P4-335: HIERARCHY AND TRAJECTORIES IN IADL AND ADL IN DEMENTIA: A LONGITUDINAL ITEM RESPONSE THEORY (IRT) MODELING ON 15 YEARS OF FOLLOW-UP OF THE PAQUID COHORT

2014 ◽  
Vol 10 ◽  
pp. P910-P910
Author(s):  
Arlette Edjolo ◽  
Cécile Proust-Lima ◽  
Catherine Helmer ◽  
Fleur Delva ◽  
Jean-Francois Dartigues ◽  
...  
2021 ◽  
Author(s):  
Jakob Bue Bjorner ◽  
Berend Terluin ◽  
Andrew Trigg ◽  
Jinxiang Hu ◽  
Keri J.S. Brady ◽  
...  

Abstract PURPOSE: Thresholds for meaningful within-individual change (MWIC) are useful for interpreting patient-reported outcome measures (PROM). Transition ratings (TR) have been recommended as anchors to establish MWIC. Traditional statistical methods for analyzing MWIC such as mean change analysis, receiver operating characteristic (ROC) analysis, and predictive modeling ignore problems of floor/ceiling effects and measurement error in the PROM scores and the TR item. We present a novel approach to MWIC estimation for multi-item scales using longitudinal item response theory (LIRT).METHODS: A Graded Response LIRT model for baseline and follow-up PROM data was expanded to include a TR item measuring latent change. The LIRT threshold parameter for the TR established the MWIC threshold on the latent metric, from which the observed PROM score MWIC threshold was estimated. We compared the LIRT approach and traditional methods using an example data set with baseline and three follow-up assessments differing by magnitude of score improvement, variance of score improvement, and baseline-follow-up score correlation.RESULTS: The LIRT model provided good fit to the data. LIRT estimates of observed PROM MWIC varied between 3 and 4 points score improvement. In contrast, results from traditional methods varied from 2 points to 10 points - strongly associated with proportion of self-rated improvement. Best agreement between methods was seen when approximately 50% rated their health as improved.CONCLUSION : Results from traditional analyses of anchor-based MWIC are impacted by study conditions. LIRT constitutes a promising and more robust analytic approach to identifying thresholds for MWIC.


2020 ◽  
Vol 9 (11) ◽  
pp. 3754
Author(s):  
Yoshiaki Nomura ◽  
Toshiya Morozumi ◽  
Mitsuo Fukuda ◽  
Nobuhiro Hanada ◽  
Erika Kakuta ◽  
...  

Periodontal examination data have a complex structure. For epidemiological studies, mass screenings, and public health use, a simple index that represents the periodontal condition is necessary. Periodontal indices for partial examination of selected teeth have been developed. However, the selected teeth vary between indices, and a justification for the selection of examination teeth has not been presented. We applied a graded response model based on the item response theory to select optimal examination teeth and sites that represent periodontal conditions. Data were obtained from 254 patients who participated in a multicenter follow-up study. Baseline data were obtained from initial follow-up. Optimal examination sites were selected using item information calculated by graded response modeling. Twelve sites—maxillary 2nd premolar (palatal-medial), 1st premolar (palatal-distal), canine (palatal-medial), lateral incisor (palatal-central), central incisor (palatal-distal) and mandibular 1st premolar (lingual, medial)—were selected. Mean values for clinical attachment level, probing pocket depth, and bleeding on probing by full mouth examinations were used for objective variables. Measuring the clinical parameters of these sites can predict the results of full mouth examination. For calculating the periodontal index by partial oral examination, a justification for the selection of examination sites is essential. This study presents an evidence-based partial examination methodology and its modeling.


2018 ◽  
Vol 27 (7) ◽  
pp. 1721-1734 ◽  
Author(s):  
Carrie R. Houts ◽  
Robert Morlock ◽  
Steven I. Blum ◽  
Michael C. Edwards ◽  
R. J. Wirth

Methods ◽  
2022 ◽  
Author(s):  
Cécile Proust-Lima ◽  
Viviane Philipps ◽  
Bastien Perrot ◽  
Myriam Blanchin ◽  
Véronique Sébille

2017 ◽  
Vol 6 (9) ◽  
pp. 635-641 ◽  
Author(s):  
Marc Vandemeulebroecke ◽  
Björn Bornkamp ◽  
Tillmann Krahnke ◽  
Johanna Mielke ◽  
Andreas Monsch ◽  
...  

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