scholarly journals Long-Term Results of a Prospective Pilot Safety and Feasibility Study of Adjuvant Concurrent Capecitabine and External Beam Irradiation Demonstrates Tolerability and Efficacy in High-Risk Locally Advanced Breast Cancer

2017 ◽  
Vol 99 (2) ◽  
pp. S215 ◽  
Author(s):  
D.T. Vo ◽  
A.S. Rahimi ◽  
J. O'shaughnessy ◽  
A.E. Spangler ◽  
J. Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Advanced Breast Cancer ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Long Term Results ◽  
External Beam ◽  
Beam Irradiation ◽  
External Beam Irradiation

Multimodality Treatment of Locally-Advanced Breast Cancer Using 6.3 MeV Fast Neutrons and Quality of Life in Patients in Long-Term Follow-Up

2015 ◽  
Vol 1084 ◽  
pp. 406-408
Author(s):  
Zhanna Startseva ◽  
Ludmila Musabaeva ◽  
Valerij Lisin
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Multimodality Treatment ◽  
Advanced Breast ◽  
Long Term Results ◽  
Fast Neutrons ◽  
Combined Modality Treatment

The purpose of the study is to present the 10-year results of the combined modality treatment with the use of neutron-photon therapy for patients with T2-4N0-2M0 locally advanced breast cancer (LABC). The study involved 246 LABC patients (T2-4N0-2M0). Analysis of long-term results of multimodality treatment of patients with primary LABC has shown that preoperative neutron therapy is the most effective in the presence of multicentric tumors, radioresistance to neoadjuvant chemotherapy and other adverse prognostic factors.

Long-term Survival after Cerebellar Metastasis Resection from Her2 3+ Locally Advanced Breast Cancer

2015 ◽  
Vol 11 (1) ◽  
pp. 36
Author(s):  
Zorica I Tomasevic ◽  
Zoran M Tomasevic ◽  
Zeljko Kovac ◽  
Zorka Milovanovic ◽  
Dana Grujicic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Advanced Breast ◽  
Disease Course ◽  
Term Survival ◽  
Cerebellar Metastasis ◽  
Distant Metastatic Site

We present a patient who first developed a distant metastatic site in the cerebellum during treatment for Her2 3+ locally advanced breast cancer (LABC). LABC was in complete remission at that time and isolated cerebellar metastasis was resected. The patient is still alive more than 135 months after LABC diagnosis, and more than 99 months after neurosurgery, and is still receiving trastuzumab without further progression or any toxicity. To the best of our knowledge, this is first report of such exceptional disease course for a patient with a predicted grave prognosis according to all prognostic parameters.

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