Deep brain stimulation of the subcallosal cingulate gyrus in patients with treatment-resistant depression: A double-blinded randomized controlled study and long-term follow-up in eight patients

2018 ◽  
Vol 227 ◽  
pp. 521-529 ◽  
Author(s):  
Angela Merkl ◽  
Sabine Aust ◽  
Gerd-Helge Schneider ◽  
Veerle Visser-Vandewalle ◽  
Andreas Horn ◽  
...  
2014 ◽  
Vol 5 (9) ◽  
pp. 416 ◽  
Author(s):  
Domenico Servello ◽  
Edvin Zekaj ◽  
Christian Saleh ◽  
Claudia Menghetti ◽  
Mauro Porta

2006 ◽  
Vol 34 (8) ◽  
pp. 2145-2152 ◽  
Author(s):  
William Silvester ◽  
Donna Goldsmith ◽  
Shige Uchino ◽  
Rinaldo Bellomo ◽  
Simon Knight ◽  
...  

2002 ◽  
Vol 23 (0) ◽  
pp. s111-s112 ◽  
Author(s):  
A. Tavella ◽  
B. Bergamasco ◽  
E. Bosticco ◽  
M. Lanotte ◽  
P. Perozzo ◽  
...  

2021 ◽  
Vol 201 ◽  
pp. 106449
Author(s):  
Mona Ramezani Ghamsari ◽  
Shadi Ghourchian ◽  
Maziar Emamikhah ◽  
Mahdi Safdarian ◽  
Gholamali Shahidi ◽  
...  

CNS Spectrums ◽  
2006 ◽  
Vol 11 (2) ◽  
pp. 143-148 ◽  
Author(s):  
James M. Martinez ◽  
Holly A. Zboyan

AbstractThis is the first case report of a patient who received long-term (69-month) adjunctive vagus nerve stimulation (VNS) therapy for treatment-resistant depression (TRD) and reached VNS battery end-of-service (EOS).The patient is a 41-year-old female with depression who entered a study of adjunctive VNS therapy for TRD. Her Hamilton Rating Scale for Depression (HAM-D) scores dropped from a mean of 33.5 (pre-implantation baseline period) to 16 at the end of the 12-week acute-phase treatment period, and then fluctuated from <7 (normal range) to scores in the moderately depressed range (∼20) during long-term follow-up. Three and one-half years after VNS implantation, the patient's HAM-D scores began to increase from a score of 18 to a peak score of 27 ∼ 16 months later (5-years post-implantation). The patient subsequently reported that she could no longer feel stimulation from the device and device interrogation 2 weeks later indicated battery EOS. The patient was hospitalized due to worsened depression, the pulse generator was replaced, and medication adjusted. HAM-D scores through the subsequent 9 months of followup returned to a pattern of fluctuations within the range noted during the long-term follow-up period prior to VNS battery EOS.


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