Characterization of Novel Immune Checkpoint Receptors within the Breast Cancer Tumor Microenvironment

2017 ◽  
Vol 225 (4) ◽  
pp. S21
Author(s):  
Austin D. Williams ◽  
Kyle K. Payne ◽  
Alycia So ◽  
Jose Conejo-Garcia ◽  
Julia C. Tchou
Keyword(s):  
Breast Cancer ◽  
Tumor Microenvironment ◽  
Immune Checkpoint ◽  
Cancer Tumor ◽  
Checkpoint Receptors

scholarly journals Abstract 3145: Characterization of novel immune checkpoint receptors within the breast cancer tumor microenvironment

2018 ◽  
Author(s):  
Austin D. Williams ◽  
Jean S. Campbell ◽  
Lauri D. Aicher ◽  
Kyle K. Payne ◽  
Jose R. Conejo-Garcia ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Microenvironment ◽  
Immune Checkpoint ◽  
Cancer Tumor ◽  
Checkpoint Receptors

The Expression of Immune Checkpoint Receptors and Ligands in the Colorectal Cancer Tumor Microenvironment

2021 ◽  
Vol 41 (10) ◽  
pp. 4895-4905
Author(s):  
PRAJWAL NEUPANE ◽  
KOSAKU MIMURA ◽  
SHOTARO NAKAJIMA ◽  
HIROKAZU OKAYAMA ◽  
MISATO ITO ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Microenvironment ◽  
Immune Checkpoint ◽  
Cancer Tumor ◽  
Checkpoint Receptors

Abstract P5-04-23: Characterization of the tumor microenvironment in a large series of ER/PR negative breast cancer

2020 ◽  
Author(s):  
Hanne Vos ◽  
Kathleen Lambein ◽  
Giuseppe Floris ◽  
Bram Mariën ◽  
Lieze Berben ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Microenvironment ◽  
Large Series

Distribution of novel immune-checkpoint targets in ovarian cancer tumor microenvironment: A dynamic landscape.

2021 ◽  
Vol 160 (1) ◽  
pp. 279-284
Author(s):  
Félix Blanc-Durand ◽  
Catherine Genestie ◽  
Elisa Yaniz Galende ◽  
Sébastien Gouy ◽  
Philippe Morice ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Tumor Microenvironment ◽  
Immune Checkpoint ◽  
Dynamic Landscape ◽  
Cancer Tumor

scholarly journals Impact of the Tumor Microenvironment on Tumor-Infiltrating Lymphocytes: Focus on Breast Cancer

2017 ◽  
Vol 11 ◽  
pp. 117822341773156 ◽  
Author(s):  
Ivan J Cohen ◽  
Ronald Blasberg
Keyword(s):  
Breast Cancer ◽  
Immune Response ◽  
Clinical Trials ◽  
Tumor Microenvironment ◽  
Immune Checkpoint ◽  
Tumor Infiltrating Lymphocytes ◽  
Breast Tumors ◽  
Immune Checkpoint Blockade ◽  
Physical Barriers ◽  
Infiltrating Lymphocytes

Immunotherapy is revolutionizing cancer care across disciplines. The original success of immune checkpoint blockade in melanoma has already been translated to Food and Drug Administration–approved therapies in a number of other cancers, and a large number of clinical trials are underway in many other disease types, including breast cancer. Here, we review the basic requirements for a successful antitumor immune response, with a focus on the metabolic and physical barriers encountered by lymphocytes entering breast tumors. We also review recent clinical trials of immunotherapy in breast cancer and provide a number of interesting questions that will need to be answered for successful breast cancer immunotherapy.

Sign in / Sign up

Export Citation Format

Share Document