scholarly journals Primary Intraosseous Carcinoma Arising from Odontogenic Keratocyst - A Case Report

2021 ◽  
Vol 10 (33) ◽  
pp. 2858-2862
Author(s):  
Falguni Patel
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Who Classification ◽  
Odontogenic Keratocyst ◽  
Odontogenic Cysts ◽  
Dentigerous Cysts ◽  
Intraosseous Carcinoma

Primary intraosseous carcinoma (PIOC) previously named as primary intraosseous squamous cell carcinoma (PIOSCC), derived from an odontogenic keratocyst (OKC) is a locally aggressive rare malignant neoplasm of the jaws with poor prognosis. The incidence of carcinomas arising from odontogenic cysts was reported to be approximately 1 – 2 / 1000. The knowledge of the histopathological features of PIOC allows accurate and early diagnosis of the lesion so that an early and appropriate treatment can be instituted for better prognosis. Primary intraosseous squamous cell carcinoma (PIOSCC) is a carcinoma arising from the central bone without any initial connection to various epithelia.1 In 2017, according to WHO classification of tumours, it was renamed as primary intraosseous carcinoma (PIOC).2 According to the current WHO classification, PIOC is a central jaw carcinoma that cannot be classified as any other condition and presumably has developed from odontogenic cysts or other benign precursors. The most common odontogenic cysts having a significant probability of malignant transformation are dentigerous cysts, residual periapical cysts, and odontogenic keratocysts (OKCs).3,4 The transition from this benign cystic lining to squamous cell carcinoma may remain clinically undetected, and the delay in diagnosis has a significant influence on treatment and prognosis.5 Therefore, the initial radiographic features of PIOC arising from an OKC (PIOC ex - OKC) are similar to those of benign odontogenic tumours or cysts, including conventional OKCs.4 Hence, it is mandatory to further investigate it histopathologically for final diagnosis and proper treatment plan. Malignant changes in OKCs have been rarely reported. To the best of our knowledge, very few cases of PIOC ex - OKC have been described in the literature. The purpose of this article is to report a case of PIOC that originated from an OKC and to shed light on the process of malignant transformation of this rare lesion. Here, is the case report describing an extremely rare case of PIOC of the maxilla derived from an OKC in a 45 - year - old female patient.

scholarly journals Initial-Stage Primary Intraosseous Squamous Cell Carcinoma Derived from Odontogenic Keratocyst with Unusual Keratoameloblastomatous Change of the Maxilla: A Case Report and Literature Discussion

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Kentaro Kikuchi ◽  
Fumio Ide ◽  
Shota Takizawa ◽  
Seiji Suzuki ◽  
Hideaki Sakashita ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Malignant Neoplasm ◽  
Odontogenic Keratocyst ◽  
Odontogenic Cysts ◽  
Literature Discussion ◽  
Initial Stage ◽  
Dentigerous Cysts

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm derived from odontogenic epithelial remnants in the central jaw bone. Most PIOSCCs originate from odontogenic cysts with a nonkeratinized epithelial lining, especially from radicular/residual and dentigerous cysts. There have been few reports of PIOSCCs derived from the odontogenic keratocyst (OKC), particularly those describing pathological features at the initial stage. The diagnosis of PIOSCC is difficult and based on exclusion of other carcinomas, including metastatic tumors from other primary sites. Here, we report an extremely rare case of initial-stage PIOSCC derived from the OKC with unusual keratoameloblastomatous change of the maxilla.

scholarly journals Squamous Cell Carcinoma Arising in a Residual Cyst: A Case Report

2008 ◽  
Vol 9 (6) ◽  
pp. 115-121 ◽  
Author(s):  
Mehtap Muğlali ◽  
Ayse Pinar Sumer
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Malignant Potential ◽  
Accurate Diagnosis ◽  
Odontogenic Cysts ◽  
Epithelial Lining ◽  
Critical Elements ◽  
Cyst Lining

Aim The purpose of this report is to present a case of squamous cell carcinoma (SCC) arising from a mandibular residual cyst. Background Although rare, SCC may arise in the epithelial lining of odontogenic cysts. The diagnosis of the development of carcinoma from the cyst lining can only be established by histopatologic examination. Report A case of SCC arising from a mandibular residual cyst in a 55-year-old man is presented along with a discussion of the critical elements needed for accurate diagnosis and treatment. Summary The development of SCC from residual cysts is rare but should always be considered in the differential diagnosis. This case report clearly demonstrates the importance of clinician awareness of the malignant potential of apparently innocuous cystic lesions. It also underscores the importance of a careful histological examination and the necessity of obtaining biopsy materials from various areas to prevent a misdiagnosis of large-sized cysts. Citation Muglali M, Sumer AP. Squamous Cell Carcinoma Arising in a Residual Cyst: A Case Report. J Contemp Dent Pract 2008 September; (9)6:115-121.

Malignant Transformation of Hypertrophic Lichen Planus in a Young Pregnant Woman: A Case Report

2019 ◽  
Vol 19 (4) ◽  
pp. 388-390
Author(s):  
Bharathi Ravikumar ◽  
S. Kumudhini ◽  
S. Krishnan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Pregnant Woman ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Gestational Age ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Indian Woman

In this article, we report a case of hypertrophic lichen planus transforming into cutaneous squamous cell carcinoma in a 24-year-old Indian woman at 34 weeks of gestational age. We hypothesize that immunologic alterations during pregnancy could transform a long-standing hypertrophic lichen planus into cutaneous neoplasm.

scholarly journals Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: A case report and review of literature

2021 ◽  
Author(s):  
Namkha Dorji ◽  
Sangay Tshering ◽  
Sonam Choden
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Rare Complication ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Review Of Literature ◽  
Thickened Wall

Introduction: Malignant transformation in mature cystic teratoma of ovary is a rare complication. Case report: A 62-year-old woman was diagnosed with squamous cell carcinoma in a mature cystic teratoma of ovary. Conclusion: Malignant transformation should be suspected in elderly woman with large mature cystic teratoma of ovary with thickened wall.

scholarly journals Squamous Cell Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland – A Case Report with Clinicopathological Review

2015 ◽  
Vol 16 (2) ◽  
pp. 118-121 ◽  
Author(s):  
SM Khodeza Nahar Begum ◽  
M Alamgir Chowdhury ◽  
Afroza Suraya Mojumder ◽  
Omid Khan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Pleomorphic Adenoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Social Contact ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Metastatic Focus

Pleomorphic adenoma, though essentially benign can undergo malignant transformation. This is the case report of a 72 year old male with a giant tumor of parotid gland measuring 20.0X18.0X16.5cm & weighing 7 kg. Pleomorphic adenoma can rarely transform into carcinoma ex pleomorphic adenoma over time as it enlarges; moreover, histologically, squamous cell carcinoma (SCC) is exceedingly rare. Patient developed the tumor for a period over 20 years & it caused withdrawal from social contact. The tumor gradually enlarged without any pain or other complication except for rapid growth & pain a year before. Postoperative facial function and local control of tumor was achieved. Despite Of having a cancer with significant extracapsular invasion, our patient did not present any metastatic focus. Besides morphological patterns, authors need to categorize invasive carcinoma ex pleomorphic adenoma according to its potentiality to metastasize. Various parameters which can predict malignant transformation in pleomorphic adenoma is also yet to be explored.J MEDICINE July 2015; 16 (2) : 118-121

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