In vitro mechanisms of interleukin-8-mediated responses of human gingival epithelial cells to Candida albicans infection

2006 ◽  
Vol 296 (4-5) ◽  
pp. 301-311 ◽  
Author(s):  
Hiroshi Egusa ◽  
Hiroki Nikawa ◽  
Seicho Makihira ◽  
Hirofumi Yatani ◽  
Taizo Hamada
2005 ◽  
Vol 73 (1) ◽  
pp. 622-626 ◽  
Author(s):  
Hiroshi Egusa ◽  
Hiroki Nikawa ◽  
Seicho Makihira ◽  
Anahid Jewett ◽  
Hirofumi Yatani ◽  
...  

ABSTRACT Increased induction of interleukin 8 (IL-8) and intercellular adhesion molecule 1 (ICAM-1) by oral epithelial cells may play a role in the host defense mechanism in oropharyngeal candidiasis; however, little is known about the expression feature of these molecules on human gingival epithelial cells (HGECs) during Candida albicans infection. In this report we present evidence that neutralization with antibody against ICAM-1 inhibited both the adherence of C. albicans to HGECs and the Candida-induced production of IL-8, suggesting a role for ICAM-1 in recognition and signaling in HGECs to express IL-8 upon infection with C. albicans.


2011 ◽  
Vol 10 (2) ◽  
pp. 77-82 ◽  
Author(s):  
Yoko Tanaka ◽  
Lin Zhang ◽  
Tonami Ikuta ◽  
Joutaro Omori ◽  
Hirotaka Omine ◽  
...  

2011 ◽  
Vol 10 (1) ◽  
pp. 43-49
Author(s):  
Katsumasa Tsushima ◽  
Ying Li ◽  
Lin Zhang ◽  
Noboru Kuboyama ◽  
Yoshimitsu Abiko

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