Retroperitoneal schwannoma associated with neuropathic pain and electromyographic and nerve conduction abnormalities: A case report

The cognitive–evaluative (C–E) dimension of pain is commonly observed in patients with a relatively long duration of pain. However, little is known about the effects of pain relapse on the C–E dimension of pain. Moreover, the improvement process of the C–E dimension of pain following treatment is unknown. The objective of this case report was to (a) demonstrate that the C–E dimension was affected in the acute phase of neuropathic pain in cases of pain relapse, and (b) demonstrate the improvement process of the C–E dimension of pain. A woman was diagnosed with low back pain (LBP) and sciatica. The patient had previously experienced symptoms of LBP and sciatica; thus, this episode was a case of pain relapse. At the beginning of rehabilitation, the C–E dimension of pain was present in addition to the sensory–discriminative (S–D) dimension of pain. It was observed that improvement of the C–E dimension of pain was delayed in comparison with that of the S–D dimension of pain. The C–E dimension of pain was observed with pain relapse even though it was in the acute phase of pain. This case provides a novel insight into the C–E dimension of pain. Moreover, the delay in improving the C–E dimension of pain indicates a difference in the improvement process for each pain dimension.

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Neuropathic pain post-COVID-19: a case report

BMJ Case Reports ◽

10.1136/bcr-2021-243459 ◽

2021 ◽

Vol 14 (7) ◽

pp. e243459

Author(s):

Matthew McWilliam ◽

Michael Samuel ◽

Fadi Hasan Alkufri

Keyword(s):

Neuropathic Pain ◽

Case Report ◽

Hospital Admission ◽

Skin Biopsy ◽

Neurological Examination ◽

Autonomic Failure ◽

Whole Body ◽

Shortness Of Breath ◽

Burning Pain ◽

Electrophysiological Tests

A 61-year-old man with no significant medical history developed fever, headache and mild shortness of breath. He tested positive for SARS-CoV-2 and self-isolated at home, not requiring hospital admission. One week after testing positive, he developed acute severe burning pain affecting his whole body, subsequently localised distally in the limbs. There was no ataxia or autonomic failure. Neurological examination was unremarkable. Electrophysiological tests were unremarkable. Skin biopsy, lumbar puncture, enhanced MRI of the brachial plexus and MRI of the neuroaxis were normal. His pain was inadequately controlled with pregabalin but improved while on a weaning regimen of steroids. This case highlights the variety of possible symptoms associated with SARS-CoV-2 infection.

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Acupuncture in diabetic peripheral neuropathy—protocol for the randomized, multicenter ACUDPN trial

Trials ◽

10.1186/s13063-021-05110-1 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

J. Dietzel ◽

S. Hörder ◽

I. V. Habermann ◽

G. Meyer-Hamme ◽

K. Hahn ◽

...

Keyword(s):

Neuropathic Pain ◽

Peripheral Neuropathy ◽

Nerve Conduction ◽

Diabetic Peripheral Neuropathy ◽

Clinical Symptoms ◽

Multicenter Trial ◽

Routine Care ◽

Open Label ◽

Diabetes Type Ii ◽

Parallel Group

Abstract Background Acupuncture is used to treat patients with diabetic peripheral neuropathy; however, the evidence is unclear. We present the design and methodology of the ACUDPN (ACUpuncture in Diabetic Peripheral Neuropathy) trial, which investigates the effectiveness of acupuncture for the treatment of diabetic peripheral neuropathy (DPN) symptoms. The aim of this study is to investigate whether acupuncture is effective for the treatment of DPN symptoms. Methods This study is a two-armed, randomized, controlled, parallel group, open-label, confirmatory, multicenter trial (8-week intervention period plus 16 weeks of follow-up). Physicians in outpatient units in Germany who specialize in acupuncture treatment will treat 110 diabetes type II patients with clinical symptoms of peripheral neuropathy in the feet and legs with signs of neuropathy according to nerve conduction testing. The patients will be randomized in a 1:1 ratio to one of the following two groups: (a) semi-standardized acupuncture plus routine care or (b) routine care alone. Acupuncture will consist of 12 treatments per patient over 8 weeks. The primary outcome will be the overall DPN-related complaints in the extremities after 8 weeks as measured by the Visual Analog Scale (VAS). Further outcome measures will include DPN-related pain, the Neuropathic Pain Symptom Inventory (NPSI), Diabetic Peripheral Neuropathic Pain Impact (DPNPI) scores, and nerve conduction parameters of the sural nerve at weeks 8, 16, and 24. Discussion The results of this trial will be available in 2021 and will help clarify whether acupuncture can be considered effective for the treatment of DPN with regard to the subdimensions of the neuropathic clinical picture. Trial registration ClinicalTrials.gov NCT03755960. Registered on 11 August 2018.

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Regional migratory osteoporosis: case report of a patient with neuropathic pain

Rheumatology International ◽

10.1007/s00296-009-1256-1 ◽

2009 ◽

Vol 31 (10) ◽

pp. 1375-1381 ◽

Cited By ~ 2

Author(s):

Esin Kartal ◽

Ebru Sahin ◽

Banu Dilek ◽

Meltem Baydar ◽

Metin Manisali ◽

...

Keyword(s):

Neuropathic Pain ◽

Case Report ◽

Regional Migratory Osteoporosis

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Poster 261: Electromyography/Nerve Conduction Studies and Musculoskeletal Ultrasound in a Patient with Missing Thumbs in Holt Oram Syndrome: A Case Report

PM&R ◽

10.1016/j.pmrj.2017.08.201 ◽

2017 ◽

Vol 9 ◽

pp. S215-S215

Author(s):

Kelly N. Smith ◽

Amy T. Cao ◽

Faye Chiou Tan

Keyword(s):

Case Report ◽

Nerve Conduction ◽

Nerve Conduction Studies ◽

Musculoskeletal Ultrasound

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Two siblings with nerve conduction abnormalities indicating an acquired type of demyelinating neuropathy

Muscle & Nerve ◽

10.1002/(sici)1097-4598(199705)20:5<608::aid-mus11>3.0.co;2-s ◽

1997 ◽

Vol 20 (5) ◽

pp. 608-610

Author(s):

Akira Inaba ◽

Takanori Yokota ◽

Toshiaki Shiojiri ◽

Masahito Yamada

Keyword(s):

Nerve Conduction ◽

Demyelinating Neuropathy ◽

Conduction Abnormalities

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A Case Report on Post COVID -19 Vaccine Associated Guillain–Barré Syndrome

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i59b34403 ◽

2021 ◽

pp. 454-458

Author(s):

S. Hemalatha ◽

M. Karishma ◽

J. Bera ◽

S. Blessy ◽

J. Thirumaran ◽

...

Keyword(s):

Case Report ◽

Nerve Conduction ◽

Muscle Power ◽

Ventilatory Support ◽

Infectious Agent ◽

Guillain Barre Syndrome ◽

Autonomic Nerves ◽

Intravenous Immunoglobulin Therapy ◽

Guillain Barré Syndrome ◽

Guillain Barré

Guillain–Barré syndrome (GBS) is an autoimmune demyelinating illness in which a patient’s immune system attacks and cause deterioration of peripheral nervous system leading to progressive paralysis and polyneuropathy. The exact cause of the GBS is unclear but the main mechanism of behindis the demyelination of nerves especially the motor, sensory, and autonomic nerves which can be triggered by any immunologic or infectious agent. The infectious agent elicits the humoral and cellular mediated immune response due to their molecular mimicry in which the antibodies created against the infection matches with the proteins on the nerve. The characteristic features of Guillain–Barré syndrome are ascending flaccid paralysis, paresthesia, impairment of muscle reflexes, respiratory failureetc. The GBS is diagnosed via nerve conduction studies, lumbar puncture (Cerebrospinal fluid analysis), electromyography, Brighton criteria. Treatments like intravenous immunoglobulin therapy, plasma exchange can ease the symptoms and reduce the duration of the illness. This case report focusing on a 43-year-old female patient admitted seeking ventilatory support for respiratory distress caused by Guillain–Barré Syndrome in a tertiary hospital. Patient had developed limb weakness with ascending paralysis along with facial weakness within a couple of weeks after receiving the COVID -19 vaccination (COVISHIELD)one month back. Patient underwent nerve conduction study and routine monitoring of vital parameters. After conservative management with physiotherapy, ventilation, intravenous immunoglobulins and prophylaxis for pain and DVT patient gradually started improving the muscle power and was discharged to continue the rehabilitation care at home.

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