Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia

2020 ◽  
Vol 272 ◽  
pp. 24-27
Author(s):  
Yi Zhang ◽  
Junxiong Zhao ◽  
Weiping Wang ◽  
Weixing Fan ◽  
Wei Tang ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Gene Polymorphism ◽  
Mthfr Gene ◽  
Mthfr Gene Polymorphism

MTHFR Gene Polymorphism and Diabetic Retinopathy

2006 ◽  
Vol 2 (4) ◽  
pp. 467-476 ◽  
Author(s):  
Bentham Science Publisher Bentham Science Publisher
Keyword(s):  
Diabetic Retinopathy ◽  
Gene Polymorphism ◽  
Mthfr Gene ◽  
Mthfr Gene Polymorphism

Role of MTHFR gene polymorphism in the development of cardiovascular disease

2006 ◽  
Vol 22 (1) ◽  
pp. 81-81
Author(s):  
S Agrawal ◽  
S Komandur ◽  
RV Alluri ◽  
S Satyanarayana ◽  
VL Phaneeshwar ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Gene Polymorphism ◽  
Mthfr Gene ◽  
Mthfr Gene Polymorphism

Place of mthfr gene polymorphism C677T as a risk factor in obese male patients with psoriasis

2020 ◽  
Vol 40 ◽  
pp. 431
Author(s):  
R. Komsa-Penkova ◽  
B. Dimitrov ◽  
P. Tonchev ◽  
K. Gospodinova ◽  
D. Gospodinov
Keyword(s):  
Risk Factor ◽  
Gene Polymorphism ◽  
Mthfr Gene ◽  
Mthfr Gene Polymorphism ◽  
Male Patients ◽  
Obese Male

Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphism in Normal Tissue As Predictors of Fluorouracil Sensitivity

2005 ◽  
Vol 23 (7) ◽  
pp. 1365-1369 ◽  
Author(s):  
Anders Jakobsen ◽  
Jens Nederby Nielsen ◽  
Niels Gyldenkerne ◽  
Jan Lindeberg
Keyword(s):  
Gene Polymorphism ◽  
Retrospective Analysis ◽  
Thymidylate Synthase ◽  
Methylenetetrahydrofolate Reductase ◽  
Response Rate ◽  
Prospective Trial ◽  
Mthfr Gene ◽  
Mthfr Gene Polymorphism ◽  
The Difference ◽  
Methylenetetrahydrofolate Reductase Gene Polymorphism

Purpose To analyze thymidylate synthase (TS) and methylenetetrahydrofolate reductase (MTHFR) gene polymorphism with respect to fluorouracil (FU) sensitivity. Patients and Methods The study included a retrospective analysis of 88 patients with metastatic colorectal cancer and a prospective trial with 51 patients also with measurable metastases. All patients were treated with FU and leucovorin. The analysis of gene polymorphism was performed on normal intestinal tissue and lymphocytes. Results The response rate was significantly higher in patients with TS 3R/3R or MTHFR 677 TT gene polymorphism compared with the other groups. The difference of response rate translated to a difference in time to progression. Similar results were observed in the retrospective analysis and the prospective confirmatory trial. Conclusion The analysis of gene polymorphism allows delineation of a group of patients (30%) with a response rate to a single drug of approximately 50%. This information should be used in the design of tailored treatment.

The role of methylentetrahydrofolate reductase (MTHFR) gene polymorphism in intrauterine growth restriction development

2018 ◽  
Vol 12_2018 ◽  
pp. 23-28
Author(s):  
Tyutyunnik V.L. Tyutyunnik ◽  
Kan N.E. Kan ◽  
Mantrova D.A. Mantrova ◽  
Lomova N.A. Lomova N ◽  
Klimantsev I.V. Klimantsev ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Intrauterine Growth Restriction ◽  
Mthfr Gene ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Mthfr Gene Polymorphism ◽  
Methylentetrahydrofolate Reductase

Correlation Between C677T MTHFR Gene Polymorphism, Plasma Homocysteine Levels and the Incidence of CAD

2001 ◽  
Vol 1 (5) ◽  
pp. 353-361 ◽  
Author(s):  
Kenji Nakai ◽  
Chuichi Itoh ◽  
Keiko Nakai ◽  
Wataru Habano ◽  
David Gurwitz
Keyword(s):  
Gene Polymorphism ◽  
Mthfr Gene ◽  
Plasma Homocysteine ◽  
C677t Mthfr ◽  
Mthfr Gene Polymorphism
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