Stereotactic body radiotherapy for bilateral primary lung cancers: The Indiana University experience

2006 ◽  
Vol 66 (4) ◽  
pp. 1120-1124 ◽  
Author(s):  
Bedatri Sinha ◽  
Ronald C. McGarry
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Indiana University ◽  
Lung Cancers ◽  
University Experience

scholarly journals Surgical Treatment of Local Recurrence After Stereotactic Body Radiotherapy for Primary and Metastatic Lung Cancers

2010 ◽  
Vol 5 (12) ◽  
pp. 2003-2007 ◽  
Author(s):  
Shinya Neri ◽  
Yutaka Takahashi ◽  
Takuya Terashi ◽  
Hiroshi Hamakawa ◽  
Keisuke Tomii ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Local Recurrence ◽  
Stereotactic Body Radiotherapy ◽  
Lung Cancers ◽  
Metastatic Lung

Experimental evaluations of the accuracy of 3D and 4D planning in robotic tracking stereotactic body radiotherapy for lung cancers

2013 ◽  
Vol 40 (4) ◽  
pp. 041712 ◽  
Author(s):  
Mark K. H. Chan ◽  
Dora L. W. Kwong ◽  
Sherry C. Y. Ng ◽  
Anthony S. M. Tong ◽  
Eric K. W. Tam
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Lung Cancers ◽  
Robotic Tracking

scholarly journals Prognostic impact of average iodine density assessed by dual-energy spectral imaging for predicting lung tumor recurrence after stereotactic body radiotherapy

2016 ◽  
Vol 57 (4) ◽  
pp. 381-386 ◽  
Author(s):  
Masahiko Aoki ◽  
Katsumi Hirose ◽  
Mariko Sato ◽  
Hiroyoshi Akimoto ◽  
Hideo Kawaguchi ◽  
...  
Keyword(s):  
Local Control ◽  
Stereotactic Body Radiotherapy ◽  
Lung Tumor ◽  
Lung Metastases ◽  
Prognostic Significance ◽  
Lung Tumors ◽  
Dual Energy ◽  
Hypoxic Cell ◽  
Prognostic Impact ◽  
Lung Cancers

Abstract The purpose of this study was to investigate the prognostic significance of average iodine density as assessed by dual-energy computed tomography (DE-CT) for lung tumors treated with stereotactic body radiotherapy (SBRT). From March 2011 to August 2014, 93 medically inoperable patients with 74 primary lung cancers and 19 lung metastases underwent DE-CT prior to SBRT of a total dose of 45–60 Gy in 5–10 fractions. Of these 93 patients, nine patients had two lung tumors. Thus, 102 lung tumors were included in this study. DE-CT was performed for pretreatment evaluation. Regions of interest were set for the entire tumor, and average iodine density was obtained using a dedicated imaging software and evaluated with regard to local control. The median follow-up period was 23.4 months (range, 1.5–54.5 months). The median value of the average iodine density was 1.86 mg/cm 3 (range, 0.40–9.27 mg/cm 3 ). Two-year local control rates for the high and low average iodine density groups divided by the median value of the average iodine density were 96.9% and 75.7% ( P = 0.006), respectively. Tumors with lower average iodine density showed a worse prognosis, possibly reflecting a hypoxic cell population in the tumor. The average iodine density exhibited a significant impact on local control. Our preliminary results indicate that iodine density evaluated using dual-energy spectral CT may be a useful, noninvasive and quantitative assessment of radio-resistance caused by presumably hypoxic cell populations in tumors.

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