Differential expression of TLR3 and TLR4 in keratocystic odontogenic tumor (KCOT): A comparative immunohistochemical study in primary, recurrent, and nevoid basal cell carcinoma syndrome (NBCCS)–associated lesions

ABSTRACT Nevoid basal cell carcinoma syndrome is a syndrome with wide variety of manifestations ranging from oral lesions to skeletal deformities. It calls for due responsibility of maxillofacial surgeon to diagnose the syndrome because very often they are the first health professionals to see the patient for the treatment of keratocystic odontogenic tumor. Keratocystic odontogenic tumor (KCOT) has been the topic of numerous investigators and is known for its potentially aggressive behavior and significant rate of recurrences. Keratocystic odontogenic tumor often occurs as a solitary lesion, and in some instances multiple keratocysts may occur in association with a syndrome called Gorlin-Goltz syndrome (nevoid basal cell carcinoma, jaw cyst bifid rib basal cell nevus syndrome). Here, we present a case of multiple keratocysts in the mandible in association with skeletal, ocular and cutaneous anomalies in the given clinical scenario which has profound relevance in the clinical dental practice. How to cite this article Kulkarni GH, Khaji SI, Kulkarni HS, Metkari SB, Kulkarni R. Multiple Keratocysts of the Mandible in Association with Multiple Basal Epithelioma, Jaw Cysts and Bifid Rib Syndrome: A Rare Case Report. Int J Head Neck Surg 2014;5(1):39-41.

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Analysis of the neoplastic nature and biological potential of sporadic and nevoid basal cell carcinoma syndrome-associated keratocystic odontogenic tumor

Journal of Oral Pathology and Medicine ◽

10.1111/j.1600-0714.2007.00578.x ◽

2007 ◽

Vol 36 (9) ◽

pp. 550-554 ◽

Cited By ~ 14

Author(s):

Naoki Katase ◽

Hitoshi Nagatsuka ◽

Hidetsugu Tsujigiwa ◽

Mehmet Gunduz ◽

Ryo Tamamura ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Odontogenic Tumor ◽

Keratocystic Odontogenic Tumor ◽

Biological Potential

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Conservative Treatment Protocol of Keratocystic Odontogenic Tumor: Report of a Case with Nevoid Basal Cell Carcinoma Syndrome and Literature Review

Journal of Maxillofacial and Oral Surgery ◽

10.1007/s12663-014-0689-6 ◽

2014 ◽

Vol 14 (S1) ◽

pp. 475-481

Author(s):

Dariush Hasheminia ◽

Vahid Naemi ◽

Navid Naghdi

Keyword(s):

Basal Cell Carcinoma ◽

Conservative Treatment ◽

Literature Review ◽

Cell Carcinoma ◽

Basal Cell ◽

Treatment Protocol ◽

Odontogenic Tumor ◽

Keratocystic Odontogenic Tumor

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Nonsyndromic Bilateral Keratocystic Odontogenic Tumor: A Rare Case

World Journal of Dentistry ◽

10.5005/jp-journals-10015-1110 ◽

2011 ◽

Vol 2 (4) ◽

pp. 342-345

Author(s):

Vinod Kumar ◽

Chaitanya Babu ◽

Geetanshu Dawar

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Male Patient ◽

Basal Cell ◽

Rare Case ◽

Odontogenic Tumor ◽

Keratocystic Odontogenic Tumor ◽

Fourth Decade ◽

Bilateral Lesions

ABSTRACT Here, we report a case of keratocystic odontogenic tumor occurring bilaterally in a male patient in fourth decade of life. This case is different from bilateral lesions of keratocystic odontogenic tumor which are most commonly parakeratinized and are associated with syndromes like nevoid basal cell carcinoma syndrome. In our case, we could not find out any syndromic association and furthermore histopathology was in line of orthokeratinization.

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