Malignant transformation of phaeohyphomycosis into squamous cell carcinoma: A case report

2019 ◽  
Vol 81 (4) ◽  
pp. AB236
2019 ◽  
Vol 19 (4) ◽  
pp. 388-390
Author(s):  
Bharathi Ravikumar ◽  
S. Kumudhini ◽  
S. Krishnan

In this article, we report a case of hypertrophic lichen planus transforming into cutaneous squamous cell carcinoma in a 24-year-old Indian woman at 34 weeks of gestational age. We hypothesize that immunologic alterations during pregnancy could transform a long-standing hypertrophic lichen planus into cutaneous neoplasm.


Author(s):  
Namkha Dorji ◽  
Sangay Tshering ◽  
Sonam Choden

Introduction: Malignant transformation in mature cystic teratoma of ovary is a rare complication. Case report: A 62-year-old woman was diagnosed with squamous cell carcinoma in a mature cystic teratoma of ovary. Conclusion: Malignant transformation should be suspected in elderly woman with large mature cystic teratoma of ovary with thickened wall.


2015 ◽  
Vol 16 (2) ◽  
pp. 118-121 ◽  
Author(s):  
SM Khodeza Nahar Begum ◽  
M Alamgir Chowdhury ◽  
Afroza Suraya Mojumder ◽  
Omid Khan

Pleomorphic adenoma, though essentially benign can undergo malignant transformation. This is the case report of a 72 year old male with a giant tumor of parotid gland measuring 20.0X18.0X16.5cm & weighing 7 kg. Pleomorphic adenoma can rarely transform into carcinoma ex pleomorphic adenoma over time as it enlarges; moreover, histologically, squamous cell carcinoma (SCC) is exceedingly rare. Patient developed the tumor for a period over 20 years & it caused withdrawal from social contact. The tumor gradually enlarged without any pain or other complication except for rapid growth & pain a year before. Postoperative facial function and local control of tumor was achieved. Despite Of having a cancer with significant extracapsular invasion, our patient did not present any metastatic focus. Besides morphological patterns, authors need to categorize invasive carcinoma ex pleomorphic adenoma according to its potentiality to metastasize. Various parameters which can predict malignant transformation in pleomorphic adenoma is also yet to be explored.J MEDICINE July 2015; 16 (2) : 118-121


2021 ◽  
Vol 10 (33) ◽  
pp. 2858-2862
Author(s):  
Falguni Patel

Primary intraosseous carcinoma (PIOC) previously named as primary intraosseous squamous cell carcinoma (PIOSCC), derived from an odontogenic keratocyst (OKC) is a locally aggressive rare malignant neoplasm of the jaws with poor prognosis. The incidence of carcinomas arising from odontogenic cysts was reported to be approximately 1 – 2 / 1000. The knowledge of the histopathological features of PIOC allows accurate and early diagnosis of the lesion so that an early and appropriate treatment can be instituted for better prognosis. Primary intraosseous squamous cell carcinoma (PIOSCC) is a carcinoma arising from the central bone without any initial connection to various epithelia.1 In 2017, according to WHO classification of tumours, it was renamed as primary intraosseous carcinoma (PIOC).2 According to the current WHO classification, PIOC is a central jaw carcinoma that cannot be classified as any other condition and presumably has developed from odontogenic cysts or other benign precursors. The most common odontogenic cysts having a significant probability of malignant transformation are dentigerous cysts, residual periapical cysts, and odontogenic keratocysts (OKCs).3,4 The transition from this benign cystic lining to squamous cell carcinoma may remain clinically undetected, and the delay in diagnosis has a significant influence on treatment and prognosis.5 Therefore, the initial radiographic features of PIOC arising from an OKC (PIOC ex - OKC) are similar to those of benign odontogenic tumours or cysts, including conventional OKCs.4 Hence, it is mandatory to further investigate it histopathologically for final diagnosis and proper treatment plan. Malignant changes in OKCs have been rarely reported. To the best of our knowledge, very few cases of PIOC ex - OKC have been described in the literature. The purpose of this article is to report a case of PIOC that originated from an OKC and to shed light on the process of malignant transformation of this rare lesion. Here, is the case report describing an extremely rare case of PIOC of the maxilla derived from an OKC in a 45 - year - old female patient.


2003 ◽  
Vol 40 (138) ◽  
pp. 90-92
Author(s):  
Mamata Lakhey ◽  
K Verma ◽  
I R Khan ◽  
S P Sah ◽  
S Rani

Malignant transformation of benign cystic teratoma of ovary is rare and the mostcommon malignancy encountered is squamous cell carcinoma. The diagnosis is rarelymade preoperatively and the prognosis is usually poor. Here we report a case ofsquamous cell carcinoma arising in a dermoid in a 44 years old lady who presentedwith bilateral dermoid cysts. The preoperative findings, surgical approach andadjuvant therapy are discussed.Key Words: Malignant transformation, benign cystic teratoma, squamous cell carcinoma.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Vivian Narana Ribeiro El-Achkar ◽  
Andressa Duarte ◽  
Fabiano Pinto Saggioro ◽  
Francisco Veríssimo De Mello Filho ◽  
Jorge Esquiche León ◽  
...  

Background. The malignant transformation of laryngeal papillomatosis (LP) into squamous cell carcinoma (SCC) can occur in up to 4% of LP cases. The low-risk HPV types 6 and 11 are those that are most commonly related to LP; however, high-risk HPV types may be present. The present study reviews the literature on cases of malignant transformation of LP in adults and reports a clinical case. Case Report. A 47-year-old male patient exhibiting hoarseness for 4 months presented an exophytic lesion in the right palatine tonsil and a digitiform-like lesion in the right vocal fold. The biopsy revealed a well-differentiated SCC in the vocal cord, which showed a transition zone with a squamous papillomatous lesion. By using the chromogenic in situ hybridization (CISH) test, both lesions showed a positive result for high-risk HPV types 16 and 18 and negative for low-risk HPV types 6 and 11. The final diagnosis was SCC arising from LP. The patient underwent surgical treatment. After 36 months of follow-up, no signs of recurrence were observed. Results. The literature review revealed 25 cases of malignant transformation into SCC of LP with adult onset. Of these, only 9 cases were assessed by CISH and/or PCR for HPV identification, of which 7 were positive. The current study focuses on the eighth case, suggesting the involvement of the high-risk HPV types in its pathogenesis. Conclusions. LP is considered a benign lesion with the potential for malignant transformation, which reinforces the need for its early diagnosis and the constant monitoring of patients with LP.


Author(s):  
Vinayak Aryal ◽  
Rubina Maharjan ◽  
Moushami Singh ◽  
Adwait Marhatta ◽  
Anu Bajracharya ◽  
...  

Malignant transformation of mature cystic teratoma (MCTO) is a rare entity. Even rarer is the transformation of MCTO into undifferentiated carcinoma. We report a case of an 80-year-old woman with undifferentiated carcinoma and squamous cell carcinoma component originating from mature cystic teratoma of the ovary.


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