referral centers. MiP cannulation was attempted using a 4.4 Fr tip sphincterotome loaded with a , 260 cm hydrophilic-tip guidewire, using a wire-guided technique under physician control. Results. 25 patients were identified (14 women, mean age 45). Procedure indications included recurrent acute pancreatitis in 16 patients (64%) and chronic pancreatitis in 2 (8%), among other indications. MiP cannulation was successful in 24 patients (96%). Sphincterotomy followed by pancreatic stent placement was performed in 21 patients (84%). Mild post-ERCP pancreatitis occurred in 3 patients (12%). Conclusion. Physician-controlled wire-guided MiP cannulation using a 4.4 Fr sphincterotome and guidewire is an effective and safe technique.

Recurrent acute pancreatitis can be considered as early chronic pancreatitis: a meta-analysis of 21,186 patients

Pancreatology ◽  
2019 ◽  
Vol 19 ◽  
pp. S44
Author(s):  
Alexandra Soós ◽  
Péter Hegyi ◽  
Zsolt Szakács ◽  
Alexandra Mikó ◽  
Péter Mátrai ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Chronic Pancreatitis ◽  
Meta Analysis ◽  
Recurrent Acute Pancreatitis

PREVALENCE OF SPINK 1 AND CASR GENE MUTATIONS IN ACUTE AND RECURRENT ACUTE PANCREATITIS : A STUDY FROM CENTRAL INDIA

2021 ◽  
pp. 62-65
Author(s):  
Mohd Talha Noor ◽  
Rahul Sudan ◽  
Vipin Goyal ◽  
Susmit Kosta ◽  
Ravindra Kumar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Gene Mutation ◽  
Genetic Factors ◽  
Receptor Gene ◽  
Gene Mutations ◽  
Recurrent Acute Pancreatitis ◽  
Casr Gene ◽  
Increased Risk ◽  
Spink 1

Background: Genetic factors may play an important role in the pathogenesis of acute pancreatitis. It has been observed in various studies that the presence of risk factors alone like alcohol abuse or gall bladder stones does not lead to attacks of pancreatitis in all the patients. This leads to assumption that genetic factors may decrease the threshold for the development of pancreatitis in presence of one or more risk factors. We observed that there is a paucity of data regarding the role of genetics in acute pancreatitis (AP) and recurrent acute pancreatitis (RAP) in our part of the world and we aimed at studying the prevalence of genetic mutations in such patients. Methods: Our study intended to nd the prevalence of SPINK1 N34S (Serine protease inhibitor kazal type 1) and CaSR (Calcium sensing receptor) gene mutations in patients of AP and RAP. A total of 50 patients and 25 age and gender matched controls entered our study. Blood samples were obtained from all the cases and controls for routine investigations and genetic analysis. SPINK 1 N34S and CaSR gene mutation studies were done in all the patients and controls. Results: Alcohol (64%) followed by gallbladder stone disease (20%) was the most common aetiology of pancreatitis. SPINK 1 N34S mutation was present in 21 patients and 2 controls whereas CaSR gene mutation was present in 13 patients and 2 controls. Patients with SPINK 1 N34S and CaSR gene mutations were younger than the patients without these mutations. Prevalence of both SPINK1 N34S and CaSR gene mutations was higher in patients of RAP than AP. These mutations were not associated with aetiology or severity of pancreatitis. Conclusion: The prevalence SPINK 1 N34S and CaSR gene mutations was higher in patients of AP and RAP. Identication of these mutations in patients of AP can help in the identication of patients who are at increased risk of recurrent attacks of AP

scholarly journals Risk factors of recurrent acute pancreatitis after conservative treatment in pediatric population: a single-center study

2021 ◽  
Vol 4 (1) ◽  
pp. e000209
Author(s):  
Qipeng Zheng ◽  
Xueqiang Yan ◽  
Liang Ge ◽  
Shujian Zhang ◽  
Yan Sun ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Diagnostic Criteria ◽  
Pediatric Population ◽  
Treatment Strategies ◽  
First Episode ◽  
Initial Attack ◽  
Recurrent Acute Pancreatitis ◽  
Fasting Time ◽  
Independent Risk Factors

BackgroundAlthough complete resolution and recovery occurs in most children with an initial attack of acute pancreatitis (AP), a subset of children may progress to recurrent AP (RAP). RAP has serious effects to the individual and the socioeconomic burden. The aim of this project was to identify the independent risk factors for pediatric RAP so as to provide evidence for its prevention, early diagnosis and treatment.MethodsA retrospective cohort study of children discharged from Tianjin Children’s Hospital from June 2017 to January 2020 was performed. Demographic and clinical variables, treatment strategies, clinical course and outcomes were collected. Independent risk factors of RAP were identified using the logistic regression model.ResultsOf the total 96 enrolled children, 30 (31.3%) developed RAP during the follow-up period. The majority (27/30, 90%) of the children with AP developed RAP within 6 months of their first AP attack. The presence of systemic inflammatory response syndrome (SIRS) [odds ratio (OR)=6.652, 95% confidence interval (CI) 1.989 to 22.247], fasting time (OR=1.267, 95% CI 1.104 to 1.583), whether meet all three AP diagnostic criteria (OR=7.438, 95% CI 1.346 to 41.103) and abnormal amylase/lipase value on the seventh day of hospitalization (OR=3.601, 95% CI 0.972 to 13.342) were independent risk factors of RAP in children.ConclusionsMost children who developed RAP had progressed within 6 months after their first episode of AP. RAP was more common in children who met all three AP diagnostic criteria at initial attack and in children with SIRS, long fasting time and abnormal amylase/lipase value on the seventh day of hospitalization.

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