Relation of coronary culprit lesion morphology determined by optical coherence tomography and cardiac outcomes to preinfarction angina in patients with acute myocardial infarction

2018 ◽  
Vol 269 ◽  
pp. 356-361 ◽  
Author(s):  
Nobuaki Kobayashi ◽  
Noritake Hata ◽  
Masafumi Tsurumi ◽  
Yusaku Shibata ◽  
Hirotake Okazaki ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Culprit Lesion ◽  
Cardiac Outcomes ◽  
Lesion Morphology

Abstract 17859: Gender Difference in Underlying Plaque Morphology of the Culprit Lesion in Patients with Acute Myocardial Infarction: an in vivo Optical Coherence Tomography Study

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Sining Hu ◽  
Haibo Jia ◽  
Tsunenari Soeda ◽  
Yoshiyasu Minami ◽  
Rocco Vergallo ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Optical Coherence Tomography ◽  
Gender Difference ◽  
Plaque Rupture ◽  
Morphological Characteristics ◽  
Plaque Morphology ◽  
Optical Coherence ◽  
Culprit Lesion

Introduction: Autopsy studies in sudden cardiac death subjects showed female had higher incidence of erosion. However, the incidence of erosion in patients with acute myocardial infarction (AMI) has not been systematically studied. Hypothesis: This study was to study the gender difference in the prevalence and morphological characteristics of the culprit lesion in patients with AMI using intravascular optical coherence tomography (OCT). Methods: A total of 79 patients (65 male and 14 female) with AMI who underwent pre-intervention OCT imaging of the culprit lesion were included. Results: Baseline characteristics between the two groups were similar. In OCT findings, the incidence of thin-cap fibroatheroma (TCFA) was slightly lower and the fibrous cap thickness was slightly thicker in female than in male, but the differences were not significant. Defining underlying plaque morphology by genders, plaque erosion was more prevalent in female than in male, whereas plaque rupture was more frequent in male (Table). Conclusions: Erosion was the most frequent cause of AMI in female patients, whereas plaque rupture is the predominant underlying pathology of AMI in male patients.

Association between pre-infarction angina and culprit-lesion morphology in patients with ST-segment elevation myocardial infarction: an optical coherence tomography study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Y Wang ◽  
Z Sheng ◽  
J Li ◽  
Y Tan ◽  
P Zhou ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Optical Coherence Tomography ◽  
Plaque Rupture ◽  
Funding Source ◽  
Optical Coherence ◽  
Culprit Lesion ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Lesion Morphology

Abstract Background Previous studies reported the cardiac protection effect of pre-infarction angina (PIA) in patients with acute myocardial infarction (AMI). However, the association between PIA and culprit plaques characteristics in AMI patients through optical coherence tomography (OCT)assessment remains unclear. Purpose We sought to identify culprit-plaque morphology associated with PIA in patients with ST-segment elevation myocardial infarction (STEMI) using OCT. Methods A total of 279 STEMI patients who underwent intravascular OCT of culprit-lesion were included. Baseline clinical data and culprit-plaque characteristics were compared between the PIA group the non-PIA group. Results Patients with PIA represented 54.8% of the study population (153 patients). No differences were observed in clinical and angiographic data between two groups, except STEMI onset with exertion was significantly less common in PIA group (24.2% versus 40.5%, P=0.004). Patients with PIA exhibited a significantly lower incidence of plaque rupture (40.5% versus 61.9%, P<0.001) and lipid-rich plaques (48.4% versus 69.0%, P=0.001). The thin-cap fibroatheroma (TCFA) prevalence was lower in PIA group, presenting a thicker fibrous cap thickness, although statistically significant differences were not observed (20.3% versus 30.2%, P=0.070; 129.1±92.0μm versus 111.4±78.1μm, P=0.088; respectively). Multivariate logistic regression analysis indicated that PIA was an independent negative predictor for plaque rupture (odds ratio: 0.44, 95% confidence interval: 0.268–0.725, P=0.001). Conclusion STEMI patients with PIA showed a significantly lower prevalence of plaque rupture and lipid-rich plaques in culprit-lesion than non-PIA group, implying different mechanisms of STEMI attack. Flow chart + Bar graphs of OCT findings Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): Association between pre-infarction angina and culprit-lesion morphology in patients with ST-segment elevation myocardial infarction: An optical coherence tomography study

Culprit lesion morphology in patients with ST-segment elevation myocardial infarction assessed by optical coherence tomography

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kirstine Nørregaard Hansen ◽  
Lisbeth Antonsen ◽  
Akiko Maehara ◽  
Michael Maeng ◽  
Julia Ellert ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Culprit Lesion ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Lesion Morphology

scholarly journals Assessment of Culprit Lesion of Optical Coherence Tomography in Patients With Acute Myocardial Infarction: a Case Report

2020 ◽  
Vol 23 (1) ◽  
pp. E061-E062
Author(s):  
Han Joon Bae
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Culprit Lesion ◽  
Severe Stenosis ◽  
Stenotic Lesion ◽  
Fibrous Cap ◽  
Imaging Tool ◽  
The Difference

In general, patients with acute myocardial infarction (AMI) have severe stenosis secondary to a superimposed thrombus at the event. Optical coherence tomography (OCT) is a useful imaging tool for patients with AMI. This allows us to identify the site of ruptured plaque, erosion of fibrous cap, and characteristics of stenotic lesion. In this case, we present the difference of the ruptured cavity and obstructed lesion.

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