GW25-e1092 Relationship between pulse wave velocity and left ventricular diastolic function of hospitalized patients in department of cardiology

Background A sodium‐restricted diet represents a potential non‐pharmacological strategy for improving blood pressure, arterial stiffness, and left ventricular (LV) diastolic function. We investigated age‐related differences in LV structure and function and the relationship between LV function and central hemodynamics in an indigenous Papuan population, who maintain a traditional lifestyle, including a low‐salt and high‐potassium diet. Methods and Results We measured LV dimensions, transmitral blood flow, and mitral annular tissue velocities through echocardiography and Doppler imaging. Blood pressure and brachial‐ankle pulse wave velocity were measured using an automatic device (Omron). Central blood pressure and wave reflection parameters were estimated via oscillometry (Mobil‐O‐Graph, using European calibrations). A total of 82 native Papuans (median age, 42 years; 38 women; no blood pressure treatment) were enrolled. Age‐related difference in brachial systolic pressure was modest but significant, and brachial‐ankle pulse wave velocity significantly increased with age; however, LV mass index remained unchanged. LV ejection fraction and global longitudinal strain were preserved; mitral A‐wave velocity and average E/e´ increased; and e´ and E/A decreased with age. Brachial‐ankle pulse wave velocity and spot urine Na/K were positively and independently correlated with E/e´. Age and heart rate were inversely associated with E/A. In conclusion, LV systolic function was preserved; however, LV diastolic function decreased with age in Papuans. Moreover, age‐related arterial stiffening, but not wave reflections, was inversely related to LV diastolic function. Conclusions Our results suggest that arterial and LV stiffness may not be altered by sodium restriction. Longitudinal studies are warranted to elucidate the effects of diet on arterial and LV function.

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The relationship between brachial-ankle pulse wave velocity and diastolic function in essential hypertensive patients with left ventricular hypertrophy

Heart ◽

10.1136/heartjnl-2011-300867.586 ◽

2011 ◽

Vol 97 (Suppl 3) ◽

pp. A200-A200

Author(s):

C. Gailing ◽

W. Yong ◽

J. Hong ◽

W. Yun

Keyword(s):

Left Ventricular Hypertrophy ◽

Pulse Wave Velocity ◽

Diastolic Function ◽

Wave Velocity ◽

Ventricular Hypertrophy ◽

Pulse Wave ◽

Left Ventricular ◽

Hypertensive Patients ◽

The Relationship

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Reference values of left ventricular diastolic function accessed by conventional and Doppler echocardiography in healthy Angolans: effect of age and gender

10.22541/au.161169022.23653445/v1 ◽

2021 ◽

Author(s):

Humberto Morais ◽

Ana Feijão ◽

Savarino Victória Pereira

Keyword(s):

Diastolic Function ◽

Wave Velocity ◽

Reference Values ◽

Doppler Echocardiography ◽

Left Ventricular Diastolic Function ◽

Tissue Doppler ◽

Left Ventricular ◽

Tissue Doppler Echocardiography ◽

Ventricular Diastolic Function ◽

And Gender

Introduction: Studies about the reference values of the conventional and tissue Doppler echocardiography in African populations are limited. Objectives: The aim of this study is to evaluate the effect of aging and gender in left ventricular diastolic function assessed by conventional and tissue Doppler echocardiography in healthy Angolans. Methods: Cross-sectional study performed involving healthy participants aged between 18 and 85 years, attending in a diagnostic center in Luanda, Angola. Two-dimensional transthoracic echocardiography and Doppler study were performed according to the Guidelines of the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Results: A total of 103 men (47.5%) (mean age: 39,5±10,8) and 114 women (52,5%) (mean age: 43,0±12,5 years) were included. Compared to men, women were older (p=0,025) and showed significantly smaller body surface area (p<0,001). Mitral E velocity, and E/e’ ratio were significantly higher in women compared to men. While, DT of mitral E velocity was longer in men compared to women (p=0,041), E wave velocity and E/A ratio show a negative significant correlation with increasing age (r -0,33; P ≤ 0.001 and r -0,48; P ≤ 0.001, respectively). Conversely, A wave velocity shows a significant positive correlation with age (r 0,47; P < 0.001). Average e′ wave velocity shows a significant negative correlation with aging (r -0,40; P ≤ 0.0001). Conclusions: In healthy Angolan adult population, the parameters of left ventricular diastolic function deteriorated with age reflecting a normal aging process. This must be taken into account when assessing diastolic function at different age’s categories.

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