Preparation, structural analysis, antioxidant and digestive enzymes inhibitory activities of polysaccharides from Thymus quinquecostatus Celak. leaves

2022 ◽  
Vol 175 ◽  
pp. 114288
Author(s):  
Xiao Li ◽  
Xiuhuan Wang ◽  
Ying Dong ◽  
Ruolan Song ◽  
Jing Wei ◽  
...  
Keyword(s):  
Structural Analysis ◽  
Digestive Enzymes ◽  
Inhibitory Activities

Inhibitory activities of Rubi Fructus on digestive enzymes

2010 ◽  
Vol 19 (5) ◽  
pp. 1165-1170 ◽  
Author(s):  
Jung Sung Kim ◽  
Woo Jin Jeon ◽  
Hyun Ju You ◽  
Myung Soo Park ◽  
Geun Eog Ji
Keyword(s):  
Digestive Enzymes ◽  
Inhibitory Activities

scholarly journals Antioxidative and digestive enzymes inhibitory activities of 27 edible plants

2021 ◽  
Author(s):  
Ying LI ◽  
Dan YANG ◽  
Bo CHEN ◽  
Hai-Yan CAO ◽  
Qing-Feng ZHANG
Keyword(s):  
Digestive Enzymes ◽  
Edible Plants ◽  
Inhibitory Activities

Inhibitory activities ofUlva lactucapolysaccharides on digestive enzymes related to diabetes and obesity

2013 ◽  
Vol 119 (2) ◽  
pp. 81-87 ◽  
Author(s):  
Sahla BelHadj ◽  
Olfa Hentati ◽  
Abdelfattah Elfeki ◽  
Khaled Hamden
Keyword(s):  
Digestive Enzymes ◽  
Inhibitory Activities ◽  
Diabetes And Obesity

scholarly journals In VitroScreening of Medicinal Plants Used in Mexico as Antidiabetics with Glucosidase and Lipase Inhibitory Activities

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Guillermo Ramírez ◽  
Miguel Zavala ◽  
Julia Pérez ◽  
Alejandro Zamilpa
Keyword(s):  
Medicinal Plants ◽  
Dose Response ◽  
Lipase Activity ◽  
Digestive Enzymes ◽  
Inhibitory Effect ◽  
Active Species ◽  
Significant Inhibition ◽  
Response Curves ◽  
Inhibitory Activities ◽  
Positive Controls

This work shows the inhibitory effect on glucosidase and lipase enzymes of 23 medicinal plants described as traditional treatments for diabetes in several Mexican sources. Hydroalcoholic extracts of selected plants were evaluated at 1 mg/mL for glucosidase and 0.25 mg/mL for lipase inhibitory activities, respectively.Camellia sinensis, acarbose, and orlistat were used as positive controls. Dose-response curves were done with the most active species. Sixty percent of all tested extracts inhibited more than 25% ofα-glucosidase activity.C. sinensisdisplayed an inhibition of 85% (IC50 = 299 μg/mL), whileLudwigia octovalvisandIostephane heterophyllashowed the highest inhibition (82.7 %, IC50 = 202 μg/mL and 60.6%, CI50 = 509 μg/mL, resp.). With respect to lipase activity,L. octovalvisandTecoma stanswere the most inhibiting treatments (31.4%, IC50 = 288 μg/mL; 27.2%, IC50 = 320 μg/mL), whileC. sinensisdisplayed 45% inhibition (IC50 = 310 μg/mL). These results indicate that a high proportion of plants used in Mexico as treatment for diabetes displays significant inhibition of these digestive enzymes.

scholarly journals Acylated Aminooligosaccharides from the Yellow Sea Streptomyces sp. HO1518 as Both α-Glucosidase and Lipase Inhibitors

Marine Drugs ◽  
2020 ◽  
Vol 18 (11) ◽  
pp. 576
Author(s):  
Jian-Lin Xu ◽  
Hai-Li Liu ◽  
Zhi-Feng Liu ◽  
Yu-Hong Ren ◽  
Yong Wang
Keyword(s):  
Pancreatic Lipase ◽  
Future Development ◽  
Digestive Enzymes ◽  
Spectroscopic Analysis ◽  
The Yellow Sea ◽  
Chemical Transformations ◽  
Inhibitory Effects ◽  
Streptomyces Sp ◽  
Inhibitory Activities

Three new acylated aminooligosaccharide (1–3), along with five known congeners (4–8), were isolated from the marine-derived Streptomyces sp. HO1518. Their structures were fully elucidated by extensive spectroscopic analysis, mainly based on 1D-selective and 2D TOCSY, HSQC-TOCSY, and HRESIMS spectrometry measurements, and by chemical transformations. All of the compounds were evaluated for their α-glucosidase and pancreatic lipase inhibitory activities. Among the isolates, D6-O-isobutyryl-acarviostatin II03 (3) and D6-O-acetyl-acarviostatin II03 (8), sharing acarviostatin II03-type structure, showed the most potent α-glucosidase and lipase inhibitory effects, far stronger than the antidiabetic acarbose towards α-glucosidase and almost equal to the anti-obesity orlistat towards lipase in vitro. This is the first report on inhibitory activities against the two major digestive enzymes for acylated aminooligosaccharides. The results from our investigation highlight the potential of acylated aminooligosaccharides for the future development of multi-target anti-diabetic drug.

Parmotrema tinctorumexhibits antioxidant, antiglycation and inhibitory activities against aldose reductase and carbohydrate digestive enzymes: anin vitrostudy

2014 ◽  
Vol 28 (18) ◽  
pp. 1480-1484 ◽  
Author(s):  
P. Salin Raj ◽  
A. Prathapan ◽  
Jomon Sebastian ◽  
Antu K. Antony ◽  
Mariam Philip Riya ◽  
...  
Keyword(s):  
Aldose Reductase ◽  
Digestive Enzymes ◽  
Inhibitory Activities

Composition and inhibitory activities towards digestive enzymes of polyphenolic-rich fractions of Davidson's plum and quandong

LWT ◽  
2014 ◽  
Vol 57 (1) ◽  
pp. 366-375 ◽  
Author(s):  
Karunrat Sakulnarmrat ◽  
George Srzednicki ◽  
Izabela Konczak
Keyword(s):  
Digestive Enzymes ◽  
Inhibitory Activities
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