Hydrophilic-hydrophobic polymer blend for modulation of crystalline changes and molecular interactions in solid dispersion

2016 ◽  
Vol 513 (1-2) ◽  
pp. 148-152 ◽  
Author(s):  
Hai Van Ngo ◽  
Phuc Kien Nguyen ◽  
Toi Van Vo ◽  
Wei Duan ◽  
Van-Thanh Tran ◽  
...  
Keyword(s):  
Polymer Blend ◽  
Solid Dispersion ◽  
Molecular Interactions ◽  
Hydrophobic Polymer

SN-38 loading capacity of hydrophobic polymer blend nanoparticles: formulation, optimization and efficacy evaluation

2016 ◽  
Vol 43 (3) ◽  
pp. 502-510 ◽  
Author(s):  
Simona Dimchevska ◽  
Nikola Geskovski ◽  
Gjorgji Petruševski ◽  
Marina Chacorovska ◽  
Riste Popeski-Dimovski ◽  
...  
Keyword(s):  
Polymer Blend ◽  
Loading Capacity ◽  
Efficacy Evaluation ◽  
Formulation Optimization ◽  
Hydrophobic Polymer

Rotary Beveling for In Situ Thin-Section Microscopy of Cell Cultures

1981 ◽  
Vol 39 ◽  
pp. 550-551
Author(s):  
Dean A. Handley ◽  
Jack T. Alexander ◽  
Shu Chien
Keyword(s):  
Cell Growth ◽  
Cell Cultures ◽  
Molecular Interactions ◽  
Convenient Method ◽  
Petri Dish ◽  
Simple Method ◽  
Thin Section Microscopy ◽  
Thin Sectioning ◽  
Organic Fluids

In situ preparation of cell cultures for ultrastructural investigations is a convenient method by which fixation, dehydration and embedment are carried out in the culture petri dish. The in situ method offers the advantage of preserving the native orientation of cell-cell interactions, junctional regions and overlapping configurations. In order to section after embedment, the petri dish is usually separated from the polymerized resin by either differential cryo-contraction or solvation in organic fluids. The remaining resin block must be re-embedded before sectioning. Although removal of the petri dish may not disrupt the native cellular geometry, it does sacrifice what is now recognized as an important characteristic of cell growth: cell-substratum molecular interactions. To preserve the topographic cell-substratum relationship, we developed a simple method of tapered rotary beveling to reduce the petri dish thickness to a dimension suitable for direct thin sectioning.

The absorption characteristics of bifendate solid dispersion in rat intestinal tissue

2009 ◽  
Vol 00 (00) ◽  
pp. 090810023429058-9
Author(s):  
Juan Cheng ◽  
Zheng Hong Wu ◽  
Qineng Neng Ping ◽  
Bogang Wang ◽  
Junjun Lu
Keyword(s):  
Solid Dispersion ◽  
Intestinal Tissue ◽  
Absorption Characteristics

Solid dispersion of valsartan for solubility improvement using β-cyclodextrin

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
Sapkal SB ◽  
Shinde SA ◽  
Darakhe RA ◽  
Shrikhande VN
Keyword(s):  
Solid Dispersion ◽  
Solubility Improvement
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