scholarly journals Intravesical drug delivery approaches for improved therapy of urinary bladder diseases

Author(s):  
Luca Palugan ◽  
Matteo Cerea ◽  
Micol Cirilli ◽  
Saliha Moutaharrik ◽  
Alessandra Maroni ◽  
...  
2021 ◽  
pp. 104063872110040
Author(s):  
Emily Jones ◽  
John Alawneh ◽  
Mary Thompson ◽  
Rachel Allavena

Urinary bladder diseases are common in dogs and cats; however, there is little published work on urinary bladder disease in Australian pets. We identified pathology records of Australian dogs and cats with urinary bladder tissue submitted to the University of Queensland Veterinary Laboratory Service during 1994–2016 ( n = 320). We described the proportion of bladder diseases in dogs and cats, and applied the less-commonly used logistic regression procedure to quantify associations between signalment variables and disease diagnosis that were evident using descriptive statistics alone. After preliminary analysis, both species were combined because of similar results. Spayed/castrated animals were 74% less likely to be diagnosed with cystitis compared with intact animals. Animals 4–11 y old were also at lower risk of being diagnosed with cystitis compared with younger or older animals. Male animals were at increased risk of neoplasia compared to females, which contrasts with reports from North America and Europe. There was increased risk for developing neoplasia with progressive age, with up to 20 times higher odds in the > 11-y age group. Logistic regression modeling provided unique insight into proportionate morbidity of urinary bladder diseases in Australian dogs and cats.


2010 ◽  
pp. 199-199
Author(s):  
Suresh Bakle ◽  
Bipin Daga

2015 ◽  
Vol 8 (7) ◽  
pp. 819-822 ◽  
Author(s):  
Dinesh Dehmiwal ◽  
S.M. Behl ◽  
Prem Singh ◽  
Rishi Tayal ◽  
Madan Pal ◽  
...  

2015 ◽  
Author(s):  
Ilya Rafailov ◽  
Scott Palmer ◽  
Karina Litvinova ◽  
Victor Dremin ◽  
Andrey Dunaev ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Pradeep Tyagi ◽  
Mahendra P. Kashyap ◽  
Naoki Kawamorita ◽  
Tsuyoshi Yoshizawa ◽  
Michael Chancellor ◽  
...  

Purpose. The following review focuses on the recent advancements in intravesical drug delivery, which brings added benefit to the therapy of detrusor overactivity and interstitial cystitis/painful bladder syndrome (IC/PBS). Results. Intravesical route is a preferred route of administration for restricting the action of extremely potent drugs like DMSO for patients of interstitial cystitis/painful bladder syndrome (IC/PBS) and botulinum toxin for detrusor overactivity. Patients who are either refractory to oral treatment or need to mitigate the adverse effects encountered with conventional routes of administration also chose this route. Its usefulness in some cases can be limited by vehicle (carrier) toxicity or short duration of action. Efforts have been underway to overcome these limitations by developing liposome platform for intravesical delivery of biotechnological products including antisense oligonucleotides. Conclusions. Adoption of forward-thinking approaches can achieve advancements in drug delivery systems targeted to future improvement in pharmacotherapy of bladder diseases. Latest developments in the field of nanotechnology can bring this mode of therapy from second line of treatment for refractory cases to the forefront of disease management.


2015 ◽  
Vol 71 (9) ◽  
pp. 60-64 ◽  
Author(s):  
Christian Hopmann ◽  
Daniel Kaltbeitzel ◽  
Theresa Kauth ◽  
Barbara Dittrich ◽  
Joachim Grosse ◽  
...  

2018 ◽  
Vol 111 ◽  
pp. 83-90 ◽  
Author(s):  
Daulet B. Kaldybekov ◽  
Prasopchai Tonglairoum ◽  
Praneet Opanasopit ◽  
Vitaliy V. Khutoryanskiy

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