P2-397: Neuroprotective efficacy of ANAVEX2-73, a novel tetrahydrofuran derivative targeting the sigma-1 chaperone protein, in a mouse model of Alzheimer's disease: Analyses of administration schedules and combination studies with donepezil

Tangui Maurice; Alexandre Vamvakides

doi:10.1016/j.jalz.2012.05.1107

P2-397: Neuroprotective efficacy of ANAVEX2-73, a novel tetrahydrofuran derivative targeting the sigma-1 chaperone protein, in a mouse model of Alzheimer's disease: Analyses of administration schedules and combination studies with donepezil

Alzheimer s & Dementia ◽

10.1016/j.jalz.2012.05.1107 ◽

2012 ◽

Vol 8 (4S_Part_11) ◽

pp. P402-P403

Author(s):

Tangui Maurice ◽

Alexandre Vamvakides

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Chaperone Protein ◽

Model Of Alzheimer’S Disease ◽

Sigma 1 ◽

Combination Studies ◽

Neuroprotective Efficacy ◽

Administration Schedules

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Neuroprotective Efficacy of Asparagus racemosus Root Extract on Hippocampal Neurons in Scopolamine Mouse Model of Alzheimer’s Disease

Asian Journal of Biological and Life Sciences ◽

10.5530/ajbls.2021.10.52 ◽

2021 ◽

Vol 10 (2) ◽

pp. 391-399

Author(s):

Prasad Jagdish ◽

Bhatnagar Maheep

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Hippocampal Neurons ◽

Root Extract ◽

Asparagus Racemosus ◽

Model Of Alzheimer’S Disease ◽

Neuroprotective Efficacy

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The effects of a neuroligin-1-derived peptide on behaviour in the 5XFAD mouse model of Alzheimer's disease

10.26226/morressier.5785edc6d462b80296c991f6 ◽

2016 ◽

Author(s):

Katrin Sonn

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Model Of Alzheimer’S Disease ◽

5Xfad Mouse

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Effects of Interleukin-6 trans-signalling in a mouse model of Alzheimer’s disease and high fat diet-induced obesity

10.26226/morressier.5b681764b56e9b005965c045 ◽

2018 ◽

Author(s):

Anna Escrig Monfort

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Interleukin 6 ◽

High Fat Diet ◽

High Fat ◽

Diet Induced Obesity ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020559.235469 ◽

2004 ◽

Author(s):

Karl-Peter Giese

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Procedural Learning ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1099453.555719 ◽

2008 ◽

Author(s):

Massimo Pandolfo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Model Of Alzheimer’S Disease ◽

Local Toxicity ◽

Rapid Appearance

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Faculty Opinions recommendation of Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1123163.580293 ◽

2008 ◽

Author(s):

Geneviève Dupont

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Plaques ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4693956.4576054 ◽

2010 ◽

Author(s):

Francine Benes ◽

Barbara Gisabella

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Histone Deacetylases ◽

Memory Deficits ◽

Contextual Memory ◽

Model Of Alzheimer’S Disease ◽

Class 1

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Faculty Opinions recommendation of Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5594956.5560054 ◽

2010 ◽

Author(s):

Riqiang Yan

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Amyloid Deposition ◽

Gamma Secretase ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717977209.793470743 ◽

2013 ◽

Author(s):

Matt Kaeberlein

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718520520.793504888 ◽

2015 ◽

Author(s):

Amy Barrios

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Tyrosine Phosphatase ◽

Model Of Alzheimer’S Disease

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