Comprehensive Assessment of Peripheral Artery Disease Using Magnetic Resonance Imaging, Angiography, and Spectroscopy⁎⁎Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

The global burden of peripheral artery disease (PAD) is significant. This has led to numerous recent advances in magnetic resonance imaging (MRI) techniques in PAD. Older techniques such as time of flight MRI or phase contrast MRI are burdened by long acquisition times and significant issues with artifacts. In addition, the most used MRI modality, contrast-enhanced MR angiography (CE-MRA) is limited by the use of gadolinium contrast and its potential toxicity. Novel MRI techniques such as arterial spin labeling (ASL), blood-oxygen-level dependent imaging (BOLD), and first-pass perfusion gadolinium enhancement are advancing the field by providing skeletal muscle perfusion/oxygenation data while maintaining excellent spatial and temporal resolution. Perfusion data can be critical to providing objective clinical data of a visualized stenosis. In addition, there are a number of new MRI sequences assessing plaque composition and lesion severity in the absence of contrast. These approaches used in combination can provide useful clinical and prognostic data and provide critical endpoints in PAD research.

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Comprehensive assessment of coronary artery disease with magnetic resonance imaging

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(02)81561-3 ◽

2002 ◽

Vol 39 ◽

pp. 347

Author(s):

Sven Plain ◽

John P. Ridgway ◽

Tim R. Jones ◽

Timothy N. Bloomer ◽

Mohan U. Sivananthan

Keyword(s):

Magnetic Resonance Imaging ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Magnetic Resonance ◽

Comprehensive Assessment ◽

Resonance Imaging ◽

Artery Disease

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Deformation Measurements by Echocardiography versus Late Enhancement Magnetic Resonance Imaging in Patients with Coronary Artery Disease

European Cardiology Review ◽

10.15420/ecr.2012.8.2.101 ◽

2012 ◽

Vol 8 (2) ◽

pp. 101

Author(s):

Brage H Amundsen ◽

Anders Thorstensen ◽

Asbjørn Støylen ◽

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Keyword(s):

Magnetic Resonance Imaging ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Magnetic Resonance ◽

Late Enhancement ◽

High Temporal Resolution ◽

Resonance Imaging ◽

Deformation Imaging ◽

Artery Disease ◽

Deformation Measurements

The aim of this article is to discuss the present and future potential of deformation imaging by echocardiography and scar visualisation by magnetic resonance imaging (MRI) in patients with coronary artery disease (CAD). The two methods are clearly different: one is concerned with function, the other with morphology. Echocardiography, with its versatility of methods and high applicability, will continue to be the workhorse in cardiac imaging of patients with CAD. Important additional information can be extracted from deformation imaging methods, especially due to the high temporal resolution in tissue Doppler. Deformation measurements in 3D images are still limited by their lower resolution compared with 2D but will continue to improve. The standardisation of image analysis and the collaboration within the echocardiographic community to conduct larger studies will be important tasks in the attempt to establish evidence for the new methods. Late enhancement MRI is a method with unique properties and will continue to be an important alternative in selected patients and settings, as well as an invaluable research tool.

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