Imaging Technologies for Pre-surgical Margin Assessment of Basal Cell Carcinoma

Author(s):  
Krishan Parashar ◽  
Angeli Eloise Torres ◽  
Wyatt Boothby-Shoemaker ◽  
Indermeet Kohli ◽  
Jesse Veenstra ◽  
...  
2021 ◽  
Author(s):  
Thomas Layton

AbstractBasal cell carcinoma (BCC) is the most common malignancy in humans. Incomplete excision following conventional surgical excision requires careful consideration given the potential for disease recurrence. We performed a retrospective study analyzing facial BCC treated by conventional surgical excision to investigate factors influencing the likelihood of tumour clearance. In total, 456 cases of facial BCC were reviewed to collect a dataset of 50 tumours with involved margins and these compared to 50 completely excised tumours from the same cohort. Statistical comparison between incomplete and complete excision cases was performed using several metrics including tumour location, histology, grade, surgeon experience and method of wound reconstruction. Interestingly, our results demonstrated that only tumour location and histological type had a statistically significant impact on the completeness of resection. Infiltrative, morphoeic and mixed tumours had a higher chance of incomplete excision, as did tumours located on the inner canthus and ala nasi. In addition, the overall incomplete excision rate was 10.96% in line with previous studies. Our results help inform surgical practice and support consideration of extending the recommended macroscopic surgical margin for higher risk tumours. More research is needed to further categorize facial BCC to optimize surgical management.


2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Veronika Shavlokhova ◽  
Michael Vollmer ◽  
Andreas Vollmer ◽  
Patrick Gholam ◽  
Babak Saravi ◽  
...  

2021 ◽  
Vol 83 (1) ◽  
pp. 1618-1628
Author(s):  
Adel Mohamed Ismail ◽  
Mai Mohamed Abdelwabab ◽  
Mahmoud yassin ◽  
Said Mohamed Negm

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Shang-Hung Lin ◽  
Yu-Wen Cheng ◽  
Yi-Chien Yang ◽  
Ji-Chen Ho ◽  
Chih-Hung Lee

Background.In Asians, most basal cell carcinomas (BCCs) are pigmented with clear borders. The consensus of 4 mm surgical margin for BCC largely depends on studies in nonpigmented BCCs in Caucasians. However, little is known about recurrences of pigmented BCCs with a narrower surgical margin. We aimed to investigate 5-year recurrence of BCCs, either pigmented or nonpigmented, in Taiwanese with 3 mm surgical margin.Materials and Methods.143 patients with BCC (M/F = 66/77, average 64 years) were confirmed pathologically from 2002 to 2013. Based on the pathological margin (>1 mm, ≤1 mm, and involved), patients were categorized into the complete excision group (n=77), histology with close proximity group (n=43), and unclear surgical margin group (n=23).Results.Among 143 cases, 105 were pigmented. With standard 3 mm excision, there were 7 recurrences, with 6 of them from nonpigmented BCC group. Logistic regression showed that pigmentation was associated with lower recurrence. Interestingly, 5-year recurrence of completely excised and histology with close proximity BCC (0/77 versus 1/43) was not different statistically.Conclusions.A 3 mm surgical margin is adequate for pigmented BCC. A “wait and see” approach rather than further wide excision is appropriate for BCC with <1 mm free margin.


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