Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla

Central Giant Cell Granuloma (CGCG) is an intrabony lesion showing cellular fibrosis with numerous foci of haemorrhage, woven bone trabeculae and multinucleated giant cells. It is more commonly found in the mandible than maxilla. Among all benign tumours of jaw, it accounts for less than 7%. According to the reports, in approximately 48% cases, it is diagnosed in the first two decades of life and in almost 60% cases, before 30 years of age. This paper presents a case of CGCG involving the mandibular left anterior region of a female patient with clinical, radiological, histopathological and surgical aspects of the lesion. Key Words- Central Giant Cell Granuloma (CGCG), CONSERVATIVE SURGICAL ENUCLEATION

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Central giant cell granuloma in a paediatric maxilla: surgical management and a novel gene translocation

Journal of Oral and Maxillofacial Surgery Medicine and Pathology ◽

10.1016/j.ajoms.2021.06.003 ◽

2021 ◽

Author(s):

Jason Diab ◽

Gwendolyn Huang ◽

Rebecca Morrow ◽

Lynette Moore ◽

Sam Gue ◽

...

Keyword(s):

Giant Cell ◽

Surgical Management ◽

Giant Cell Granuloma ◽

Central Giant Cell Granuloma ◽

Novel Gene ◽

Gene Translocation

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Non-surgical management of central giant cell granuloma with calcitonin nasal spray in an 8-year-old patient: Radiographic presentation

International Journal of Oral Health Dentistry ◽

10.18231/j.ijohd.2020.064 ◽

2021 ◽

Vol 6 (4) ◽

pp. 312-315

Author(s):

Amina Sultan ◽

◽

Ravi S Batra

Keyword(s):

Giant Cell ◽

Surgical Management ◽

Nasal Spray ◽

Giant Cell Granuloma ◽

Central Giant Cell Granuloma ◽

Calcitonin Nasal Spray ◽

Radiographic Presentation

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Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study

Head and Neck Pathology ◽

10.1007/s12105-019-01053-x ◽

2019 ◽

Vol 14 (2) ◽

pp. 497-502 ◽

Cited By ~ 2

Author(s):

Raíssa Pinheiro de Mendonça ◽

Geovanni Pereira Mitre ◽

Flavio Henrique Real ◽

Maria Sueli da Silva Kataoka ◽

Sérgio de Melo Alves Júnior ◽

...

Keyword(s):

Giant Cell ◽

Giant Cell Granuloma ◽

Central Giant Cell Granuloma ◽

Intralesional Corticosteroid ◽

Long Term Follow Up ◽

Corticosteroid Injections

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Management of recurrent central giant cell granuloma of mandible using intralesional corticosteroid with long-term follow-up

BMJ Case Reports ◽

10.1136/bcr-2020-237200 ◽

2020 ◽

Vol 13 (9) ◽

pp. e237200

Author(s):

Kumar Nilesh ◽

Anuj Dadhich ◽

Rahul Patil

Keyword(s):

Giant Cell ◽

Osteolytic Lesion ◽

Giant Cell Granuloma ◽

Central Giant Cell Granuloma ◽

Intralesional Corticosteroid ◽

Ablative Surgery ◽

Long Term Follow Up ◽

Intralesional Injections

Central giant cell granuloma (CGCG) is an expansile osteolytic lesion of the jawbone. Conventional treatment of CGCG is surgical and vary from simple curettage to more aggressive resection of the jaw. However, surgical management is associated with drawbacks including requirement of hospitalisation and general anaesthesia, damage to vital anatomic structures and continuity defect of the mandible requiring reconstruction surgery. Use of intralesional injections of corticosteroid for the management of CGCG have been inconsistently used as an alternative non-surgical method of management of CGCG with varying success. While the use of such conservative modality over ablative surgery can significantly reduce postoperative morbidity, follow-up of such cases for a long period is important to study the possible recurrence. This paper reports successful treatment of a recurrent CGCG of posterior mandible by intralesional administration of triamcinolone acetonide in a 27-year old female patient, with long-term follow-up of 10 years.

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