scholarly journals Facial basal cell carcinoma: a clinicopathological analysis of incomplete excision

2021 ◽  
Author(s):  
Thomas Layton
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Margin ◽  
Surgical Excision ◽  
Careful Consideration ◽  
Complete Excision ◽  
Incomplete Excision ◽  
Surgeon Experience ◽  
Tumour Location

AbstractBasal cell carcinoma (BCC) is the most common malignancy in humans. Incomplete excision following conventional surgical excision requires careful consideration given the potential for disease recurrence. We performed a retrospective study analyzing facial BCC treated by conventional surgical excision to investigate factors influencing the likelihood of tumour clearance. In total, 456 cases of facial BCC were reviewed to collect a dataset of 50 tumours with involved margins and these compared to 50 completely excised tumours from the same cohort. Statistical comparison between incomplete and complete excision cases was performed using several metrics including tumour location, histology, grade, surgeon experience and method of wound reconstruction. Interestingly, our results demonstrated that only tumour location and histological type had a statistically significant impact on the completeness of resection. Infiltrative, morphoeic and mixed tumours had a higher chance of incomplete excision, as did tumours located on the inner canthus and ala nasi. In addition, the overall incomplete excision rate was 10.96% in line with previous studies. Our results help inform surgical practice and support consideration of extending the recommended macroscopic surgical margin for higher risk tumours. More research is needed to further categorize facial BCC to optimize surgical management.

scholarly journals Treatment of Pigmented Basal Cell Carcinoma with 3 mm Surgical Margin in Asians

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Shang-Hung Lin ◽  
Yu-Wen Cheng ◽  
Yi-Chien Yang ◽  
Ji-Chen Ho ◽  
Chih-Hung Lee
Keyword(s):  
Logistic Regression ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Margin ◽  
Complete Excision ◽  
Free Margin ◽  
Close Proximity ◽  
Basal Cell Carcinomas ◽  
Wait And See

Background.In Asians, most basal cell carcinomas (BCCs) are pigmented with clear borders. The consensus of 4 mm surgical margin for BCC largely depends on studies in nonpigmented BCCs in Caucasians. However, little is known about recurrences of pigmented BCCs with a narrower surgical margin. We aimed to investigate 5-year recurrence of BCCs, either pigmented or nonpigmented, in Taiwanese with 3 mm surgical margin.Materials and Methods.143 patients with BCC (M/F = 66/77, average 64 years) were confirmed pathologically from 2002 to 2013. Based on the pathological margin (>1 mm, ≤1 mm, and involved), patients were categorized into the complete excision group (n=77), histology with close proximity group (n=43), and unclear surgical margin group (n=23).Results.Among 143 cases, 105 were pigmented. With standard 3 mm excision, there were 7 recurrences, with 6 of them from nonpigmented BCC group. Logistic regression showed that pigmentation was associated with lower recurrence. Interestingly, 5-year recurrence of completely excised and histology with close proximity BCC (0/77 versus 1/43) was not different statistically.Conclusions.A 3 mm surgical margin is adequate for pigmented BCC. A “wait and see” approach rather than further wide excision is appropriate for BCC with <1 mm free margin.

Agreement between histological subtype on punch biopsy and surgical excision in primary basal cell carcinoma

2012 ◽  
Vol 27 (7) ◽  
pp. 894-898 ◽  
Author(s):  
M.H. Roozeboom ◽  
K. Mosterd ◽  
V.J.L. Winnepenninckx ◽  
P.J. Nelemans ◽  
N.W.J. Kelleners-Smeets
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Excision ◽  
Punch Biopsy ◽  
Histological Subtype

scholarly journals Incomplete excision of basal cell carcinoma (BCC) in the head and neck region: to wait, or not to wait?

2017 ◽  
Vol 34 (6) ◽  
pp. 607-611 ◽  
Author(s):  
Jakub Miszczyk ◽  
Michał Charytonowicz ◽  
Tomasz Dębski ◽  
Bartłomiej Noszczyk
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Incomplete Excision

Staged excision of primary periocular basal cell carcinoma: absence of residual tumour in re-excised specimens: a 10-year series

2018 ◽  
Vol 103 (7) ◽  
pp. 976-979 ◽  
Author(s):  
Lindsay A McGrath ◽  
Adam Meeney ◽  
Zanna I Currie ◽  
Hardeep Singh Mudhar ◽  
Jennifer H Tan
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Significant Proportion ◽  
Surgical Excision ◽  
Lower Eyelid ◽  
Growth Patterns ◽  
Residual Tumour ◽  
Tumour Characteristics

AimsThe aim is to study staged periocular basal cell carcinoma (BCC) excision in a tertiary oculoplastic referral centre in Sheffield, UK. In particular, we examined patients with close or positive margins and no tumour seen on re-excision to identify demographics and tumour characteristics in this population.MethodsA retrospective review of medical records of 437 cases of staged periocular BCC excisions over a 10-year period (2007–2017) was carried out. Patients had surgical excision with 3 mm clinically clear margins. Staged excision was performed for all cases included in this study. Standard reconstruction techniques were employed. Histopathology was analysed for tumour type, subtype and stage.ResultsOver the 10-year period, of the 437 periocular BCCs, 156 had close or involved margins. Residual tumour was found in 29 (18.6%), whereas in 122 eyelids of 120 patients (78.2%) no residual tumour was identified on histological examination. Micronodular (54.1%) and nodular (23.7%) growth patterns of BCC, as well as lower eyelid location (72.1%), were the most prevalent in this population. Two patients (1.6%) had recurrence of BCC over a mean follow-up of 57 months (range 1–125 months).ConclusionsA significant proportion of BCCs transected on initial excision show no residual tumour in the re-excision specimens. In the interval between initial excision and re-excision, there may be eradication of the residual tumour. The exact mechanisms for this are unclear, however, and re-excision remains the appropriate recommended course in the presence of involved surgical margins of periocular BCC, particularly when high-risk tumour subtypes are encountered.

scholarly journals Differences in Rate of Complete Excision of Basal Cell Carcinoma by Dermatologists, Plastic Surgeons and General Practitioners: A Large Cross-Sectional Study

Dermatology ◽  
2018 ◽  
Vol 234 (3-4) ◽  
pp. 86-91 ◽  
Author(s):  
Kirtie Ramdas ◽  
Charlotte van Lee ◽  
Samuel Beck ◽  
Patrick Bindels ◽  
Vincent Noordhoek Hegt ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
General Practitioners ◽  
Basal Cell ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Complete Excision ◽  
Cross Sectional
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