Bacterially expressed and refolded envelope protein (domain III) of dengue virus type-4 binds heparan sulfate

2007 ◽  
Vol 846 (1-2) ◽  
pp. 184-194 ◽  
Author(s):  
Priyabrata Pattnaik ◽  
J. Pradeep Babu ◽  
Shailendra Kumar Verma ◽  
Vijay Tak ◽  
P.V. Lakshmana Rao
Keyword(s):  
Dengue Virus ◽  
Heparan Sulfate ◽  
Virus Type ◽  
Envelope Protein ◽  
Protein Domain ◽  
Domain Iii

scholarly journals Thioaptamers targeting dengue virus type-2 envelope protein domain III

2014 ◽  
Vol 453 (3) ◽  
pp. 309-315 ◽  
Author(s):  
Sai Hari A. Gandham ◽  
David E. Volk ◽  
Ganesh L.R. Lokesh ◽  
Muniasamy Neerathilingam ◽  
David G. Gorenstein
Keyword(s):  
Dengue Virus ◽  
Virus Type ◽  
Envelope Protein ◽  
Protein Domain ◽  
Domain Iii ◽  
Dengue Virus Type 2

Dengue virus envelope protein domain III-elicited antibodies mediate cross-protection against Zika virus in a mouse model

2020 ◽  
Vol 278 ◽  
pp. 197882
Author(s):  
Yongchao Zhou ◽  
Dong Chen ◽  
Lan Yang ◽  
Weiwei Zou ◽  
Zhiliang Duan ◽  
...  
Keyword(s):  
Mouse Model ◽  
Dengue Virus ◽  
Zika Virus ◽  
Envelope Protein ◽  
Cross Protection ◽  
Protein Domain ◽  
Virus Envelope ◽  
Virus Envelope Protein ◽  
Domain Iii

scholarly journals Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

2009 ◽  
Vol 83 (9) ◽  
pp. 4338-4344 ◽  
Author(s):  
Vinod Nayak ◽  
Moshe Dessau ◽  
Kaury Kucera ◽  
Karen Anthony ◽  
Michel Ledizet ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dengue Virus ◽  
Conformational Change ◽  
Virus Type ◽  
Envelope Protein ◽  
Lipid Membrane ◽  
Ph Sensor ◽  
Endosomal Membrane ◽  
Domain Iii

ABSTRACT Dengue virus relies on a conformational change in its envelope protein, E, to fuse the viral lipid membrane with the endosomal membrane and thereby deliver the viral genome into the cytosol. We have determined the crystal structure of a soluble fragment E (sE) of dengue virus type 1 (DEN-1). The protein is in the postfusion conformation even though it was not exposed to a lipid membrane or detergent. At the domain I-domain III interface, 4 polar residues form a tight cluster that is absent in other flaviviral postfusion structures. Two of these residues, His-282 and His-317, are conserved in flaviviruses and are part of the “pH sensor” that triggers the fusogenic conformational change in E, at the reduced pH of the endosome. In the fusion loop, Phe-108 adopts a distinct conformation, forming additional trimer contacts and filling the bowl-shaped concavity observed at the tip of the DEN-2 sE trimer.

scholarly journals Suppressive effect of dengue virus envelope protein domain III on megakaryopoiesis

Virulence ◽  
2017 ◽  
Vol 8 (8) ◽  
pp. 1719-1731 ◽  
Author(s):  
Guan-Ling Lin ◽  
Hsin-Hou Chang ◽  
Te-Sheng Lien ◽  
Po-Kong Chen ◽  
Hao Chan ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Envelope Protein ◽  
Suppressive Effect ◽  
Protein Domain ◽  
Virus Envelope ◽  
Virus Envelope Protein ◽  
Domain Iii

scholarly journals Anti-dengue virus envelope protein domain III IgG ELISA among infants with primary dengue virus infections

Acta Tropica ◽  
2015 ◽  
Vol 142 ◽  
pp. 103-107 ◽  
Author(s):  
Daniel H. Libraty ◽  
Lei Zhang ◽  
AnaMae Obcena ◽  
Job D. Brion ◽  
Rosario Z. Capeding
Keyword(s):  
Dengue Virus ◽  
Envelope Protein ◽  
Protein Domain ◽  
Virus Infections ◽  
Virus Envelope ◽  
Virus Envelope Protein ◽  
Domain Iii

scholarly journals Domain-III FG loop of the dengue virus type 2 envelope protein is important for infection of mammalian cells and Aedes aegypti mosquitoes

Virology ◽  
2010 ◽  
Vol 406 (2) ◽  
pp. 328-335 ◽  
Author(s):  
Steven M. Erb ◽  
Siritorn Butrapet ◽  
Kelley J. Moss ◽  
Betty E. Luy ◽  
Thomas Childers ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Dengue Virus ◽  
Virus Type ◽  
Envelope Protein ◽  
Mammalian Cells ◽  
Domain Iii ◽  
Dengue Virus Type 2
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