Effect of caffeic acid phenethyl ester (CAPE) on H2O2 induced oxidative and inflammatory responses in human middle ear epithelial cells

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Sunyoung Cho ◽  
...  
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Seok-Won Park ◽  
...  

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Kyou-nam Cho ◽  
Joo-heon Yoon

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Jae-Jun Song

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Kyoung-Seob Song ◽  
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Alfred F. Michael

Prostaglandins were found in the middle ear effusion and may play an important role in inflammation and bone resorption occurring in otitis media. With the use of an immunohistochemical technique, prostaglandin cyclooxygenase was localized in epithelial cells of human skin, endothelial cells of arterioles, mononuclear leukocytes and fibroblasts of human middle ear mucosa and granulation tissue, epithelial cells of chinchilla middle ear mucosa, and the external auditory canal skin.


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