scholarly journals Complete wedge resection for duodenal gastrointestinal stromal tumour: A case series of three patients

2022 ◽  
Vol 90 ◽  
pp. 106674
Author(s):  
Tomoaki Ito ◽  
Tomoyuki Kushida ◽  
Mutsumi Sakurada ◽  
Kenichiro Tanaka ◽  
Koichi Sato ◽  
...  
Keyword(s):  
Wedge Resection ◽  
Case Series ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour

scholarly journals Relative Hypocalcaemia and Muscle Cramps in Patients Receiving Imatinib for Gastrointestinal Stromal Tumour

Sarcoma ◽  
2006 ◽  
Vol 2006 ◽  
pp. 1-3 ◽  
Author(s):  
Jamal M. Zekri ◽  
Martin H. Robinson ◽  
Penella J. Woll
Keyword(s):  
Serum Calcium ◽  
Medical Records ◽  
Case Series ◽  
Gastrointestinal Stromal Tumour ◽  
Index Patient ◽  
Stromal Tumour ◽  
Imatinib Treatment ◽  
Muscle Cramps ◽  
Sustained Reduction ◽  
Lower Limit Of Normal

Purpose. Imatinib treatment causes muscle cramps in up to 40% of patients, but their pathogenesis is unknown. We present a case series illustrating an association between imatinib, relative hypocalcaemia, and the development of cramps.Patients. The index patient developed muscle spasms and cramps after receiving imatinib for gastrointestinal stromal tumour (GIST) for 5 months. The adjusted serum calcium had dropped to the lower limit of normal. The low serum calcium and muscle cramps improved on stopping imatinib and recurred on rechallenge. We reviewed the medical records of 16 further patients.Results. Two patients reported muscle cramps (12%). There was a rapid and sustained reduction in adjusted serum calcium in the first 6 months from 2.45 ± 0.11 mmol/L (mean ± SD) to 2.30 ± 0.08 mmol/L (p=0.025).Conclusion. Imatinib treatment of GIST is associated with reduction in serum calcium which may explain the development of neuromuscular symptoms. In patients receiving imatinib, serum electrolytes should be monitored and muscle cramps treated by correction of serum calcium, or an empirical trial of quinine sulphate.

scholarly journals Acute abdomen in children due to different presentations of complicated Meckel’s diverticulum: a case series

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Hisham A. Almetaher ◽  
Mohammed Awad Mansour
Keyword(s):  
Congenital Abnormality ◽  
Wedge Resection ◽  
Meckel’S Diverticulum ◽  
Case Series ◽  
Postoperative Outcome ◽  
Meckel's Diverticulum ◽  
Gastrointestinal Disorders ◽  
Clinical Presentations ◽  
Life Threatening ◽  
Small Base

Abstract Background Meckel’s diverticulum (MD) is the commonest congenital abnormality of the gastrointestinal tract that occurs in 2% of general population. It remains asymptomatic, but it may lead to life-threatening complications. These complications may be misdiagnosed with other gastrointestinal disorders like acute appendicitis, making its diagnosis challenging among pediatricians and pediatric surgeons. In this study, we reported five cases with different presentations of complicated MD in children. Results Five patients with different presentations of MD were reported during the period from January 2016 to January 2020. Patients’ demographics, clinical presentations, investigations, operative data, and postoperative outcome were recorded and analyzed. Conclusions The present study highlights different presentations of MD. Surgical interference is the main key of treatment of symptomatic MD either by wedge resection of a small base diverticulum or by resection anastomosis of the small intestine in wide base and inflamed diverticulum.

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