High-dose, Spot Scanning Based Proton Therapy For Paraspinal / Retroperitoneal Neoplasms and Small Bowel Tolerance: Dose Distribution Analysis in a Patient Cohort

Author(s):  
R.A. Schneider ◽  
V. Vitolo ◽  
F. Albertini ◽  
T. Koch ◽  
C. Ares ◽  
...  
2013 ◽  
Vol 189 (12) ◽  
pp. 1020-1025 ◽  
Author(s):  
R.A. Schneider ◽  
V. Vitolo ◽  
F. Albertini ◽  
T. Koch ◽  
C. Ares ◽  
...  

Author(s):  
V. V. Siksin

The use of “warm liquid” tetramethylsilane (TMS) in ionization chambers for measuring dose profiles in water phantoms to prepare the accelerator for a proton therapy session is relevant. One of the promising areas of radiation therapy is proton therapy. To increase the conformality of proton therapy, it is important to know exactly the dose distributions from the energy release of the proton beam in the water phantom before conducting a proton therapy session. A television-type detector (TTD), which measures the profiles of the Bragg peak by the depth of the beam in the water phantom, helps to increase the accuracy of the dose distribution knowledge. To accurately determine the profile of the Bragg peak by the beam width in the water phantom, an additional method is proposed that will allow TTD to quickly determine the profile by the width of the Bragg peak in on-line mode. This prefix to the TTD will improve the quality of summing up the therapeutic beam-thanks to accurate knowledge of the profile by width, and therefore the formed high-dose distribution field will correspond to the irradiated volume in the patient and will increase the conformality of irradiation. The additional prefix to the TTD is designed on an organosilicon “warm liquid” and represents a high-precision ionization chamber with coordinate sensitivity along the width of the water phantom. The fully developed technology for obtaining “warm liquid” TMS allows creating both microdosimeters for proton therapy and detectors for measuring “dose profiles” in water phantoms during accelerator calibration. The considered prefix to the TTD detector - the calibrator meter of the dose field (KIDP) - can also be used independently of the TTD and with great accuracy measure the dose profiles of the Bragg peak in the water phantom, both in depth and width. KIDP can also be used to measure the outputs of secondary “instantaneous” neutrons and gamma quanta emitted from the water phantom orthogonally to the direction of the proton beam.


2021 ◽  
Author(s):  
Konrad P. Nesteruk ◽  
Michele Togno ◽  
Martin Grossmann ◽  
Anthony J. Lomax ◽  
Damien C. Weber ◽  
...  

2021 ◽  
Vol 18 ◽  
pp. 11-18
Author(s):  
Lia Barbosa Valdetaro ◽  
Ellen Marie Høye ◽  
Peter Sandegaard Skyt ◽  
Jørgen Breede Baltzer Petersen ◽  
Peter Balling ◽  
...  

2021 ◽  
Vol 07 (02) ◽  
pp. 085-088
Author(s):  
Hanady Hegazy ◽  
Neamat Hegazy ◽  
Maher Soliman ◽  
Amr Elsaid

AbstractConcurrent chemoradiotherapy is considered the standard treatment for the locally advanced cancer cervix (LACC). Radiotherapy is commonly administered by a three-dimensional conformal radiotherapy (3DCRT) approach followed by brachytherapy (BT). High dose rate (HDR) BT is commonly administered; however, several drawbacks exist including invasive technique, pain, requirement of anesthesia, and operative risks. We assessed the dosimetric difference between the HDR BT and the volumetric modulated arc therapy (VMAT) boost in those patients. Ten patients were selected retrospectively with LACC and all received whole pelvis radiotherapy followed by BT boost of 7 Gy in three fractions. The computed tomography (CT) image was transferred to the Varian system for the VMAT plan while the one with the applicator was transferred to the Sagi planning system and the high-risk clinical target volume (HR-CTV), bladder, rectum, sigmoid, and small bowel were delineate with a margin of 5 mm were added to the CTV to create the planning target volume (PTV). The D90 for the PTV in VMAT boost was lower than received by the HR-CTV in the BT boost. Mean volume of the PTV was higher than that of the HR-CTV. The D2cc was higher in VMAT for bladder, sigmoid, and rectum while the D2cc for the small bowel in BT was higher compared with the VMAT. The VMAT is an option that exists for patients who refuse BT or cannot tolerate it, or in case of nonavailability of BT or a nonworking machine.


2020 ◽  
Vol 152 ◽  
pp. S848
Author(s):  
A. Köthe ◽  
P. Van Luijk ◽  
S. Safai ◽  
M. Kountouri ◽  
D.C. Weber ◽  
...  

2016 ◽  
Vol 17 (5) ◽  
pp. 366-376 ◽  
Author(s):  
Xin Wang ◽  
Falk Poenisch ◽  
Narayan Sahoo ◽  
Ronald X. Zhu ◽  
MingFwu Lii ◽  
...  

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