WITHDRAWN: Commentary on: A systematic review and meta-analysis of risk factors for unruptured intracranial aneurysm growth

Background: Headaches are a major cause of disability and healthcare cost worldwide. When investigating headaches etiology, incidental unruptured intracranial aneurysms are often considered unrelated. We conducted a systematic review and meta-analysis to assess headaches outcomes (severity) after treatment of unruptured intracranial aneurysm. Methods: MEDLINE and EMBASE were systematically reviewed. Results: The data from eligible studies (n=7) was extracted and analyzed. 309 nonduplicated patients provided patient-level data for analysis. All studies used the 10-point numeric rating scale (NRS). 88% of patients were treated with endovascular technique. Overall, the observed effect estimate under a random effects model was found to be a standard mean difference in pre- and post-intervention headache severity of -0.448 (95% CI: -0.566 to -0.329). No significant heterogeneity was noted. No significant publication bias was demonstrated. Conclusions: This is the first and largest systematic review assessing postoperative headache outcomes after treatment of unruptured intracranial aneurysm. A significant reduction in headache intensity after treatment is observed in the current published literature. This study highlights an interesting clinical phenomenon that still warrants scientific effort before it can influence clinical practice. We encourage future study to stratify headache outcomes by aneurysm size, location and treatment modality.

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Headache Outcomes After Treatment of Unruptured Intracranial Aneurysm

Stroke ◽

10.1161/strokeaha.119.026864 ◽

2019 ◽

Vol 50 (12) ◽

pp. 3628-3631 ◽

Cited By ~ 1

Author(s):

Charlotte Dandurand ◽

Harman S. Parhar ◽

Faysal Naji ◽

Swetha Prakash ◽

Gary Redekop ◽

...

Keyword(s):

Systematic Review ◽

Intracranial Aneurysm ◽

Meta Analysis ◽

Significant Heterogeneity ◽

Post Intervention ◽

Unruptured Intracranial Aneurysm ◽

Headache Severity ◽

Standard Mean Difference ◽

Unruptured Intracranial Aneurysms ◽

Postoperative Headache

Background and Purpose— While unruptured intracranial aneurysms may be discovered incidentally in the workup of chronic headache, it remains unclear whether their treatment ultimately impacts headache severity. We aim to conduct a systematic review and meta-analysis assessing headache severity after treatment of unruptured intracranial aneurysm. Methods— MEDLINE and EMBASE were systematically reviewed. Results— Data from 7 studies met inclusion criteria (309 nonduplicated patients). The standard mean difference in pre- and post-intervention headache severity was estimated at −0.448 (95% CI, −0.566 to −0.329) under a random effects model. No significant heterogeneity was noted nor was any significant publication bias demonstrated. Conclusions— This is the first systematic review assessing postoperative headache severity following treatment of unruptured intracranial aneurysm. While a significant reduction in headache severity was observed, further investigation into this phenomenon is recommended before it influences clinical practice. Future study should stratify headache outcomes by aneurysm size, location, and treatment modality.

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Factors Affecting Quality of Life in Patients with Unruptured Intracranial Aneurysm: A Systematic Review

Journal of Korean Academy of Fundamentals of Nursing ◽

10.7739/jkafn.2020.27.1.81 ◽

2020 ◽

Vol 27 (1) ◽

pp. 81-94

Author(s):

Hayoung Park ◽

Jinyoung Choi ◽

Sang Hui Chu

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Intracranial Aneurysm ◽

Short Form ◽

Meta Analysis ◽

Well Being ◽

Unruptured Intracranial Aneurysm ◽

Related Factors ◽

Factors Affecting

Purpose: The purpose of this study was to comprehensively explore factors affecting quality of life in patients with unruptured intracranial aneurysm (UIA).Methods: This study was conducted base on the National Evidence-based Healthcare Collaborating Agency (NECA) and Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). To search studies related to quality of life in patients with UIA. KoreaMed, Kmbase, Kiss, Pubmed, EMBASE, Cochrane Central and CINAHL were used. Key words were 'unruptured intracranial aneurysm', 'quality of life' and 'well-being'. A total of 136 studies were identified. After confirming duplication and abstracts, 15 studies were selected for analysis.Results: As a result, factors affecting the quality of life in patients with UIA were categorized into individual factors, disease related factors, symptom related factors, and functional related factors. The Short form-36 was one of the most frequently used measurements.Conclusion: To improve the quality of life of patients with UIA, researchers need to explore the multiple factors affecting quality of life in patients with UIA, and consider application of tools that can reflect the disease specific quality of life in patients with UIA.

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