EquineReview

Introduction: This month's Equine Review presents papers on a large prospective European study of the efficacy and safety of the glucocorticoid prodrug ciclesonide, changes in the faecal microbiota of horses hospitalised for colic and the comparison of chlorhexidine and alcohol-based antisepsis of the equine distal limb.

The COVID-19 pandemic and changes in the level of contact between older parents and their non-coresident children: A European study

Objective: The present study aims to investigate changes in the frequency of parent-child contact among Europeans aged 65 years and over within the context of the COVID-19 pandemic, while recognizing heterogeneity within the group of older adults. Background: Physical distancing measures have been implemented worldwide to curb the spread of the COVID-19 pandemic. Although this policy has proven to be effective in flattening the curve, it undoubtedly posed a serious challenge to intergenerational relations. Experts hinted that physical distancing measures may have reduced older adults’ level of contact with their non-coresident children. However, empirical evidence is lacking. Method: Data from the SHARE COVID-19 questionnaire and previous SHARE waves for 26,077 individuals from 26 European countries and Israel were used and analyzed using multilevel multinomial logistic regression analysis. Results: The analysis revealed that older adults’ level of intergenerational contact remained stable or even increased – rather than decreased – during the COVID-19 pandemic. Despite the overall positive outcome, some subgroups (i.e., older men, residents of nursing homes, less educated older adults and older adults living in countries with less stringent COVID-19 measures) were more likely to report reduced intergenerational contact. Conclusion: Although variation was observed among older adults, the pandemic generally did not pose a threat to their level of intergenerational contact with non-coresident children.

Brazilian Validation of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) Computerised Adaptive Tests (CAT) Core

Background: This study aimed to validate the Brazilian version of EORTC CAT Core and compare the Brazilian results with those from the original European EORTC CAT Core validation study. Methods: After validated translation, 168 cancer patients from Brazil receiving radiation therapy with or without chemotherapy was assessed. Translated EORTC CAT Core and all QLQ-C30 items were administered to patients using CHES (Computer-Based Health Evaluation System) before (T0) and after (T1) treatment initiation. The association between QLQ-C30 and CAT scores and ceiling/floor effects were estimated. Based on estimates of relative validity (cross-sectional, known-group differences and changes over time), relative sample-size requirements for CAT compared to QLQ-C30 were estimated. Results: Correlation coefficients between CAT and QLQ-C30 domains ranged from 0.63 to 0.93; except for dyspnoea, all coefficients were >0.82 (corresponding figures were 0.81–0.93 in the European study). On average across domains, floor/ceiling was reduced by 10% using CAT (9% in the European study) corresponding to a relative reduction of 32% (37% in the European study). Analyses of known-group validity and responsiveness indicated that, on average across domains, the sample-size requirements may be reduced by 17% using CAT rather than QLQ-C30, without loss of power (28% in the European study). The Brazilian sample had less symptom/quality of life impairment than the European sample, which likely explains the lower sample-size reduction using CAT when comparing with the European sample. Conclusions: The results in the Brazilian cohort were generally similar to those from the European sample and confirm the validity and usefulness of the EORTC CAT Core.