scholarly journals P4-663: INITIATION OF THE PHASE 2/3 GAIN TRIAL OF COR388, A NOVEL BACTERIAL VIRULENCE FACTOR INHIBITOR FOR THE TREATMENT OF ALZHEIMER'S DISEASE (AD) BASED ON PHASE I A/B SAFETY, PK, BIOMARKER AND EFFICACY DATA

2019 ◽  
Vol 15 ◽  
pp. P1585-P1585
Author(s):  
Mike Detke ◽  
Casey Lynch ◽  
Leslie Holsinger ◽  
Shirin Kapur ◽  
Dave Hennings ◽  
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Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Phase I ◽  
Virulence Factor ◽  
Bacterial Virulence ◽  
Phase 2 ◽  
Efficacy Data ◽  
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scholarly journals ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer’s disease

Nature Aging ◽  
2021 ◽  
Vol 1 (6) ◽  
pp. 521-534
Author(s):  
Petr Novak ◽  
Branislav Kovacech ◽  
Stanislav Katina ◽  
Reinhold Schmidt ◽  
Philip Scheltens ◽  
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Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Active Immunotherapy ◽  
Phase 2 ◽  
Phase 2 Study ◽  
Randomized Phase 2

Purification of bacterial virulence factor pertactin using high affinity ligands

2020 ◽  
Vol 164 ◽  
pp. 107760
Author(s):  
Umatheny Umatheva ◽  
Braden Sweeting ◽  
Léo Sauvaget ◽  
Nerissa Dela Rosa ◽  
John Riley ◽  
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Keyword(s):  
Virulence Factor ◽  
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Affinity Ligands ◽  
High Affinity ◽  
Bacterial Virulence Factor

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2010 ◽  
Vol 107 (41) ◽  
pp. 17739-17744 ◽  
Author(s):  
Janine H. Peterson ◽  
Pu Tian ◽  
Raffaele Ieva ◽  
Nathalie Dautin ◽  
Harris D. Bernstein
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Virulence Factor ◽  
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scholarly journals Longitudinal flortaucipir accumulation is spatially distinct across baseline tau burden stages: Summary from three phase 2/3 interventional trials in Alzheimer’s disease

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Sergey Shcherbinin ◽  
Ixavier A. Higgins ◽  
Ming Lu ◽  
Michael J. Pontecorvo ◽  
Albert C. Lo ◽  
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Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Phase 2 ◽  
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