scholarly journals Peer review report 1 on "Prospective validation of a preoperative risk score model based on pancreatic texture to predict postoperative pancreatic fistula after pancreaticoduodenectomy."

2017 ◽  
Vol 37 ◽  
pp. 589
Author(s):  
Frederik Berrevoet

2017 ◽  
Vol 48 ◽  
pp. 189-194 ◽  
Author(s):  
Riccardo Casadei ◽  
Claudio Ricci ◽  
Giovanni Taffurelli ◽  
Carlo Alberto Pacilio ◽  
Mariacristina Di Marco ◽  
...  


Pancreatology ◽  
2016 ◽  
Vol 16 (3) ◽  
pp. S76-S77
Author(s):  
Giovanni Taffurelli ◽  
Claudio Ricci ◽  
Donatella Santini ◽  
Anna Guariniello ◽  
Carlo Alberto Pacilio ◽  
...  


2021 ◽  
Vol 105 (1-3) ◽  
pp. 559-563
Author(s):  
Seungmin Lee ◽  
Kwang Yeol Paik

Background The aim of this study is to examine whether pancreaticogastrostomy (PG) or pancreaticojejunostomy (PJ) is the better reconstructive method to reduce postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) according to the fistula risk. Methods An institutional database was reviewed for patients undergoing PD between January 2008 and August 2019. A total of 159 patients were stratified into 4 groups according to the Clinical Risk Score-Pancreatic Fistula. POPF according to 4 risk groups was compared between PJ and PG. Results Of the 159 patients, 82 underwent PG (51.6%) and 77 underwent PJ (48.4%) reconstruction. POPF rate was 17.1% (n = 14) in the PG group and 12.9% (n = 10) in the PJ group (P = 0.51). POPF rates were not different in intermediate, low, and negligible risks between 2 reconstructive methods. In the high-risk group (n = 47), there were 4 POPFs (22.2%) in PJ group and 9 (31.0%) in the PG group, respectively (P = 0.74). Conclusion In PD, there was no superior method of reconstruction with regard to POPF, even in high-risk glands.





BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Ying Chen ◽  
Bo Zhao ◽  
Xiaohu Wang

Abstract Background Osteosarcoma is a rare malignant bone tumor in adolescents and children. Poor prognosis has always been a difficult problem for patients with osteosarcoma. Recent studies have shown that tumor infiltrating immune cells (TIICs) are associated with the clinical outcome of osteosarcoma patients. The aim of our research was to construct a risk score model based on TIICs to predict the prognosis of patients with osteosarcoma. Methods CIBERSORTX algorithm was used to calculate the proportion of 22 TIIC types in osteosarcoma samples. Kaplan-Meier curves were drawn to investigate the prognostic value of 22 TIIC types. Forward stepwise approach was used to screen a minimal set of immune cell types. Multivariate Cox PHR analysis was performed to construct an immune risk score model. Results Osteosarcoma samples with CIBERSORTX output p value less than 0.05 were selected for research. Kaplan-Meier curves indicated that naive B cells (p = 0.047) and Monocytes (p = 0.03) in osteosarcoma are associated with poor prognosis. An immune risk score model was constructed base on eight immune cell types, and the ROC curve showed that the immune risk score model is reliable in predicting the prognosis of patients with osteosarcoma (AUC = 0.724). Besides, a nomogram model base on eight immune cell types was constructed to predict the survival rate of patients with osteosarcoma. Conclusions TIICs are closely related to the prognosis of osteosarcoma. The immune risk score model based on TIICs is reliable in predicting the prognosis of osteosarcoma.



2016 ◽  
Vol 64 (3) ◽  
pp. 832
Author(s):  
Albeir Mousa ◽  
Mike Broce ◽  
Michael Yacoub ◽  
Andrew Sticco ◽  
Mina Baskharoun ◽  
...  


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