The incidence of neovascular membranes and visual field defects from optic nerve head drusen in a large cohort of pediatric patients

2014 ◽  
Vol 18 (4) ◽  
pp. e14-e15 ◽  
Author(s):  
Jared E. Duncan ◽  
Sharon F. Freedman ◽  
Maysantoine A. El-Dairi
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Nerve Head ◽  
Pediatric Patients ◽  
Large Cohort ◽  
Visual Field Defects ◽  
Optic Nerve Head Drusen ◽  
Field Defects

scholarly journals Local Relationship between Global-Flash Multifocal Electroretinogram Optic Nerve Head Components and Visual Field Defects in Patients with Glaucoma

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Chan Hee Moon ◽  
Jungwoo Han ◽  
Young-Hoon Ohn ◽  
Tae Kwann Park
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Nerve Head ◽  
Visual Field Defect ◽  
Multifocal Electroretinogram ◽  
Visual Field Defects ◽  
Global Flash ◽  
Field Defect ◽  
Normal Controls ◽  
Field Defects

Purpose. To investigate the local relationship between quantified global-flash multifocal electroretinogram (mfERG) optic nerve head component (ONHC) and visual field defects in patients with glaucoma.Methods. Thirty-nine patients with glaucoma and 30 normal controls were enrolled. The ONHC amplitude was measured from the baseline to the peak of the second positive deflection of the induced component. The ONHC amplitude was normalized by dividing ONHC amplitude by the average of seven largest ONHC amplitudes. The ONHC amplitude ratio map and ONHC deficiency map were constructed. The local relationship between the ONHC measurements and visual field defects was evaluated by calculating the overlap between the ONHC deficiency maps and visual field defect plots.Results.The mean ONHC amplitude measurements of patients with glaucoma (6.01±1.91 nV/deg2) were significantly lower than those of the normal controls (10.29±0.94 nV/deg2) (P<0.001). The average overlap between the ONHC deficiency map and visual field defect plot was 71.4%. The highest overlap (75.0%) was between the ONHC ratios less than 0.5 and the total deviations less than 5%.Conclusions.The ONHC amplitude was reduced in patients with glaucoma compared to that in normal controls. Loss of the ONHC amplitude from the global-flash mfERG showed a high local agreement with visual field defects in patients with glaucoma.

The Relationship Between Interocular Asymmetry of Visual Field Defects and Optic Nerve Head Blood Flow in Patients With Glaucoma

2019 ◽  
Vol 28 (3) ◽  
pp. 231-237
Author(s):  
Yutaro Yamada ◽  
Tomomi Higashide ◽  
Sachiko Udagawa ◽  
Satoshi Takeshima ◽  
Kimikazu Sakaguchi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Visual Field ◽  
Optic Nerve Head ◽  
Visual Field Defects ◽  
The Relationship ◽  
Field Defects

Morphology of the optic nerve head in glaucomatous eyes with visual field defects in superior or inferior hemifield

2017 ◽  
Vol 28 (2) ◽  
pp. 175-181 ◽  
Author(s):  
Antonio Longo ◽  
Teresio Avitabile ◽  
Maurizio G. Uva ◽  
Vincenza Bonfiglio ◽  
Andrea Russo ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Nerve Head ◽  
Field Testing ◽  
Visual Field Defects ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Pattern Deviation ◽  
Control Study ◽  
Field Defects

Purpose: To evaluate the morphology of optic nerve head (ONH) and border tissue (BT) of Elschnig in glaucomatous eyes with visual field defects in superior or inferior hemifield. Methods: In a case-control study, we included 25 patients with superior arcuate scotoma, 25 patients with inferior arcuate scotoma, and 25 healthy controls. They received visual field testing, measurement of peripapillary retinal nerve fiber layer (RNFL) thickness, and ONH examination in a radial pattern with spectral-domain optical coherence tomography. In each ONH scan, the length of Bruch membrane opening (BMO) and BT were measured. Pattern deviation of 6 areas of the visual field and RNFL thickness in corresponding sectors was calculated. Results: Mean BMO length did not differ between groups. Compared with controls, glaucomatous eyes with superior scotoma had a greater BT length in inferior sectors (p<0.001), and eyes with inferior scotoma had a greater BT length in superotemporal sectors (p = 0.006). In both groups, a significant correlation was found between BT length and pattern deviation and RNFL thickness of corresponding sectors of superior and inferior hemifields. Conclusions: In patients with arcuate scotoma in one hemifield, the length of the BT correlates with glaucomatous anatomical and functional damage.

scholarly journals Optic Nerve Head Microcirculation in Eyes with Vogt-Koyanagi-Harada Disease Accompanied by Anterior Ischemic Optic Neuropathy

2021 ◽  
pp. 899-908
Author(s):  
Yui Yamashita ◽  
Yuki Hashimoto ◽  
Kenichi Namba ◽  
Kazuomi Mizuuchi ◽  
Susumu Ishida
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Disc ◽  
Optic Neuropathy ◽  
Optic Nerve Head ◽  
Visual Field Defects ◽  
Ischemic Optic Neuropathy ◽  
Optic Disc Swelling ◽  
Vkh Disease ◽  
Field Defects

Anterior ischemic optic neuropathy (AION) is infrequently complicated with Vogt-Koyanagi-Harada (VKH) disease. We quantitatively examined sequential changes in the morphology and circulation hemodynamics, using a C-scan of optical coherence tomography (OCT) and laser speckle flowgraphy (LSFG) in a patient with VKH disease accompanied by AION. A 65-year-old female complained of blurred vision in both of her eyes. The patient presented with optic disc swelling and remarkable choroidal thickening detected by OCT bilaterally. The diagnosis of VKH disease was established based on the presence of pleocytosis detected in the cerebrospinal fluid and hypofluorescent dark dots scattered all around the fundus, detected by indocyanine green angiography. Goldmann perimetry detected visual field defects, similar to superior altitudinal hemianopsia in the right eye and similar to inferior altitudinal hemianopsia in the left eye. The patient was suspected to have developed AION in both eyes. The patient received methylprednisolone pulse therapy, followed by oral prednisolone. With these treatments, the optic disc swelling disappeared. However, optic disc atrophy with visual field defects remained in both eyes. An OCT C-scan showed the ganglion cell complex (GCC) and circumpapillary retinal nerve fiber layer (cpRNFL) thickness getting thinner below the normal range, and LSFG showed the decrease in optic nerve head (ONH) tissue microcirculation. These results supported the occurrence of AION in this patient with VKH disease. The analysis of GCC and cpRNFL thickness and ONH microcirculation would be useful for supporting the occurrence of AION in a case of VKH disease.

scholarly journals To Evaluate Optic Nerve Head Changes In Patients With Primary Open Angle Glaucoma

2020 ◽  
Vol 11 (3) ◽  
pp. 4463-4467
Author(s):  
Viraj Pradhan ◽  
Karambelkar V H
Keyword(s):  
Optic Nerve ◽  
Visual Field ◽  
Optic Nerve Head ◽  
Open Angle Glaucoma ◽  
Visual Field Defects ◽  
Initial Finding ◽  
Cross Sectional ◽  
The Mean ◽  
Open Point ◽  
Field Defects

The early discovery of optic nerve head changes via careful assessment prompts initial finding and the board of essential open point glaucoma. The current examination was attempted to break down to the optic nerve head in patients of open point glaucoma regarding visual field defects.110 eyes of 60 patients were concentrated in this cross-sectional investigation. The mean age of the patients was 58.26±10.44 years, with 30 males and 30 females. 15% of the patients were suffering from hypertension. The mean IOP among the eyes was 18.63 ±4.17 mm of Hg. The mean vertical C/D ratio was 0.61 ±0.12. 89.09% of patients had a medium disc size. The R/D ratio among patients showed that majority of eyes having RD ratio of 0.01-0.1 (30.91%). HPA grades showed that 32.72% had severe visual field defects. 97.30% of eyes had a contiguous visual loss as compared to noncontiguous (2.70%). The nasal field was mostly affected by 51.35%. DDLS has a stronger correlation with Mean Defect than Vertical C/D ratio and with HPA classification than the Vertical C/D ratio. DDLS to be a simple, brisk, modest and precise strategy to record ONH harm. It seems, by all accounts, to be better than the C/D proportion for optic plate assessment.

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