Cutaneous polyarteritis nodosa associated with Crohn’s disease, with improvement on low-dose dapsone

2018 ◽  
Vol 79 (3) ◽  
pp. AB95
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Polyarteritis Nodosa ◽  
Low Dose ◽  
Cutaneous Polyarteritis Nodosa

Cutaneous polyarteritis nodosa in a patient with Crohn’s disease

2008 ◽  
Vol 18 (6) ◽  
pp. 639-642 ◽  
Author(s):  
Atsushi Komatsuda ◽  
Koji Kinoshita ◽  
Masaru Togashi ◽  
Nobuki Maki ◽  
Rie Masai ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Polyarteritis Nodosa ◽  
Cutaneous Polyarteritis Nodosa

CUTANEOUS POLYARTERITIS NODOSA ASSOCIATED WITH CROHN'S DISEASE

The Lancet ◽  
1970 ◽  
Vol 295 (7648) ◽  
pp. 648-650 ◽  
Author(s):  
N.H. Dyer ◽  
J.L. Verbov ◽  
A.M. Dawson ◽  
P.F. Borrie ◽  
A.G. Stansfeld
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Polyarteritis Nodosa ◽  
Cutaneous Polyarteritis Nodosa

scholarly journals Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report

2021 ◽  
Vol 33 (4) ◽  
pp. 365
Author(s):  
Eun Hye Hong ◽  
Joon Woo Jung ◽  
Eun Joo Park ◽  
Kwang Joong Kim ◽  
Kwang Ho Kim
Keyword(s):  
Crohn’S Disease ◽  
Case Report ◽  
Crohn's Disease ◽  
Polyarteritis Nodosa ◽  
Cutaneous Polyarteritis Nodosa

Cutaneous polyarteritis nodosa and Crohn's disease

1991 ◽  
Vol 10 (2) ◽  
pp. 196-200 ◽  
Author(s):  
J. Graña Gil ◽  
P. Alonso Aquirre ◽  
M. T. Yebra Pimentel ◽  
J. Sánchez Bursón ◽  
J. L. Vázquez Iglesias ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Polyarteritis Nodosa ◽  
Cutaneous Polyarteritis Nodosa

scholarly journals O-006 Efficacy and Safety of Standard Versus Low Dose Adalimumab Maintenance Therapy as Influenced by Disease Severity in Pediatric Crohn’s Disease

2013 ◽  
Vol 19 ◽  
pp. S3-S5
Author(s):  
Jeffrey Hyams ◽  
Wallace Crandall ◽  
Joel Rosh ◽  
Frank Ruemmele ◽  
Johana Escher ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Maintenance Therapy ◽  
Disease Severity ◽  
Low Dose ◽  
Efficacy And Safety

T1241 Promotion of CD4+CD25+FOXP3+ Regulatory Cells by Oral Administration of Locally Acting Delayed Release Low-Dose 6MP Formulation Alleviated Crohn's Disease: Results of Phase I/II Clinical Trial

2010 ◽  
Vol 138 (5) ◽  
pp. S-519
Author(s):  
Eran Israeli ◽  
Gadi Lalazar ◽  
Nilla Hemed ◽  
Yoseph Caraco ◽  
Eran Goldin ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Oral Administration ◽  
Phase I ◽  
Low Dose ◽  
Regulatory Cells ◽  
Delayed Release

CMV pneumonitis in a patient with Crohn’s disease taking azathioprine

2021 ◽  
Vol 14 (4) ◽  
pp. e241256
Author(s):  
Timothy Zef Hawthorne ◽  
Rachel Shellien ◽  
Lucy Chambers ◽  
Graham Devereux
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Low Dose ◽  
Antiviral Treatment ◽  
Cmv Infection ◽  
Rare Presentation ◽  
Intravenous Ganciclovir ◽  
Increased Risk ◽  
Oral Valganciclovir

This case report discusses the rare presentation of cytomegalovirus (CMV) pneumonitis in a young patient with moderately severe Crohn’s disease managed with low dose azathioprine. CMV pneumonitis was initially suspected on CT chest images and confirmed by PCR for CMV. She was treated with intravenous ganciclovir and later stepped down to oral valganciclovir. Although this patient had a prolonged and complicated hospital admission, a good clinical outcome was achieved. CMV infection was raised as an early differential and antiviral treatment was started without delay. This case study, therefore, makes the case for increased awareness of the possibility of, and recognition of CMV pneumonitis among healthcare professionals as a way of preventing significant morbidity and mortality. It also raises awareness of checking for slow metabolisers of azathioprine before initiation to look for individuals who may be at increased risk of azathioprine’s adverse effects.

scholarly journals Low-Dose Computed Tomography for the Optimization of Radiation Dose Exposure in Patients with Crohn’s Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Richard G. Kavanagh ◽  
John O’Grady ◽  
Brian W. Carey ◽  
Patrick D. McLaughlin ◽  
Siobhan B. O’Neill ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Crohn’S Disease ◽  
Image Quality ◽  
Crohn's Disease ◽  
Radiation Dose ◽  
Ionizing Radiation ◽  
Low Dose ◽  
Radiation Doses ◽  
Radiation Dose Exposure ◽  
Ct Technology

Magnetic resonance imaging (MRI) is the mainstay method for the radiological imaging of the small bowel in patients with inflammatory bowel disease without the use of ionizing radiation. There are circumstances where imaging using ionizing radiation is required, particularly in the acute setting. This usually takes the form of computed tomography (CT). There has been a significant increase in the utilization of computed tomography (CT) for patients with Crohn’s disease as patients are frequently diagnosed at a relatively young age and require repeated imaging. Between seven and eleven percent of patients with IBD are exposed to high cumulative effective radiation doses (CEDs) (>35–75 mSv), mostly patients with Crohn’s disease (Newnham E 2007, Levi Z 2009, Hou JK 2014, Estay C 2015). This is primarily due to the more widespread and repeated use of CT, which accounts for 77% of radiation dose exposure amongst patients with Crohn’s disease (Desmond et al., 2008). Reports of the projected cancer risks from the increasing CT use (Berrington et al., 2007) have led to increased patient awareness regarding the potential health risks from ionizing radiation (Coakley et al., 2011). Our responsibilities as physicians caring for these patients include education regarding radiation risk and, when an investigation that utilizes ionizing radiation is required, to keep radiation doses as low as reasonably achievable: the “ALARA” principle. Recent advances in CT technology have facilitated substantial radiation dose reductions in many clinical settings, and several studies have demonstrated significantly decreased radiation doses in Crohn’s disease patients while maintaining diagnostic image quality. However, there is a balance to be struck between reducing radiation exposure and maintaining satisfactory image quality; if radiation dose is reduced excessively, the resulting CT images can be of poor quality and may be nondiagnostic. In this paper, we summarize the available evidence related to imaging of Crohn’s disease, radiation exposure, and risk, and we report recent advances in low-dose CT technology that have particular relevance.

Low-dose cyclosporin for Crohn's disease: implications for clinical trials

2007 ◽  
Vol 3 (2) ◽  
pp. 135-142 ◽  
Author(s):  
J. BRYNSKOV ◽  
V. BINDER ◽  
P. RIIS ◽  
K. LAURITSEN ◽  
O. SCHAFFALITZKY MUCKADELL ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Low Dose
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