scholarly journals B-PO04-156 TEMPORAL TRENDS IN THE INCIDENCE AND CHARACTERISTICS OF SUDDEN CARDIAC DEATH AMONG YOUNG IN NORTHERN FINLAND DURING 1998-2017

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S342
Author(s):  
Lauri Holmström ◽  
Mira Anette Haukilahti ◽  
Juha Vähätalo ◽  
Lasse Pakanen, Janna Pauliina Kauppila ◽  
Henrik Appel ◽  
...  
BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e020865
Author(s):  
Niilo R I Ryti ◽  
M Juhani Junttila ◽  
Harri Antikainen ◽  
Marja-Leena Kortelainen ◽  
Heikki V Huikuri ◽  
...  

ObjectiveTo test the a priori hypothesis that the association between cold spells and ischaemic sudden cardiac death (SCD) is modified by the severity of coronary stenosis.MethodsThe home coordinates of 2572 autopsy-verified cases of ischaemic SCD aged ≥35 in the Province of Oulu, Finland, were linked to 51 years of weather data. Cold spell was statistically defined for each home address as unusually cold weather pertinent to the location and time of year. We estimated the occurrence of cold spells during the hazard period (7 days preceding death) and reference periods (the same calendar days over 51 years) in a case-crossover setting applying conditional logistic regression, controlling for temporal trends and stratifying by severity of coronary stenosis.ResultsThe association between cold spells and ischaemic SCD was stronger among patients with 75%–95% stenosis (OR 2.03; 95% CI 1.31 to 3.17), and weaker to non-existent among patients with <75% stenosis (OR 0.97; 95% CI 0.37 to 2.55) or coronary total occlusion (100% stenosis) (OR 1.01; 95% CI 0.52 to 1.96). Lack of calcium-channel blockers and statin therapy seemed to accentuate the role of stenosis during cold spells.ConclusionsWe provide evidence that the association between cold spells and ischaemic SCD is modified by the severity of coronary stenosis. The findings suggest that disturbances in coronary circulation play part in the pathogenesis of SCD during cold weather.


2017 ◽  
Vol 26 (8) ◽  
pp. 808-816 ◽  
Author(s):  
Jia-Li Feng ◽  
Lee Nedkoff ◽  
Matthew Knuiman ◽  
Christopher Semsarian ◽  
Jodie Ingles ◽  
...  

Circulation ◽  
2004 ◽  
Vol 110 (5) ◽  
pp. 522-527 ◽  
Author(s):  
Caroline S. Fox ◽  
Jane C. Evans ◽  
Martin G. Larson ◽  
William B. Kannel ◽  
Daniel Levy

Heart Rhythm ◽  
2014 ◽  
Vol 11 (10) ◽  
pp. 1684-1690 ◽  
Author(s):  
Kairav Vakil ◽  
Ziad Taimeh ◽  
Alok Sharma ◽  
Kashan Syed Abidi ◽  
Monica Colvin ◽  
...  

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318881
Author(s):  
Frederik Nybye Ågesen ◽  
Thomas Hadberg Lynge ◽  
Paul Blanche ◽  
Jytte Banner ◽  
Eva Prescott ◽  
...  

ObjectiveMore knowledge about the development of sudden cardiac death (SCD) in the general population is needed to develop meaningful predictors of SCD. Our aim with this study was to estimate the incidence of SCD in the general population and examine the temporal changes, demographics and clinical characteristics.MethodsAll participants in the Copenhagen City Heart Study were followed from 1993 to 2016. All death certificates, autopsy reports and national registry data were used to identify all cases of SCD.ResultsA total of 14 562 subjects were included in this study. There were 8394 deaths with all information available, whereof 1335 were categorised as SCD. The incidence of SCD decreased during the study period by 41% for persons aged 40–90 years, and the standardised incidence rates decreased from 504 per 100 000 person-years (95% CI 447 to 569) to 237 per 100 000 person-years (95% CI 195 to 289). The incidence rate ratio of SCD between men and women ≤75 years was 1.99 (95% CI 1.62 to 2.46). The proportion of SCD of all cardiac deaths decreased during the observation period and decreased with increasing age. Men had more cardiovascular comorbidities (OR 1.34, 95% CI 1.07 to 1.68, p<0. 01), and SCD was the first registered manifestation of cardiac disease in 50% of all cases.ConclusionThe incidence of SCD in the general population has declined significantly during the study period but should be further investigated for more recent variations as well as novel risk predictors for persons with low to medium risk of SCD.


Resuscitation ◽  
2019 ◽  
Vol 136 ◽  
pp. 1-7 ◽  
Author(s):  
Mony Shuvy ◽  
Feng Qiu ◽  
Geoffrey Lau ◽  
Maria Koh ◽  
Paul Dorian ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017398 ◽  
Author(s):  
Niilo R I Ryti ◽  
Elina M S Mäkikyrö ◽  
Harri Antikainen ◽  
Eeva Hookana ◽  
M Juhani Junttila ◽  
...  

ObjectiveTo testa priorihypothesis of an association between season-specific cold spells and sudden cardiac death (SCD).MethodsWe conducted a case–crossover study of 3614 autopsy-verified cases of SCD in the Province of Oulu, Finland (1998–2011). Cold spell was statistically defined by applying an individual frequency distribution of daily temperatures at the home address during the hazard period (7 days preceding death) and 50 reference periods (same calendar days of other years) for each case using the home coordinates. Conditional logistic regression was applied to estimate ORs for the association between the occurrence of cold spells and the risk of SCD after controlling for temporal trends.ResultsThe risk of SCD was associated with a preceding cold spell (OR 1.33; 95% CI 1.00, 1.78). A greater number of cold days preceding death increased the risk of SCD approximately 19% per day (OR 1.19; 95% CI 1.07 to 1.32). The association was strongest during autumn (OR 2.51; 95% CI 1.27 to 4.96) and winter (OR 1.70; 95% CI 1.13 to 2.55) and lowest during summer (OR 0.42; 95% CI 0.15 to 1.18) and spring (OR 0.89; 95% CI 0.45 to 1.79). The association was stronger for ischaemic (OR 1.55; 95% CI 1.12 to 2.13) than for non-ischaemic SCD (OR 0.68; 95% CI 0.32 to 1.45) verified by medicolegal autopsy.ConclusionsOur results indicate that there is an association between cold spells and SCD, that this association is strongest during autumn, when the weather event is prolonged, and with cases suffering ischaemic SCD. These findings are subsumed with potential prevention via weather forecasting, medical advice and protective behaviour.


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