The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations

Immunity ◽

10.1016/j.immuni.2018.09.007 ◽

2018 ◽

Vol 49 (5) ◽

pp. 829-841.e6 ◽

Author(s):

Kristine N. Brazin ◽

Robert J. Mallis ◽

Andras Boeszoermenyi ◽

Yinnian Feng ◽

Akihiro Yoshizawa ◽

...

Keyword(s):

T Cell ◽

Transmembrane Domain ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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Lysine 271 in the transmembrane domain of the T-cell antigen receptor beta chain is necessary for its assembly with the CD3 complex but not for alpha/beta dimerization.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)39712-1 ◽

1990 ◽

Vol 265 (7) ◽

pp. 4131-4135

Author(s):

A Alcover ◽

R A Mariuzza ◽

M Ermonval ◽

O Acuto

Keyword(s):

T Cell ◽

Transmembrane Domain ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

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Faculty Opinions recommendation of Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007978.115962 ◽

2002 ◽

Author(s):

Roger Williams

Keyword(s):

T Cell ◽

Antigen Receptor ◽

Mutant Mice ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling

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Faculty Opinions recommendation of Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007978.109814 ◽

2002 ◽

Author(s):

Marie Kosco-Vilbois

Keyword(s):

T Cell ◽

Antigen Receptor ◽

Mutant Mice ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling

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Faculty Opinions recommendation of Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022661.260651 ◽

2004 ◽

Author(s):

Sergio Grinstein

Keyword(s):

T Cell ◽

Actin Cytoskeleton ◽

Molecular Interactions ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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Faculty Opinions recommendation of Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108753.564866 ◽

2008 ◽

Author(s):

Scott Gray-Owen

Keyword(s):

T Cell ◽

Negative Selection ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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Faculty Opinions recommendation of Vitamin D controls T cell antigen receptor signaling and activation of human T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2517956.2321060 ◽

2010 ◽

Author(s):

Gerald Spangrude

Keyword(s):

Vitamin D ◽

T Cells ◽

T Cell ◽

Antigen Receptor ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling ◽

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Faculty Opinions recommendation of Vitamin D controls T cell antigen receptor signaling and activation of human T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2517956.2163054 ◽

2010 ◽

Author(s):

Luciano Adorini

Keyword(s):

Vitamin D ◽

T Cells ◽

T Cell ◽

Antigen Receptor ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling ◽

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Faculty Opinions recommendation of The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5725965.5708063 ◽

2010 ◽

Author(s):

Iannis Aifantis

Keyword(s):

T Cell ◽

Antigen Receptor ◽

Structural Basis ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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Faculty Opinions recommendation of Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718359865.793494212 ◽

2014 ◽

Author(s):

Florian Kern

Keyword(s):

T Cell ◽

Protein C ◽

Antigen Receptor ◽

Γδ T Cell ◽

Endothelial Protein C Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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Faculty Opinions recommendation of T cell antigen receptor signaling and immunological synapse stability require myosin IIA.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.722723157.793515721 ◽

2016 ◽

Author(s):

Miguel Vicente-Manzanares

Keyword(s):

T Cell ◽

Immunological Synapse ◽

Antigen Receptor ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling ◽

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