Effects of stellate ganglion block on cardiovascular reaction and heart rate variability in elderly patients during anesthesia induction and endotracheal intubation

2015 ◽  
Vol 27 (2) ◽  
pp. 140-145 ◽  
Author(s):  
Yong-Quan Chen ◽  
Xiao-Ju Jin ◽  
Zhao-Fang Liu ◽  
Mei-Fang Zhu
2010 ◽  
Vol 58 (1) ◽  
pp. 56 ◽  
Author(s):  
Jang Jae Kim ◽  
Rack Kyung Chung ◽  
Hee Seung Lee ◽  
Jong In Han

Author(s):  
Sana Yasmin Hussain ◽  
Arijit Sardar ◽  
Dhruv Jain ◽  
Lokesh Kashyap

Intra-arterial drug administration is a rare but potentially dreadful condition which can result in ischemia and gangrene of the hand. In the present case we accidentally injected propofol in an anomalous radial artery during anesthesia induction. Serial ultrasound-guided stellate ganglion blocks were applied to salvage the limb of the patient by promoting arterial blood flow. This is probably the first reported case of accidental intra-arterial injection of propofol being managed with stellate ganglion block.


1996 ◽  
Vol 84 (4) ◽  
pp. 843-850. ◽  
Author(s):  
Takehiko Ikeda ◽  
Satoshi Iwase ◽  
Yoshiki Sugiyama ◽  
Toshiyoshi Matsukawa ◽  
Tadaaki Mano ◽  
...  

Background Left stellate ganglion block has been shown to increase heart rate and blood pressure, possible because of blockage of afferent vagal fibers from arterial baroreceptors in the aortic arch. Because efferent muscle sympathetic nerve activity (MSNA) is influenced by the arterial baroreflex, the hypothesis that left stellate ganglion block increases efferent MSNA recorded from the tibial nerve of humans was tested. Methods Twenty healthy male volunteers were sequentially assigned to one of three groups: stellate ganglion block (n = 10), in which 7 ml 1% mepivacaine was injected into the left stellate ganglion; placebo (n = 5), in which 7 ml of saline was injected into the left stellate ganglion; and intramuscular injection (n = 5), in which 7 ml mepivacaine was injected into the left deltoid muscle. Direct intraneural microneurographic recording with a tungsten microelectrode was used to record MSNA in the left tibial nerve. MSNA, heart rate, and blood pressure were recorded before and after injection in all groups. An additional five volunteers were studied with transthoracic echocardiography to examine the effect of stellate ganglion block on preload changes. Results Tibial nerve MSNA increased after mepivacaine injection to the left stellate ganglion but was unchanged after saline injection to the left stellate ganglion or mepivacaine injection into the deltoid muscle. Heart rate increased significantly after the left stellate ganglion block but did not change significantly after saline injection to the left stellate ganglion or after mepivacaine injection to the deltoid muscle. Systemic blood pressure did not change significantly in all groups. Left ventricular end-diastolic area and left ventricular end-diastolic circumference did not change after stellate ganglion block. Conclusions Tibial nerve MSNA increased during left stellate ganglion block with mepivacaine.


2015 ◽  
Vol 2;18 (2;3) ◽  
pp. 173-178
Author(s):  
Younghoon Jeon

Background: The sympathetic nervous system plays an important role in the arousal response. Recently, the stellate ganglion block (SGB) was found to effectively treat anxiety and night awakening in humans and decrease electroencephalogram (EEG) indices of arousal responses in rat. But, the role of the sympathetic block in human arousal responses has not yet been studied. Objective: We performed this prospective, double-blinded, controlled volunteer study to investigate the sedative effects and bispectral index (BIS) changes of SGB. Study Design: A randomized, double-blind trial. Setting: Single academic medical center. Methods: This study was approved by the Ethics Committee of Kyungpook National University Hospital (ref: KNUH_10-1081) and registered with CRiS (Clinical Research Information Service, http://cris.cdc.go.kr, ref: KCT0000036, 2010. 9.24). Twenty healthy volunteers were enrolled in this study. The volunteers were randomly assigned to one of 2 groups: the SGB group (n = 10) and the sham group (n =10). Volunteers in SGB group received SGB and volunteers in the sham group received a sham procedure. BIS value, heart rate, and blood pressure were measured before and 5, 10, 20, and 30 minutes after the procedure. Observer’s Assessment of Alertness/Sedation (OAA/S) scores were assessed before and 10 and 30 minutes after the intervention. Results: In the SGB group, BIS values and OAA/S scores significantly decreased after the intervention as compared to baseline (P < 0.05). The values were also significantly decreased in the SGB group when compared to the values in sham group after the intervention (P < 0.05). There was a significant change of mean blood pressure 10 to 30 minutes after SGB (P < 0.05). There were no differences in heart rate during study period between groups. Limitations: This study is limited by a relatively small sample size. Conclusions: This study showed that SGB has a sedative effect in normal healthy volunteers, as evidenced by decreased OAA/S scores and BIS values. Key words: Stellate ganglion, sympathetic block, sedation, bisepctral index, EEG, volunteers


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