scholarly journals A Preliminary 18F-FDG-PET/MRI Study Shows Increased Vascular Inflammation in Moderate-to-Severe Atopic Dermatitis

2020 ◽  
Vol 8 (10) ◽  
pp. 3500-3506 ◽  
Author(s):  
Benjamin Ungar ◽  
Ana B. Pavel ◽  
Philip M. Robson ◽  
Audrey Kaufman ◽  
Alison Pruzan ◽  
...  
Bone ◽  
2014 ◽  
Vol 61 ◽  
pp. 33-38 ◽  
Author(s):  
Ville Huovinen ◽  
Virva Saunavaara ◽  
Riku Kiviranta ◽  
Miikka Tarkia ◽  
Henri Honka ◽  
...  

2021 ◽  
Vol 429 ◽  
pp. 119603
Author(s):  
Oreste Marsico ◽  
Ilaria Sammarra ◽  
Pasquale Viola ◽  
Davide Pisani ◽  
Michele Trimboli ◽  
...  
Keyword(s):  
Fdg Pet ◽  
18F Fdg ◽  

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Martina Sollini ◽  
Fabrizia Gelardi ◽  
Arturo Chiti

Several patients experience unexplained persistent symptoms after recovering from severe acute respiratory syndrome-related coronavirus disease 2 (SARS-CoV-2) [the so-called long coronavirus disease (COVID)], with a negative impact on their quality of life. We report the evolutionary track of fluorine-18-fluorodeoxyglucose positron emission tomography-computed tomography ([18F]FDG-PET/CT) in two patients incidentally diagnosed with SARS-CoV-2 infection. In both cases, baseline PET/CT showed bilateral pneumonia associated with [18F]FDG vascular uptake. Vascular uptake was more evident in the baseline scan of the asymptomatic patient. Vice versa, it was more marked in the follow-up examinations of the patient who developed long COVID. These findings suggested that vascular inflammation and its duration are responsible for the clinical course of the disease and the development of long COVID.


Allergy ◽  
2021 ◽  
Author(s):  
Axel P. Villani ◽  
Ana B. Pavel ◽  
Jianni Wu ◽  
Marie Fernandes ◽  
Catherine Maari ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7111
Author(s):  
Kevin Prigent ◽  
Jonathan Vigne

Biomedical imaging technologies offer identification of several anatomic and molecular features of disease pathogenesis. Molecular imaging techniques to assess cellular processes in vivo have been useful in advancing our understanding of several vascular inflammatory diseases. For the non-invasive molecular imaging of vascular inflammation, nuclear medicine constitutes one of the best imaging modalities, thanks to its high sensitivity for the detection of probes in tissues. 2-[18F]fluoro-2-deoxy-d-glucose ([18F]FDG) is currently the most widely used radiopharmaceutical for molecular imaging of vascular inflammatory diseases such as atherosclerosis and large-vessel vasculitis. The combination of [18F]FDG and positron emission tomography (PET) imaging has become a powerful tool to identify and monitor non-invasively inflammatory activities over time but suffers from several limitations including a lack of specificity and avid background in different localizations. The use of novel radiotracers may help to better understand the underlying pathophysiological processes and overcome some limitations of [18F]FDG PET for the imaging of vascular inflammation. This review examines how [18F]FDG PET has given us deeper insight into the role of inflammation in different vascular pathologies progression and discusses perspectives for alternative radiopharmaceuticals that could provide a more specific and simple identification of pathologies where vascular inflammation is implicated. Use of these novel PET tracers could lead to a better understanding of underlying disease mechanisms and help inform the identification and stratification of patients for newly emerging immune-modulatory therapies. Future research is needed to realize the true clinical translational value of PET imaging in vascular inflammatory diseases.


Author(s):  
Philip M. Robson ◽  
Audrey Kaufman ◽  
Alison Pruzan ◽  
Marc R. Dweck ◽  
Maria-Giovanna Trivieri ◽  
...  

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