Formulation of simvastatin chitosan nanoparticles for controlled delivery in bone regeneration: Optimization using Box-Behnken design, stability and in vivo study

2020 ◽  
Vol 577 ◽  
pp. 119038 ◽  
Author(s):  
Wisam Khalaf Delan ◽  
Mai Zakaria ◽  
Basma Elsaadany ◽  
Aliaa N. ElMeshad ◽  
Wael Mamdouh ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Chitosan Nanoparticles ◽  
Controlled Delivery ◽  
In Vivo Study ◽  
Box Behnken Design

scholarly journals Guided bone regeneration of chronic non‐contained bone defects using a volume stable porous block TiO2 scaffold: An experimental in vivo study

2021 ◽  
Author(s):  
Minh Khai Le Thieu ◽  
Håvard Jostein Haugen ◽  
Javier Sanz‐Esporrin ◽  
Mariano Sanz ◽  
Ståle Petter Lyngstadaas ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
In Vivo Study ◽  
Porous Block

scholarly journals In Vitro and In Vivo Study of a Novel Porcine Collagen Membrane for Guided Bone Regeneration

Materials ◽  
2016 ◽  
Vol 9 (11) ◽  
pp. 949 ◽  
Author(s):  
Eisner Salamanca ◽  
Chi-Yang Tsai ◽  
Yu-Hwa Pan ◽  
Yu-Te Lin ◽  
Haw-Ming Huang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Study ◽  
Collagen Membrane ◽  
Porcine Collagen

Bone regeneration in long-bone defects: tissue compartmentalisation? In vivo study on bone defects in sheep

Injury ◽  
2009 ◽  
Vol 40 ◽  
pp. S95-S102 ◽  
Author(s):  
Kaj Klaue ◽  
Ulf Knothe ◽  
Christoph Anton ◽  
Dominik H Pfluger ◽  
Martin Stoddart ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defects ◽  
In Vivo Study ◽  
Long Bone

scholarly journals Chitosan Nanoparticles of 5-Fluorouracil for Ophthalmic Delivery: Characterization, in-Vitro and in-Vivo Study

2011 ◽  
Vol 59 (2) ◽  
pp. 272-278 ◽  
Author(s):  
Ramesh Chand Nagarwal ◽  
Paras Nath Singh ◽  
Shri Kant ◽  
Pralay Maiti ◽  
Jayanta Kumar Pandit
Keyword(s):  
Chitosan Nanoparticles ◽  
In Vivo Study ◽  
Ophthalmic Delivery

Impact of Calcium Phosphate Particle Morphology on Osteoconduction: an In Vivo Study

2007 ◽  
Vol 361-363 ◽  
pp. 1237-1240 ◽  
Author(s):  
Christophe Drouet ◽  
Ronan Barré ◽  
Gérard Brunel ◽  
Gérard Dechambre ◽  
Edmond Benqué ◽  
...  
Keyword(s):  
Hydrothermal Synthesis ◽  
Chemical Composition ◽  
Calcium Phosphate ◽  
Bone Regeneration ◽  
Particle Morphology ◽  
In Vivo Study ◽  
Total Absence

Apatite/β−TCP particles exhibiting non-conventional urchin-like morphology were prepared by hydrothermal synthesis. Their implantation in the rat calvarium was followed during 60 days. A total absence of osteoconduction was observed despite a favorable chemical composition, stressing the fundamental role of particle morphology on bone regeneration. Results are discussed in relation with other literature data. Possible explanations include the disfavored accumulation of biological mediators due to the acicular shape of the particles and/or a limited accessibility for cells.

scholarly journals Biocompatibility and bone regeneration of PEO/Mg-Al LDH-coated pure Mg: an in vitro and in vivo study

2020 ◽  
Author(s):  
Jie Wang ◽  
Feng Peng ◽  
Xiaolin Wu ◽  
Donghui Wang ◽  
Ao Zheng ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
In Vivo Study
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